Benufutamab

A4DAB041 | Phase-I/II

Target TNFRSF10B/CD262/DR5/TRAILR2

Isotype / Subclass G1 / None

Company

Genmab VU University Medical Center iDD Biotech

Clinical Status Phase-I/II

Format Whole mAb

Synonyms

GEN1029 GEN-1029 Hx-DR5-01 Hx-DR5-05 iDD 004 iDD-004 iDD004

pH Formulation —

IMGT PubChem (402425701) PubChem (472420478) PubChem (476262800) PubChem (476269468) Thera-SAbDab YAbS

Avg A4D Score

-0.7416

Score Range

-0.76 to -0.72

Structures

Structure ID	Source PDB	Seq. Identity	Avg. A4D Score	pH (Min Agg.)	pH (Max Agg.)	Score CDR	Score non-CDR
A4DAB041_6t3j_A_B	6t3j	100%	-0.7215	6.5	9.0	-0.5133	-0.7458
A4DAB041_6t3j_F_G	6t3j	100%	-0.7617	6.5	4.0	-0.5293	-0.7887