Tilogotamab

A4DAB264 | Phase-I/II
TNFRSF10B/CD262/DR5/TRAILR2
G1 / None
Genmab
Phase-I/II
Whole mAb
GEN-1029 GEN1029 GEN 1029
—
IMGT PubChem (405023319) PubChem (472421517) PubChem (476262880) PubChem (476269424) Thera-SAbDab YAbS
Avg A4D Score
-0.7204
Score Range
-0.72 to -0.72
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB264_6t3j_H_I 6t3j 0% -0.7205 6.5 9.0 N/A N/A
A4DAB264_6t3j_C_D 6t3j 0% -0.7202 6.0 9.0 N/A N/A