Calculation Parameters
| Chain Sequence(s) |
VQLVQSGAEVKKPGASVKVSCKASGYEFTSYWIHWVRQAPGQGLEWMGNISPNSGSANYNEKFKSRVTMTRDTSTSTVYMELSSLRSEDTAVYYCAREGPYSYYPSREYYGSDLWGQGTLVTVSSASTKGPSVFPLAPCSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVEIVLTQSPATLSLSPGERATLSCRASQSISNNLHWYQQKPGQAPRLLIYYTSRSVSGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCGQNNEWPEVFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 2 | V | A | 0.9452 | Aggregation-prone |
| 3 | Q | A | -0.4831 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | -0.0007 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.6443 | Soluble |
| 8 | G | A | -0.6267 | Soluble |
| 9 | A | A | -0.2964 | Soluble |
| 11 | E | A | -0.6946 | Soluble |
| 12 | V | A | -0.2480 | Soluble |
| 13 | K | A | -1.4205 | Soluble |
| 14 | K | A | -2.2787 | Soluble |
| 15 | P | A | -1.9687 | Soluble |
| 16 | G | A | -1.3837 | Soluble |
| 17 | A | A | -1.0423 | Soluble |
| 18 | S | A | -1.2330 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -2.0148 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.5853 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -1.0197 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.5207 | Soluble |
| 27 | G | A | -0.3141 | Soluble |
| 28 | Y | A | -0.6614 | Soluble |
| 29 | E | A | -1.6824 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | -0.9476 | Soluble |
| 36 | S | A | -0.5438 | Soluble |
| 37 | Y | A | -0.2513 | Soluble |
| 38 | W | A | 0.1648 | Aggregation-prone |
| 39 | I | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.5797 | Soluble |
| 45 | A | A | -0.9473 | Soluble |
| 46 | P | A | -0.8030 | Soluble |
| 47 | G | A | -1.2357 | Soluble |
| 48 | Q | A | -1.7310 | Soluble |
| 49 | G | A | -1.1020 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.5811 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | N | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | -0.6644 | Soluble |
| 58 | P | A | 0.0000 | Buried |
| 59 | N | A | -1.5568 | Soluble |
| 62 | S | A | -1.0189 | Soluble |
| 63 | G | A | -0.9658 | Soluble |
| 64 | S | A | -0.7567 | Soluble |
| 65 | A | A | -0.5663 | Soluble |
| 66 | N | A | -0.9188 | Soluble |
| 67 | Y | A | -1.2325 | Soluble |
| 68 | N | A | -1.8736 | Soluble |
| 69 | E | A | -3.1827 | Soluble |
| 70 | K | A | -3.0062 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | K | A | -2.6978 | Soluble |
| 74 | S | A | -1.6286 | Soluble |
| 75 | R | A | -1.3201 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.7960 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.4514 | Soluble |
| 80 | R | A | -1.1134 | Soluble |
| 81 | D | A | -1.2875 | Soluble |
| 82 | T | A | -0.9285 | Soluble |
| 83 | S | A | -0.5623 | Soluble |
| 84 | T | A | -0.6705 | Soluble |
| 85 | S | A | -0.9690 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | V | A | 0.0000 | Buried |
| 88 | Y | A | -0.5733 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.3664 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | S | A | -0.9036 | Soluble |
| 93 | S | A | -0.9117 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.2074 | Soluble |
| 96 | S | A | -1.9482 | Soluble |
| 97 | E | A | -2.2272 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.7867 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2369 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.2853 | Soluble |
| 107 | E | A | 0.0000 | Buried |
| 108 | G | A | 0.0000 | Buried |
| 109 | P | A | -0.1148 | Soluble |
| 110 | Y | A | 0.7534 | Aggregation-prone |
| 111 | S | A | 0.9011 | Aggregation-prone |
| 111A | Y | A | 1.8299 | Aggregation-prone |
| 111B | Y | A | 1.7880 | Aggregation-prone |
