Idarucizumab

A4DAB140 | Cardiovascular / hemostasis disorders | Approved
Dabigatran
G1 / None
Boehringer Ingelheim
Approved
Fab
BI-655075 BI655075 BI 655075 Praxbind Prizbind
5.3-5.7
IMGT PubChem (252166510) PubChem (312467846) PubChem (347910427) PubChem (381127112) PubChem (469688591) PubChem (472264648) PubChem (472406919) PubChem (481101666) Thera-SAbDab YAbS
Avg A4D Score
-0.6076
Score Range
-0.63 to -0.58
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB140_4jn2_B_A 4jn2 100% -0.6317 6.5 9.0 N/A N/A
A4DAB140_4jn1_H_L 4jn1 100% -0.582 6.5 9.0 0.2663 -0.6997
A4DAB140_4jn2_H_L 4jn2 100% -0.6092 6.0 9.0 0.1737 -0.7187