Burosumab

A4DAB056 | Skeletal disorders | Approved
FGF23
G1 / IgG1
Kyowa Hakko Kirin Ultragenyx Pharmaceutical
Approved
Whole mAb
Crysvita KRN 23 KRN23 KRN-23 UX 023 UX023 UX-023
6.25
IMGT PubChem (318164811) PubChem (318464563) PubChem (381127714) PubChem (404771481) PubChem (472264636) PubChem (472408595) PubChem (476262723) PubChem (476269041) PubChem (481155334) PubChem (483928646) PubChem (498151791) Thera-SAbDab YAbS
Avg A4D Score
-0.6481
Score Range
-0.65
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB056_7ven_B_A 7ven 100% -0.6481 6.5 9.0 -0.2456 -0.6936