Global Registry
A4D-Ab
Rozanolixizumab
A4DAB229
|
Immune-mediated / inflammatory disorders
|
Approved
Target
FCGRT/FcRn
Isotype / Subclass
G4 / IgG4
Company
UCB
Clinical Status
Approved
Format
Whole mAb
Synonyms
RYSTIGGO
UCB-7665
UCB7665
UCB 7665
pH Formulation
5.6
IMGT
PubChem (354702273)
PubChem (381127650)
PubChem (404719939)
PubChem (404772364)
PubChem (461629178)
PubChem (463599439)
PubChem (472410164)
PubChem (481155569)
PubChem (483928629)
PubChem (498151966)
PubChem (500132552)
Thera-SAbDab
YAbS
Avg A4D Score
-0.6976
Score Range
-0.7
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB229_6fgb_H_L
6fgb
100%
-0.6976
6.5
9.0
-0.3727
-0.7388