Pateclizumab

A4DAB204 | Phase-II
LTA
G1 / None
Genentech
Phase-II
Whole mAb
MLTA3698A MLTA-3698A MLTA 3698A PRO283698 PRO-283698 PRO 283698 RG7416 RG-7416 RG 7416
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IMGT PubChem (160682612) PubChem (363894148) PubChem (381126562) PubChem (404772441) PubChem (472397390) PubChem (485483283) PubChem (485511861) PubChem (505854663) Thera-SAbDab YAbS
Avg A4D Score
-0.6907
Score Range
-0.71 to -0.67
Structures
5
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB204_4mxv_Y_X 4mxv 100% -0.6666 6.0 9.0 -0.0579 -0.7388
A4DAB204_4mxw_W_V 4mxw 100% -0.6704 6.0 9.0 -0.1091 -0.7373
A4DAB204_4mxv_H_L 4mxv 100% -0.7051 6.0 9.0 -0.0861 -0.7786
A4DAB204_4mxv_F_E 4mxv 100% -0.7062 6.5 9.0 -0.09 -0.7794
A4DAB204_4mxw_H_L 4mxw 100% -0.705 6.0 9.0 -0.1115 -0.7756