Talquetamab

A4DAB253 | Cancer | Approved
GPRC5D;CD3E
G4;G4 / IgG4
Genmab Janssen Research & Development
Approved
Bispecific mAb
JNJ 64407564 JNJ64407564 JNJ-64407564 JNJ-7564 JNJ7564 JNJ 7564 TALVEY
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IMGT PubChem (402425660) PubChem (440234734) PubChem (472420911) PubChem (473153828) PubChem (476262728) PubChem (476269336) PubChem (483928983) PubChem (498145303) PubChem (513906409) Thera-SAbDab YAbS
Avg A4D Score
-0.7404
Score Range
-0.74
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB253_9ima_C_D 9ima 100% -0.7404 6.5 4.0 -0.4909 -0.7692