| 111C | P | A | 0.1917 | Aggregation-prone |
| 112C | S | A | -0.9392 | Soluble |
| 112B | R | A | -2.4355 | Soluble |
| 112A | E | A | -1.7662 | Soluble |
| 112 | Y | A | -0.5901 | Soluble |
| 113 | Y | A | 0.0817 | Aggregation-prone |
| 114 | G | A | 0.0000 | Buried |
| 115 | S | A | 0.0000 | Buried |
| 116 | D | A | -1.0375 | Soluble |
| 117 | L | A | -0.5564 | Soluble |
| 118 | W | A | -0.7694 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.4015 | Soluble |
| 121 | G | A | -0.6370 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | L | A | 0.0451 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.3006 | Soluble |
| 128 | S | A | -1.1478 | Soluble |
| 129 | A | A | -0.6634 | Soluble |
| 130 | S | A | -0.7299 | Soluble |
| 131 | T | A | -0.6854 | Soluble |
| 132 | K | A | -1.1952 | Soluble |
| 133 | G | A | -1.3842 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.3580 | Soluble |
| 136 | V | A | -0.4514 | Soluble |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -0.7518 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | 0.1262 | Aggregation-prone |
| 141 | P | A | 0.0624 | Aggregation-prone |
| 142 | C | A | -0.3313 | Soluble |
| 143 | S | A | -0.3528 | Soluble |
| 144 | T | A | -0.8438 | Soluble |
| 145 | S | A | -1.1792 | Soluble |
| 146 | E | A | -2.1214 | Soluble |
| 147 | S | A | -1.2963 | Soluble |
| 148 | T | A | -0.9124 | Soluble |
| 149 | A | A | 0.0000 | Buried |
| 150 | A | A | 0.0000 | Buried |
| 151 | L | A | 0.0000 | Buried |
| 152 | G | A | 0.0000 | Buried |
| 153 | C | A | 0.0000 | Buried |
| 154 | L | A | 0.0000 | Buried |
| 155 | V | A | 0.0000 | Buried |
| 156 | K | A | 0.0000 | Buried |
| 157 | D | A | -0.5139 | Soluble |
| 158 | Y | A | 0.0000 | Buried |
| 159 | F | A | 0.0000 | Buried |
| 160 | P | A | 0.0000 | Buried |
| 161 | E | A | -0.4297 | Soluble |
| 162 | P | A | -0.8370 | Soluble |
| 163 | V | A | -0.8572 | Soluble |
| 164 | T | A | -0.7431 | Soluble |
| 165 | V | A | -0.4785 | Soluble |
| 166 | S | A | -0.5768 | Soluble |
| 167 | W | A | 0.0000 | Buried |
| 168 | N | A | -1.0233 | Soluble |
| 169 | S | A | -0.7844 | Soluble |
| 170 | G | A | -0.6138 | Soluble |
| 171 | A | A | -0.2941 | Soluble |
| 172 | L | A | -0.1505 | Soluble |
| 173 | T | A | -0.2211 | Soluble |
| 174 | S | A | -0.2132 | Soluble |
| 175 | G | A | -0.2409 | Soluble |
| 176 | V | A | 0.1725 | Aggregation-prone |
| 177 | H | A | 0.0000 | Buried |
| 178 | T | A | 0.0237 | Aggregation-prone |
| 179 | F | A | 0.0000 | Buried |
| 180 | P | A | -0.2690 | Soluble |
| 181 | A | A | 0.2395 | Aggregation-prone |
| 182 | V | A | 0.6507 | Aggregation-prone |
| 183 | L | A | 1.2326 | Aggregation-prone |
| 184 | Q | A | 0.2982 | Aggregation-prone |
| 185 | S | A | -0.0443 | Soluble |
| 186 | S | A | -0.2083 | Soluble |
| 187 | G | A | 0.0254 | Aggregation-prone |
| 188 | L | A | 0.0742 | Aggregation-prone |
| 189 | Y | A | 0.0000 | Buried |
| 190 | S | A | 0.0000 | Buried |
| 191 | L | A | 0.0000 | Buried |
| 192 | S | A | 0.0000 | Buried |
| 193 | S | A | 0.0000 | Buried |
| 194 | V | A | 0.0000 | Buried |
| 195 | V | A | 0.0000 | Buried |
| 196 | T | A | -0.1173 | Soluble |
| 197 | V | A | 0.0000 | Buried |
| 198 | P | A | -0.5429 | Soluble |
| 199 | S | A | -0.6571 | Soluble |
| 200 | S | A | -0.6541 | Soluble |
| 201 | S | A | -0.5552 | Soluble |
| 202 | L | A | -0.0826 | Soluble |
| 203 | G | A | -0.6317 | Soluble |
| 204 | T | A | -0.8341 | Soluble |
| 205 | K | A | -1.4619 | Soluble |
| 206 | T | A | -1.0351 | Soluble |
| 207 | Y | A | 0.0000 | Buried |
| 208 | T | A | 0.0000 | Buried |
| 209 | C | A | 0.0000 | Buried |
| 210 | N | A | -1.7543 | Soluble |
