Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYSISWVRQAPGQGLEWMGWISVYNGNTNYAQKFQGRVTMTTDTSTSTAYLELRSLRSDDTAVYYCARDPIAAGYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCEIVLTQSPGTLSLSPGERATLSCRASQSVSSTYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | B | -1.4256 | Soluble |
| 2 | V | B | -0.8292 | Soluble |
| 3 | Q | B | -0.9972 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | -0.0096 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.5905 | Soluble |
| 8 | G | B | -0.3555 | Soluble |
| 9 | A | B | 0.0101 | Aggregation-prone |
| 11 | E | B | -0.2286 | Soluble |
| 12 | V | B | 0.1333 | Aggregation-prone |
| 13 | K | B | -1.2789 | Soluble |
| 14 | K | B | -2.0874 | Soluble |
| 15 | P | B | -2.1176 | Soluble |
| 16 | G | B | -1.6433 | Soluble |
| 17 | A | B | -1.3035 | Soluble |
| 18 | S | B | -1.4515 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | K | B | -2.0765 | Soluble |
| 21 | V | B | 0.0000 | Buried |
| 22 | S | B | -0.7328 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | K | B | -1.3241 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.9189 | Soluble |
| 27 | G | B | -0.9399 | Soluble |
| 28 | Y | B | -0.2743 | Soluble |
| 29 | T | B | -0.0420 | Soluble |
| 30 | F | B | 0.0000 | Buried |
| 35 | T | B | 0.2382 | Aggregation-prone |
| 36 | S | B | 0.2658 | Aggregation-prone |
| 37 | Y | B | 0.6762 | Aggregation-prone |
| 38 | S | B | 0.0630 | Aggregation-prone |
| 39 | I | B | 0.0000 | Buried |
| 40 | S | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -0.5296 | Soluble |
| 45 | A | B | -0.9159 | Soluble |
| 46 | P | B | -0.9426 | Soluble |
| 47 | G | B | -1.2489 | Soluble |
| 48 | Q | B | -1.8769 | Soluble |
| 49 | G | B | -1.3123 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -0.8199 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | M | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | W | B | -0.2912 | Soluble |
| 56 | I | B | 0.0000 | Buried |
| 57 | S | B | -0.5868 | Soluble |
| 58 | V | B | 0.0000 | Buried |
| 59 | Y | B | 0.3398 | Aggregation-prone |
| 62 | N | B | -1.2891 | Soluble |
| 63 | G | B | -1.3437 | Soluble |
| 64 | N | B | -1.8136 | Soluble |
| 65 | T | B | -1.1634 | Soluble |
| 66 | N | B | -1.1359 | Soluble |
| 67 | Y | B | -1.2347 | Soluble |
| 68 | A | B | -1.6652 | Soluble |
| 69 | Q | B | -2.5900 | Soluble |
| 70 | K | B | -2.6863 | Soluble |
| 71 | F | B | 0.0000 | Buried |
| 72 | Q | B | -2.4553 | Soluble |
| 74 | G | B | -1.6256 | Soluble |
| 75 | R | B | -1.5504 | Soluble |
| 76 | V | B | 0.0000 | Buried |
| 77 | T | B | -0.8204 | Soluble |
| 78 | M | B | 0.0000 | Buried |
| 79 | T | B | -0.5969 | Soluble |
| 80 | T | B | -0.5233 | Soluble |
| 81 | D | B | -0.7427 | Soluble |
| 82 | T | B | -0.3154 | Soluble |
| 83 | S | B | -0.4802 | Soluble |
| 84 | T | B | -0.6898 | Soluble |
| 85 | S | B | -0.7756 | Soluble |
| 86 | T | B | 0.0000 | Buried |
| 87 | A | B | 0.0000 | Buried |
| 88 | Y | B | -0.6917 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | E | B | -1.4794 | Soluble |
| 91 | L | B | 0.0000 | Buried |
| 92 | R | B | -1.5725 | Soluble |
| 93 | S | B | -1.3609 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -2.9475 | Soluble |
| 96 | S | B | -2.3270 | Soluble |
| 97 | D | B | -2.4815 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.8403 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.3872 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | 0.0000 | Buried |
| 107 | D | B | 0.0045 | Aggregation-prone |
| 108 | P | B | 0.0316 | Aggregation-prone |
| 109 | I | B | 0.3191 | Aggregation-prone |
| 114 | A | B | 0.1084 | Aggregation-prone |
