Drozitumab

A4DAB091 | Phase-II

Target TNFRSF10B/CD262/DR5/TRAILR2

Isotype / Subclass G1 / None

Company

Genentech

Clinical Status Phase-II

Format Whole mAb

Synonyms

PRO-95780 PRO95780 RG7425 RG-7425

pH Formulation —

IMGT PubChem (135329142) PubChem (160693414) PubChem (472398111) PubChem (474488724) PubChem (474489060) PubChem (513904547) Thera-SAbDab YAbS

Avg A4D Score

-0.7408

Score Range

-0.74

Structures

Structure ID	Source PDB	Seq. Identity	Avg. A4D Score	pH (Min Agg.)	pH (Max Agg.)	Score CDR	Score non-CDR
A4DAB091_4od2_B_A	4od2	100%	-0.7408	6.5	9.0	-0.5736	-0.7632