Fontolizumab

A4DAB119 | Phase-II
IFNG
G1 / None
PDL BioPharma
Phase-II
Whole mAb
HuZAF
—
Avg A4D Score
-0.7401
Score Range
-0.76 to -0.72
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB119_1t04_B_A 1t04 100% -0.7592 6.5 4.0 -0.2715 -0.8145
A4DAB119_1t3f_B_A 1t3f 100% -0.7384 6.5 4.0 -0.3067 -0.7873
A4DAB119_1t04_D_C 1t04 100% -0.7227 6.5 4.0 -0.2522 -0.776