Bebtelovimab

A4DAB036 | Approved

Target SARS-CoV-2 Spike RBD

Isotype / Subclass G1 / None

Company

Eli Lilly AbCellera

Clinical Status Approved

Format Whole mAb

Synonyms

LY-3853113 LY3853113 LY-CoV1404 LY CoV1404

pH Formulation —

IMGT PubChem (442108338) PubChem (461565936) PubChem (461663476) PubChem (472424854) PubChem (483558686) PubChem (483559435) PubChem (483929079) PubChem (513906971) Thera-SAbDab YAbS

Avg A4D Score

-0.6751

Score Range

-0.68 to -0.67

Structures

Avg. A4D Score per Structure

pH at Min / Max Aggregation Propensity

Structure ID	Source PDB	Seq. Identity	Avg. A4D Score	pH (Min Agg.)	pH (Max Agg.)	Score CDR	Score non-CDR
A4DAB036_7mmo_A_B	7mmo	100%	-0.6817	6.5	4.0	-0.5449	-0.6995
A4DAB036_7mmo_D_E	7mmo	100%	-0.6686	6.5	4.0	-0.4763	-0.6939

Bebtelovimab

Avg. A4D Score per Structure

pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2