| 115 | A | B | 0.1240 | Aggregation-prone |
| 116 | G | B | -0.2284 | Soluble |
| 117 | Y | B | 0.0437 | Aggregation-prone |
| 118 | W | B | -0.1660 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -0.9912 | Soluble |
| 121 | G | B | -0.3764 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | L | B | 0.7045 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | -0.4966 | Soluble |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -1.3499 | Soluble |
| 128 | S | B | -1.0740 | Soluble |
| 129 | A | B | -0.6094 | Soluble |
| 130 | S | B | -0.7250 | Soluble |
| 131 | T | B | -0.8133 | Soluble |
| 132 | K | B | -1.3788 | Soluble |
| 133 | G | B | -1.4578 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.3744 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -0.9137 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -1.1833 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | 0.0000 | Buried |
| 143 | S | B | -0.6962 | Soluble |
| 144 | K | B | -0.7534 | Soluble |
| 145 | S | B | 0.0000 | Buried |
| 146 | T | B | -0.6037 | Soluble |
| 147 | S | B | -0.7306 | Soluble |
| 148 | G | B | -0.8770 | Soluble |
| 149 | G | B | -0.9128 | Soluble |
| 150 | T | B | -0.6387 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.3926 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.9174 | Soluble |
| 164 | P | B | -1.0866 | Soluble |
| 165 | V | B | -0.8741 | Soluble |
| 166 | T | B | -0.7083 | Soluble |
| 167 | V | B | -0.2759 | Soluble |
| 168 | S | B | -0.1597 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.3614 | Soluble |
| 171 | S | B | -0.3737 | Soluble |
| 172 | G | B | -0.2675 | Soluble |
| 173 | A | B | 0.0903 | Aggregation-prone |
| 174 | L | B | 0.5952 | Aggregation-prone |
| 175 | T | B | 0.1077 | Aggregation-prone |
| 176 | S | B | -0.0994 | Soluble |
| 177 | G | B | -0.0949 | Soluble |
| 178 | V | B | 0.1071 | Aggregation-prone |
| 179 | H | B | -0.2764 | Soluble |
| 180 | T | B | -0.1006 | Soluble |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.3700 | Soluble |
| 183 | A | B | 0.1510 | Aggregation-prone |
| 184 | V | B | 0.6237 | Aggregation-prone |
| 185 | L | B | 1.4034 | Aggregation-prone |
| 186 | Q | B | 0.4557 | Aggregation-prone |
| 187 | S | B | 0.0138 | Aggregation-prone |
| 188 | S | B | -0.1399 | Soluble |
| 189 | G | B | 0.0842 | Aggregation-prone |
| 190 | L | B | 0.0191 | Aggregation-prone |
| 191 | Y | B | 0.0000 | Buried |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.1790 | Aggregation-prone |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1539 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.6127 | Soluble |
| 201 | S | B | -0.6587 | Soluble |
| 202 | S | B | -0.5594 | Soluble |
| 203 | S | B | -0.5581 | Soluble |
| 204 | L | B | -0.8450 | Soluble |
| 205 | G | B | -0.8451 | Soluble |
| 206 | T | B | -0.5809 | Soluble |
| 207 | Q | B | -0.7279 | Soluble |
| 208 | T | B | -0.8048 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -0.6665 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | 0.0000 | Buried |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -2.0393 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.8914 | Soluble |
| 217 | P | B | -1.7830 | Soluble |
| 218 | S | B | -1.9260 | Soluble |
| 219 | N | B | -2.6381 | Soluble |
| 220 | T | B | -2.1985 | Soluble |
| 221 | K | B | -2.6155 | Soluble |
| 222 | V | B | -1.1593 | Soluble |
| 223 | D | B | -1.6869 | Soluble |
| 224 | K | B | -1.4914 | Soluble |
| 225 | K | B | -1.6896 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.5025 | Soluble |
| 228 | P | B | -2.0254 | Soluble |
