Global Registry
A4D-Ab
Lebrikizumab
A4DAB153
|
Immune-mediated / inflammatory disorders
|
Approved
Target
IL13
Isotype / Subclass
G4 / IgG4
Company
Chugai Pharmaceutical
Comprehensive Clinical Research Network
Dermira
Genentech
Roche
Tanox
Clinical Status
Approved
Format
Whole mAb
Synonyms
DRM 06
DRM-06
DRM06
DRM 6
DRM-6
DRM6
LY 3650150
LY-3650150
LY3650150
MILR1444A
MILR-1444A
MILR 1444
ARG 3637
ARG-3637
ARG3637
RO 5490255
RO-5490255
RO5490255
TNX 650
TNX-650
TXN650
pH Formulation
5.4-6.0
IMGT
PubChem (135312293)
PubChem (160693416)
PubChem (223366019)
PubChem (347911256)
PubChem (472397316)
PubChem (481155563)
PubChem (498123574)
PubChem (505794595)
PubChem (508533758)
Thera-SAbDab
YAbS
Avg A4D Score
-0.7039
Score Range
-0.7
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
Export CSV
Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB153_4i77_H_L
4i77
100%
-0.7039
6.5
4.0
-0.4865
-0.7313