Anifrolumab

A4DAB018 | Immune-mediated / inflammatory disorders | Approved
IFNAR1
G1 / IgG1
Medarex Medical University of Vienna MedImmune
Approved
Whole mAb
MDX-1333 MDX1333 MEDI-546 MEDI546 Saphnelo
5.9
IMGT PubChem (164144448) PubChem (249565938) PubChem (347911264) PubChem (381126987) PubChem (472220765) PubChem (472423585) PubChem (472435507) PubChem (472439886) PubChem (481155515) PubChem (483928463) PubChem (498153723) PubChem (508534504) Thera-SAbDab YAbS
Avg A4D Score
-0.7188
Score Range
-0.72
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB018_4qxg_H_L 4qxg 100% -0.7188 6.5 4.0 -0.392 -0.7567