Betinukibart

A4DAB043 | Immune-mediated / inflammatory disorders | Phase-III
IL17A
G1 / IgG1
Shanghai Huaota Biopharmaceutical Shenzhen Bay Laboratory
Phase-III
Whole mAb
Hb0017 Hb-0017
—
IMGT PubChem (507427492) PubChem (520376942) Thera-SAbDab YAbS
Avg A4D Score
-0.6401
Score Range
-0.65 to -0.63
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB043_7wkx_B_D 7wkx 100% -0.6302 6.5 4.0 -0.0921 -0.6998
A4DAB043_7wkx_A_C 7wkx 100% -0.6499 6.5 4.0 -0.0985 -0.7199