Global Registry
A4D-Ab
Pinatuzumab
A4DAB209
|
Phase-II
Target
SIGLEC2/CD22
Isotype / Subclass
G1 / None
Company
Genentech
Clinical Status
Phase-II
Format
Whole mAb ADC
Synonyms
DCDT-2980S
DCDT29080S
DCDT 29080S
FCU-2703
FCU2703
FCU 2703
RG-7593
RG7593
RG 7593
RO-5541072
RO5541073
RO 5541073
pH Formulation
—
IMGT
PubChem (472435552)
PubChem (472440353)
PubChem (481155543)
PubChem (513253358)
Thera-SAbDab
YAbS
Avg A4D Score
-0.742
Score Range
-0.74
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
Export CSV
Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB209_6and_H_L
6and
99%
-0.742
6.5
4.0
-0.5974
-0.7595