Ustekinumab

A4DAB285 | Immune-mediated / inflammatory disorders | Approved

Target IL12B/CLMFp40

Isotype / Subclass G1 / IgG1

Company

Centocor Inc Janssen Biotech Medarex

Clinical Status Approved

Format Whole mAb

Synonyms

CNTO 1275 CNTO-1275 CNTO1275 TT-20 TT20 TT 20

pH Formulation 5.7-6.3

IMGT PubChem (103771533) PubChem (135302166) PubChem (178103467) PubChem (347910190) PubChem (349905851) PubChem (349984255) PubChem (354355053) PubChem (355433663) PubChem (377017835) PubChem (384647095) PubChem (385327552) PubChem (387060191) PubChem (440790971) PubChem (459142811) PubChem (469691025) PubChem (472217542) PubChem (472386393) PubChem (475546931) PubChem (477522405) PubChem (481101893) PubChem (481155329) PubChem (486347098) PubChem (488427388) PubChem (496156073) PubChem (497982764) PubChem (505187368) PubChem (519873421) Thera-SAbDab YAbS

Avg A4D Score

-0.7062

Score Range

-0.72 to -0.69

Structures

Structure ID	Source PDB	Seq. Identity	Avg. A4D Score	pH (Min Agg.)	pH (Max Agg.)	Score CDR	Score non-CDR
A4DAB285_3hmw_H_L	3hmw	100%	-0.7224	6.5	4.0	-0.297	-0.7731
A4DAB285_3hmx_H_L	3hmx	100%	-0.69	6.5	9.0	-0.2518	-0.7423