Panitumumab

A4DAB202 | Cancer | Approved
EGFR/ERBB1/HER1
G2 / IgG2
Amgen Grupo Espanol Multidisciplinario del Cancer Digestivo Netherlands Cancer Institute Novartis Takeda University of Texas M. D. Anderson Cancer Center Wissenschaftlicher Service Pharma
Approved
Whole mAb
ABX-EGF E7.6.3 Panitumab Vectibix
5.6-6.0
IMGT PubChem (46505063) PubChem (50070211) PubChem (91145251) PubChem (103771525) PubChem (135300957) PubChem (178103465) PubChem (329976994) PubChem (354355055) PubChem (387060159) PubChem (440790881) PubChem (441072529) PubChem (464013599) PubChem (468568986) PubChem (468800479) PubChem (472264659) PubChem (472422803) PubChem (481101778) PubChem (481155377) PubChem (485727436) PubChem (488413774) PubChem (508644826) PubChem (519825823) Thera-SAbDab YAbS
Avg A4D Score
-0.6884
Score Range
-0.71 to -0.67
Structures
4
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB202_5sx4_H_L 5sx4 100% -0.7129 6.5 4.0 -0.4499 -0.745
A4DAB202_5sx5_H_L 5sx5 100% -0.6716 6.5 4.0 -0.4548 -0.6983
A4DAB202_5sx5_J_K 5sx5 100% -0.674 6.5 4.0 -0.4715 -0.6989
A4DAB202_5sx4_J_I 5sx4 100% -0.6952 6.5 4.0 -0.409 -0.7306