Lumretuzumab

A4DAB162 | Phase-I/II
ERBB3/HER3
G1 / None
Roche
Phase-I/II
Whole mAb
RG-7116 RG7116 RG 7116 RO-5479599 RO5479599 RO 5479599
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IMGT PubChem (318464639) PubChem (347911360) PubChem (381127466) PubChem (472407344) PubChem (474488740) PubChem (474489087) PubChem (498152580) PubChem (505795858) Thera-SAbDab YAbS
Avg A4D Score
-0.6726
Score Range
-0.67
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB162_4leo_A_B 4leo 100% -0.6726 6.5 4.0 -0.3011 -0.7244