Onartuzumab

A4DAB193 | Cancer | Phase-III
MET/HGFR
G1 / IgG1
Chugai Pharmaceutical Genentech
Phase-III
Fab + di-Fc
5D5 MetMAb OA-5D5 PRO-143966 PRO 143966 PRO143996 RG-3638 RG3638 RG 3638 RO-5490258 RO5490258 RO 5490258
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IMGT PubChem (135324888) PubChem (160693418) PubChem (310264746) PubChem (347911234) PubChem (472390563) PubChem (472439123) PubChem (472441256) PubChem (505852702) PubChem (513905865) PubChem (519974962) Thera-SAbDab YAbS
Avg A4D Score
-0.7267
Score Range
-0.73
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB193_4k3j_H_L 4k3j 100% -0.7267 6.5 9.0 -0.3482 -0.7777