| 211 | V | A | 0.0000 | Buried |
| 212 | D | A | -2.3995 | Soluble |
| 213 | H | A | 0.0000 | Buried |
| 214 | K | A | -2.8674 | Soluble |
| 215 | P | A | -1.6443 | Soluble |
| 216 | S | A | -1.8616 | Soluble |
| 217 | N | A | -2.6422 | Soluble |
| 218 | T | A | -2.1760 | Soluble |
| 219 | K | A | -2.8102 | Soluble |
| 220 | V | A | -1.7482 | Soluble |
| 221 | D | A | -2.7316 | Soluble |
| 222 | K | A | -1.9912 | Soluble |
| 223 | R | A | -2.2401 | Soluble |
| 224 | V | A | -0.5823 | Soluble |
| 1 | E | B | -1.6156 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.7753 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.5746 | Soluble |
| 6 | Q | B | -0.6734 | Soluble |
| 7 | S | B | -0.6639 | Soluble |
| 8 | P | B | -0.2813 | Soluble |
| 9 | A | B | -0.2527 | Soluble |
| 10 | T | B | -0.1740 | Soluble |
| 11 | L | B | -0.0567 | Soluble |
| 12 | S | B | -0.4316 | Soluble |
| 13 | L | B | -0.8350 | Soluble |
| 14 | S | B | -1.2368 | Soluble |
| 15 | P | B | -1.5707 | Soluble |
| 16 | G | B | -1.5867 | Soluble |
| 17 | E | B | -2.0353 | Soluble |
| 18 | R | B | -2.4183 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.6206 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.8189 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.1852 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.9265 | Soluble |
| 27 | Q | B | -1.7084 | Soluble |
| 28 | S | B | -1.3932 | Soluble |
| 29 | I | B | 0.0000 | Buried |
| 36 | S | B | -1.3572 | Soluble |
| 37 | N | B | -1.3148 | Soluble |
| 38 | N | B | 0.0000 | Buried |
| 39 | L | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.3902 | Soluble |
| 46 | P | B | -1.3132 | Soluble |
| 47 | G | B | -1.4551 | Soluble |
| 48 | Q | B | -2.0693 | Soluble |
| 49 | A | B | -1.3279 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.5123 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | -0.2628 | Soluble |
| 56 | Y | B | -0.4271 | Soluble |
| 57 | T | B | 0.0000 | Buried |
| 65 | S | B | -0.8604 | Soluble |
| 66 | R | B | -1.0026 | Soluble |
| 67 | S | B | -0.6417 | Soluble |
| 68 | V | B | -0.3048 | Soluble |
| 69 | S | B | -0.5063 | Soluble |
| 70 | G | B | -0.4067 | Soluble |
| 71 | I | B | -0.1646 | Soluble |
| 72 | P | B | -0.1866 | Soluble |
| 74 | A | B | -0.1761 | Soluble |
| 75 | R | B | -0.6775 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.5336 | Soluble |
| 78 | G | B | -0.5589 | Soluble |
| 79 | S | B | -0.7890 | Soluble |
| 80 | G | B | -1.1487 | Soluble |
| 83 | S | B | -0.9404 | Soluble |
| 84 | G | B | -1.4153 | Soluble |
| 85 | T | B | -1.7458 | Soluble |
| 86 | D | B | -1.9916 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.7321 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.6276 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.2984 | Soluble |
| 93 | S | B | -1.6060 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -1.8695 | Soluble |
| 96 | P | B | -1.5695 | Soluble |
| 97 | E | B | -2.2496 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -0.5705 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.0566 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | G | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | N | B | 0.0000 | Buried |
| 108 | N | B | -1.3374 | Soluble |
| 109 | E | B | -1.3179 | Soluble |
| 114 | W | B | -0.5566 | Soluble |
| 115 | P | B | -0.9187 | Soluble |
| 116 | E | B | 0.0000 | Buried |
| 117 | V | B | 0.0444 | Aggregation-prone |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.6052 | Soluble |
| 121 | G | B | -0.5962 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -0.3708 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | 0.0000 | Buried |
