Daclizumab

A4DAB079 | Approved
IL2RA/CD25
G1 / None
AbbVie Biogen Dana-Farber Cancer Institute National Cancer Institute (USA) PDL BioPharma
Approved
Whole mAb
BIIB-019 BIIB019 Dacliximab RO 247375 RO247375 RO-247375 Zenapax Zinbryta
6
IMGT PubChem (538071) PubChem (46504469) PubChem (50067188) PubChem (103771419) PubChem (135342174) PubChem (178103462) PubChem (329976980) PubChem (464011639) PubChem (468568979) PubChem (472264639) PubChem (472399229) PubChem (481101586) PubChem (481155335) PubChem (486455968) PubChem (517704477) Thera-SAbDab YAbS
Avg A4D Score
-0.725
Score Range
-0.74 to -0.71
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB079_3nfp_H_L 3nfp 100% -0.7437 6.5 4.0 -0.2778 -0.7947
A4DAB079_3nfp_A_B 3nfp 100% -0.7182 6.5 4.0 -0.274 -0.7669
A4DAB079_3nfs_H_L 3nfs 100% -0.7131 6.5 4.0 -0.295 -0.7595