Spesolimab

A4DAB247 | Immune-mediated / inflammatory disorders | Approved
IL36RN
G1 / IgG1
Boehringer Ingelheim
Approved
Whole mAb
BI 655130 BI655130 BI-655130 SPEVIGO
5.0-6.0
IMGT PubChem (381128270) PubChem (404719820) PubChem (472319291) PubChem (472419473) PubChem (476262730) PubChem (476269338) PubChem (481155453) PubChem (483928962) PubChem (498147763) PubChem (500131935) Thera-SAbDab YAbS
Avg A4D Score
-0.7604
Score Range
-0.76
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB247_6u6u_H_L 6u6u 100% -0.7604 6.5 4.0 -0.3822 -0.8064