Lexatumumab

A4DAB154 | Phase-I
TNFRSF10B/CD262/DR5/TRAILR2
G1 / None
Cambridge Antibody Technology Human Genome Sciences
Phase-I
Whole mAb
HGS-ETR2
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IMGT PubChem (135349517) PubChem (160682607) PubChem (349353292) PubChem (404770338) PubChem (468892062) PubChem (472220702) PubChem (472399325) PubChem (474488735) PubChem (474489086) PubChem (480405382) PubChem (498126540) PubChem (505794780) PubChem (519927767) Thera-SAbDab YAbS
Avg A4D Score
-0.7408
Score Range
-0.74
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB154_4od2_B_A 4od2 96% -0.7408 6.5 9.0 -0.5736 -0.7632