Emactuzumab

A4DAB102 | Cancer | Phase-III
CSF1R/CD115/M-CSFR
G1 / IgG1
Roche University of Texas M. D. Anderson Cancer Center
Phase-III
Whole mAb
RG-7155 RG7155 RO-5509554 RO5509554
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IMGT PubChem (310264725) PubChem (312468220) PubChem (381127464) PubChem (404772350) PubChem (472408545) PubChem (472435564) PubChem (472439870) PubChem (498152583) PubChem (505586462) Thera-SAbDab YAbS
Avg A4D Score
-0.6996
Score Range
-0.7
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB102_4liq_H_L 4liq 100% -0.6996 6.5 4.0 -0.3757 -0.7351