Berlimatoxumab

A4DAB042 | Phase-II
Staphylococcus aureus Toxin A
G1 / None
Adimab Arsanis X4 Pharmaceuticals
Phase-II
Whole mAb
ASN-2 ASN2 ASN200 (combination of atidortoxumab and berlimatoxumab) ASN-200
—
IMGT PubChem (381128180) PubChem (472421052) PubChem (476262802) PubChem (476269470) Thera-SAbDab YAbS
Avg A4D Score
-0.6749
Score Range
-0.69 to -0.66
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB042_5k59_H_L 5k59 100% -0.6908 6.0 9.0 -0.4012 -0.726
A4DAB042_5k59_E_F 5k59 100% -0.659 6.0 9.0 -0.3483 -0.6971