| 229 | K | B | -2.1022 | Soluble |
| 230 | S | B | -1.0796 | Soluble |
| 231 | C | B | -0.5910 | Soluble |
| 1 | E | A | -1.6385 | Soluble |
| 2 | I | A | 0.0000 | Buried |
| 3 | V | A | 0.5365 | Aggregation-prone |
| 4 | L | A | 0.0000 | Buried |
| 5 | T | A | -0.7832 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.8842 | Soluble |
| 8 | P | A | -0.4855 | Soluble |
| 9 | G | A | -0.8181 | Soluble |
| 10 | T | A | -0.3572 | Soluble |
| 11 | L | A | -0.0742 | Soluble |
| 12 | S | A | -0.4061 | Soluble |
| 13 | L | A | -0.7828 | Soluble |
| 14 | S | A | -1.3725 | Soluble |
| 15 | P | A | -2.0787 | Soluble |
| 16 | G | A | -2.4394 | Soluble |
| 17 | E | A | -2.8351 | Soluble |
| 18 | R | A | -3.1766 | Soluble |
| 19 | A | A | 0.0000 | Buried |
| 20 | T | A | -0.5456 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.9458 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.3950 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.1094 | Soluble |
| 27 | Q | A | -1.8085 | Soluble |
| 28 | S | A | -1.4557 | Soluble |
| 29 | V | A | 0.0000 | Buried |
| 30 | S | A | -0.2489 | Soluble |
| 36 | S | A | -0.3246 | Soluble |
| 37 | T | A | 0.1527 | Aggregation-prone |
| 38 | Y | A | 0.6684 | Aggregation-prone |
| 39 | L | A | 0.0000 | Buried |
| 40 | A | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | 0.0000 | Buried |
| 45 | K | A | -1.2199 | Soluble |
| 46 | P | A | -1.2324 | Soluble |
| 47 | G | A | -1.2679 | Soluble |
| 48 | Q | A | -1.8584 | Soluble |
| 49 | A | A | -1.2627 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | R | A | -1.6601 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | 0.1868 | Aggregation-prone |
| 56 | G | A | 0.0658 | Aggregation-prone |
| 57 | A | A | 0.0000 | Buried |
| 65 | S | A | -0.5731 | Soluble |
| 66 | S | A | -0.6154 | Soluble |
| 67 | R | A | -1.3773 | Soluble |
| 68 | A | A | -0.7571 | Soluble |
| 69 | T | A | -0.5619 | Soluble |
| 70 | G | A | -0.8796 | Soluble |
| 71 | I | A | 0.0000 | Buried |
| 72 | P | A | -1.3716 | Soluble |
| 74 | D | A | -2.4020 | Soluble |
| 75 | R | A | -2.1274 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -0.9190 | Soluble |
| 78 | G | A | -0.4923 | Soluble |
| 79 | S | A | -0.6877 | Soluble |
| 80 | G | A | -1.1180 | Soluble |
| 83 | S | A | -1.1225 | Soluble |
| 84 | G | A | -1.3168 | Soluble |
| 85 | T | A | -1.9027 | Soluble |
| 86 | D | A | -2.3182 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.7924 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.8284 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -2.3909 | Soluble |
| 93 | R | A | -3.5509 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | E | A | -2.7931 | Soluble |
| 96 | P | A | -1.8960 | Soluble |
| 97 | E | A | -2.3220 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | F | A | -0.5214 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.0233 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | Q | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | Y | A | 0.1444 | Aggregation-prone |
| 108 | G | A | -0.1439 | Soluble |
| 109 | S | A | -0.5744 | Soluble |
| 114 | S | A | -0.8091 | Soluble |
| 115 | P | A | -0.9699 | Soluble |
| 116 | R | A | -0.3259 | Soluble |
| 117 | T | A | -0.2188 | Soluble |
| 118 | F | A | 0.0405 | Aggregation-prone |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.3627 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -0.4550 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | E | A | 0.0000 | Buried |
| 126 | I | A | -0.5176 | Soluble |
| 127 | K | A | -0.6791 | Soluble |
| 128 | R | A | -0.5296 | Soluble |
| 129 | T | A | 0.3045 | Aggregation-prone |
