Bococizumab

A4DAB052 | Cardiovascular / hemostasis disorders | Phase-III
PCSK9
G2 / IgG2
Halozyme Therapeutics Pfizer
Phase-III
Whole mAb
PF-04950615 PF04950615 PF-4950615 PF4950615 RN-316 RN316
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IMGT PubChem (194168554) PubChem (223366063) PubChem (347911335) PubChem (381127283) PubChem (472404650) PubChem (472435520) PubChem (472440368) PubChem (481155505) PubChem (505565523) Thera-SAbDab YAbS
Avg A4D Score
-0.6573
Score Range
-0.66
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB052_3sqo_H_L 3sqo 100% -0.6573 6.5 9.0 0.0915 -0.7462