Enlonstobart

A4DAB104 | Cancer | Approved
PDCD1/CD279/PD1
G4 / IgG4
Hangzhou Sumgen Biotech CSPC ZhongQi Pharmaceutical Technology Hangzhou Sumgen Biotech
Approved
Whole mAb
SG 001 SG-001 SG001 SYSA-1802 SYSA 1802 SYSA1802
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IMGT PubChem (478838800) PubChem (485483330) PubChem (485511897) PubChem (494431275) PubChem (507750422) Thera-SAbDab YAbS
Avg A4D Score
-0.7558
Score Range
-0.78 to -0.71
Structures
4
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB104_5ggr_H_L 5ggr 97% -0.7582 6.5 4.0 -0.7577 -0.7583
A4DAB104_5ggq_H_L 5ggq 97% -0.7717 6.5 4.0 -0.8002 -0.7687
A4DAB104_5wt9_H_L 5wt9 97% -0.7834 6.5 4.0 -0.7754 -0.7843
A4DAB104_5ggr_A_B 5ggr 97% -0.7101 6.5 4.0 -0.6554 -0.7158