Pulocimab

A4DAB213 | Cancer | Phase-III
KDR/CD309/VEGFR2
G1 / IgG1
Akeso Biopharma
Phase-III
Whole mAb
AK-109 AK109 AK 109
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IMGT PubChem (443565664) PubChem (461565711) PubChem (472424599) PubChem (480403215) PubChem (481988078) PubChem (513757576) Thera-SAbDab YAbS
Avg A4D Score
-0.635
Score Range
-0.65 to -0.62
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB213_3s36_H_L 3s36 99% -0.6234 6.5 4.0 -0.2834 -0.6614
A4DAB213_3s34_H_L 3s34 99% -0.6323 6.5 4.0 -0.2989 -0.6696
A4DAB213_3s37_H_L 3s37 99% -0.6493 6.5 4.0 -0.2896 -0.6902