Loncastuximab

A4DAB157 | Approved
CD19
G1 / None
ADC Therapeutics
Approved
Whole mAb ADC
ADCT-402 ADCT402 ADCT 402 MT-2111 MT2111 MT 2111 ZYNLONTA
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IMGT PubChem (381128134) PubChem (404719612) PubChem (472419163) PubChem (480403138) PubChem (481987996) PubChem (498149819) Thera-SAbDab YAbS
Avg A4D Score
-0.6826
Score Range
-0.7 to -0.66
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB157_6ani_I_M 6ani 99% -0.6617 6.5 4.0 -0.3228 -0.7011
A4DAB157_6ani_H_L 6ani 99% -0.7036 6.5 4.0 -0.3948 -0.7391