| 130 | V | A | 0.9921 | Aggregation-prone |
| 131 | A | A | 0.2773 | Aggregation-prone |
| 132 | A | A | 0.0488 | Aggregation-prone |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.1895 | Soluble |
| 135 | V | A | 0.0000 | Buried |
| 136 | F | A | 0.0000 | Buried |
| 137 | I | A | 0.0000 | Buried |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.3236 | Soluble |
| 140 | P | A | -0.5212 | Soluble |
| 141 | S | A | -1.2971 | Soluble |
| 142 | D | A | -2.5843 | Soluble |
| 143 | E | A | -2.1854 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -1.9331 | Soluble |
| 146 | K | A | -2.5511 | Soluble |
| 147 | S | A | -1.5802 | Soluble |
| 148 | G | A | -1.2250 | Soluble |
| 149 | T | A | -1.0938 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -0.8119 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.4693 | Soluble |
| 162 | R | A | -2.8451 | Soluble |
| 163 | E | A | -3.1835 | Soluble |
| 164 | A | A | -2.3305 | Soluble |
| 165 | K | A | -2.3825 | Soluble |
| 166 | V | A | -0.9600 | Soluble |
| 167 | Q | A | -0.4974 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.6746 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -1.6776 | Soluble |
| 172 | N | A | -1.5072 | Soluble |
| 173 | A | A | -0.3513 | Soluble |
| 174 | L | A | 0.4808 | Aggregation-prone |
| 175 | Q | A | -0.2836 | Soluble |
| 176 | S | A | -0.4808 | Soluble |
| 177 | G | A | -0.8511 | Soluble |
| 178 | N | A | -0.7434 | Soluble |
| 179 | S | A | -0.9823 | Soluble |
| 180 | Q | A | -1.1422 | Soluble |
| 181 | E | A | -1.6610 | Soluble |
| 182 | S | A | -0.9232 | Soluble |
| 183 | V | A | -0.8677 | Soluble |
| 184 | T | A | -1.2478 | Soluble |
| 185 | E | A | -2.2629 | Soluble |
| 186 | Q | A | -1.8468 | Soluble |
| 187 | D | A | -1.9352 | Soluble |
| 188 | S | A | -1.7289 | Soluble |
| 189 | K | A | -2.2411 | Soluble |
| 190 | D | A | -1.6711 | Soluble |
| 191 | S | A | -1.5677 | Soluble |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | 0.0000 | Buried |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.4238 | Soluble |
| 201 | L | A | -0.8114 | Soluble |
| 202 | S | A | -1.1862 | Soluble |
| 203 | K | A | -2.1712 | Soluble |
| 204 | A | A | -2.1128 | Soluble |
| 205 | D | A | -3.1832 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.9696 | Soluble |
| 208 | K | A | -3.8698 | Soluble |
| 209 | H | A | -3.3396 | Soluble |
| 210 | K | A | -3.2887 | Soluble |
| 211 | V | A | -1.4926 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.6992 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.1170 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.6644 | Soluble |
| 220 | G | A | -0.2278 | Soluble |
| 221 | L | A | -0.1044 | Soluble |
| 222 | S | A | -0.4047 | Soluble |
| 223 | S | A | -0.4022 | Soluble |
| 224 | P | A | -0.5840 | Soluble |
| 225 | V | A | 0.0724 | Aggregation-prone |
| 226 | T | A | -0.3705 | Soluble |
| 227 | K | A | -0.7222 | Soluble |
| 228 | S | A | -0.4590 | Soluble |
| 229 | F | A | 0.0000 | Buried |
| 230 | N | A | -1.6162 | Soluble |
| 231 | R | A | -2.1183 | Soluble |
| 232 | G | A | -1.8538 | Soluble |
| 233 | E | A | -2.1222 | Soluble |
| 234 | C | A | -1.0429 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7031 | 1.7039 | CSV PDB |
| 4.5 | -0.744 | 1.6781 | CSV PDB |
| 5.0 | -0.7914 | 1.6448 | CSV PDB |
| 5.5 | -0.836 | 1.6081 | CSV PDB |
| 6.0 | -0.8669 | 1.5719 | CSV PDB |
| 6.5 | -0.8757 | 1.5401 | CSV PDB |
| 7.0 | -0.8622 | 1.5155 | CSV PDB |
| 7.5 | -0.8338 | 1.4975 | CSV PDB |
| 8.0 | -0.7971 | 1.4837 | CSV PDB |
| 8.5 | -0.7542 | 1.4734 | CSV PDB |
| 9.0 | -0.7059 | 1.467 | CSV PDB |