Global Registry
A4D-Ab
Ustekinumab
A4DAB285
|
Immune-mediated / inflammatory disorders
|
Approved
Target
IL12B/CLMFp40
Isotype / Subclass
G1 / IgG1
Clinical Status
Approved
Format
Whole mAb
Synonyms
CNTO 1275
CNTO-1275
CNTO1275
TT-20
TT20
TT 20
Company
Centocor Inc
Janssen Biotech
Medarex
pH Formulation
5.7-6.3
IMGT
PubChem
Thera-SAbDab
YAbS
Avg A4D Score
-0.7062
Score Range
-0.72 to -0.69
Structures
2
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB285_3hmw_H_L
3hmw
100%
-0.7224
6.5
4.0
-0.297
-0.7731
A4DAB285_3hmx_H_L
3hmx
100%
-0.69
6.5
9.0
-0.2518
-0.7423