Global Registry
A4D-Ab
Mosunetuzumab
A4DAB171
|
Cancer
|
Approved
Target
CD3E;MS4A1/CD20
Isotype / Subclass
G1 / IgG1
Company
Genentech
Clinical Status
Approved
Format
Bispecific mAb
Synonyms
BTCT 4465A
BTCT-4465A
RG7828
RG-7828
RG 7828
RO7030816
RO-7030816
RO 7030816
pH Formulation
—
IMGT
PubChem (381128154)
PubChem (404720369)
PubChem (404772861)
PubChem (472418928)
PubChem (479821089)
PubChem (481155458)
PubChem (483928771)
PubChem (498149583)
PubChem (505056118)
Thera-SAbDab
YAbS
Avg A4D Score
-0.6659
Score Range
-0.67
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB171_4k7p_Y_X
4k7p
98%
-0.6659
6.5
9.0
-0.0795
-0.7393