Ibalizumab

A4DAB138 | Infectious diseases | Approved
CD4
G4 / IgG4
Biogen Idec TaiMed Biologics Theratechnologies
Approved
Whole mAb
Hu1A8 Hu5A8 TMB-355 TMB 355 TMC355 TNX-355 TNX 355 TNX355 Trogarzo
6
IMGT PubChem (3720768) PubChem (135347929) PubChem (160671956) PubChem (347911363) PubChem (381744890) PubChem (464013594) PubChem (468575068) PubChem (472213849) PubChem (472397460) PubChem (481155466) PubChem (483929330) PubChem (498129210) Thera-SAbDab YAbS
Avg A4D Score
-0.7457
Score Range
-0.77 to -0.73
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB138_7t0r_H_L 7t0r 100% -0.7373 6.5 4.0 -0.2653 -0.8039
A4DAB138_3o2d_H_L 3o2d 100% -0.7324 6.5 4.0 -0.2692 -0.7975
A4DAB138_7t0r_C_B 7t0r 100% -0.7673 6.5 4.0 -0.272 -0.8372