Isatuximab

A4DAB145 | Cancer | Approved
ADPRC1/CD38
G1 / IgG1
ImmunoGen Huntsman Cancer Institute Roche Sanofi
Approved
Whole mAb
hu38SB19 SAR-650984 SAR650984 Sarclisa
6
IMGT PubChem (252827377) PubChem (312467981) PubChem (381127523) PubChem (404772261) PubChem (440801540) PubChem (461629177) PubChem (463589857) PubChem (472423060) PubChem (481155586) PubChem (483928573) PubChem (498152441) Thera-SAbDab YAbS
Avg A4D Score
-0.6616
Score Range
-0.66
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB145_4cmh_B_C 4cmh 100% -0.6616 6.5 4.0 -0.3725 -0.6972