| 126 | I | B | -0.6389 | Soluble |
| 127 | K | B | -1.2922 | Soluble |
| 128 | R | B | -0.9949 | Soluble |
| 129 | T | B | -0.1342 | Soluble |
| 130 | V | B | 0.2360 | Aggregation-prone |
| 131 | A | B | 0.0335 | Aggregation-prone |
| 132 | A | B | -0.1556 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1953 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0403 | Aggregation-prone |
| 137 | I | B | 0.0583 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.2292 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.5917 | Soluble |
| 142 | D | B | -3.0036 | Soluble |
| 143 | E | B | -3.2516 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.3162 | Soluble |
| 146 | K | B | -2.9408 | Soluble |
| 147 | S | B | -1.8438 | Soluble |
| 148 | G | B | -1.2717 | Soluble |
| 149 | T | B | -1.0616 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.7809 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.6048 | Soluble |
| 162 | R | B | -2.7160 | Soluble |
| 163 | E | B | -3.0893 | Soluble |
| 164 | A | B | -2.2735 | Soluble |
| 165 | K | B | -2.4543 | Soluble |
| 166 | V | B | -1.3985 | Soluble |
| 167 | Q | B | -1.2830 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.8489 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.8633 | Soluble |
| 172 | N | B | -1.5699 | Soluble |
| 173 | A | B | -0.4186 | Soluble |
| 174 | L | B | 0.2061 | Aggregation-prone |
| 175 | Q | B | -0.6369 | Soluble |
| 176 | S | B | -0.8726 | Soluble |
| 177 | G | B | -1.3373 | Soluble |
| 178 | N | B | -1.7108 | Soluble |
| 179 | S | B | -1.5374 | Soluble |
| 180 | Q | B | -1.4176 | Soluble |
| 181 | E | B | -1.5389 | Soluble |
| 182 | S | B | -0.6689 | Soluble |
| 183 | V | B | -0.6874 | Soluble |
| 184 | T | B | -0.9515 | Soluble |
| 185 | E | B | -1.7811 | Soluble |
| 186 | Q | B | -1.5365 | Soluble |
| 187 | D | B | -1.7131 | Soluble |
| 188 | S | B | -1.8065 | Soluble |
| 189 | K | B | -2.1747 | Soluble |
| 190 | D | B | -1.5710 | Soluble |
| 191 | S | B | -1.5048 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7124 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.6992 | Soluble |
| 201 | L | B | -0.8782 | Soluble |
| 202 | S | B | -1.0913 | Soluble |
| 203 | K | B | -2.0380 | Soluble |
| 204 | A | B | -1.8902 | Soluble |
| 205 | D | B | -2.7093 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.2996 | Soluble |
| 208 | K | B | -3.5892 | Soluble |
| 209 | H | B | -2.9618 | Soluble |
| 210 | K | B | -3.2050 | Soluble |
| 211 | V | B | -1.3749 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -1.1657 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.3518 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.5232 | Soluble |
| 220 | G | B | -0.4322 | Soluble |
| 221 | L | B | -0.2083 | Soluble |
| 222 | S | B | -0.4361 | Soluble |
| 223 | S | B | -0.4438 | Soluble |
| 224 | P | B | -0.6166 | Soluble |
| 225 | V | B | -0.0955 | Soluble |
| 226 | T | B | -0.5703 | Soluble |
| 227 | K | B | -0.6649 | Soluble |
| 228 | S | B | -0.4933 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -1.7685 | Soluble |
| 231 | R | B | -2.3270 | Soluble |
| 232 | G | B | -1.8480 | Soluble |
| 233 | E | B | -2.2120 | Soluble |
| 234 | C | B | -0.7793 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.703 | 2.5018 | CSV PDB |
| 4.5 | -0.7482 | 2.5018 | CSV PDB |
| 5.0 | -0.8024 | 2.5018 | CSV PDB |
| 5.5 | -0.8546 | 2.5018 | CSV PDB |
| 6.0 | -0.8927 | 2.5018 | CSV PDB |
| 6.5 | -0.9067 | 2.5018 | CSV PDB |
| 7.0 | -0.8958 | 2.5016 | CSV PDB |
| 7.5 | -0.8682 | 2.5011 | CSV PDB |
| 8.0 | -0.8316 | 2.4995 | CSV PDB |
| 8.5 | -0.7895 | 2.4944 | CSV PDB |
| 9.0 | -0.7426 | 2.4785 | CSV PDB |