Pexelizumab

A4DAB208 | Phase-III

Target C5

Isotype / Subclass non-canonical / None

Company

Stanford University

Clinical Status Phase-III

Format scFv

Synonyms

5G1.1

pH Formulation —

IMGT PubChem (135313425) PubChem (160693004) PubChem (347909855) PubChem (472398204) PubChem (476264169) PubChem (476270780) PubChem (505856386) PubChem (513905956) Thera-SAbDab YAbS

Avg A4D Score

-0.7165

Score Range

-0.72 to -0.71

Structures

Avg. A4D Score per Structure

pH at Min / Max Aggregation Propensity

Structure ID	Source PDB	Seq. Identity	Avg. A4D Score	pH (Min Agg.)	pH (Max Agg.)	Score CDR	Score non-CDR
A4DAB208_5i5k_X_Y	5i5k	99%	-0.7228	6.5	4.0	-0.1203	-0.7995
A4DAB208_5i5k_H_L	5i5k	99%	-0.7101	6.5	4.0	-0.1817	-0.7774

Pexelizumab

Avg. A4D Score per Structure

pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2