Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTWIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGFMFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKDIQMTQSPSSLSASVGDRVTITCRASQDIPRRISGYVAWYQQKPGKAPKLLIYWGSYLYSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.1703 | Soluble |
| 2 | V | A | -1.3866 | Soluble |
| 3 | Q | A | -1.4731 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.1512 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.5602 | Soluble |
| 8 | G | A | -0.8185 | Soluble |
| 9 | G | A | -0.4904 | Soluble |
| 11 | G | A | -0.2819 | Soluble |
| 12 | L | A | -0.1368 | Soluble |
| 13 | V | A | 0.0000 | Buried |
| 14 | Q | A | -1.6594 | Soluble |
| 15 | P | A | -1.7438 | Soluble |
| 16 | G | A | -1.4736 | Soluble |
| 17 | G | A | -1.1528 | Soluble |
| 18 | S | A | -1.0904 | Soluble |
| 19 | L | A | -1.0603 | Soluble |
| 20 | R | A | -1.9134 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.4918 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.3641 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.1603 | Soluble |
| 27 | G | A | -1.4635 | Soluble |
| 28 | F | A | -1.5829 | Soluble |
| 29 | N | A | -2.5648 | Soluble |
| 30 | I | A | 0.0000 | Buried |
| 35 | K | A | -2.9887 | Soluble |
| 36 | D | A | -2.6028 | Soluble |
| 37 | T | A | 0.0000 | Buried |
| 38 | W | A | 0.0649 | Aggregation-prone |
| 39 | I | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.8148 | Soluble |
| 45 | A | A | -1.1950 | Soluble |
| 46 | P | A | -0.9841 | Soluble |
| 47 | G | A | -1.4624 | Soluble |
| 48 | K | A | -2.3835 | Soluble |
| 49 | G | A | -1.6457 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.1047 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | A | A | 0.0000 | Buried |
| 55 | R | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | Y | A | -0.3547 | Soluble |
| 58 | P | A | -1.1102 | Soluble |
| 59 | T | A | -1.3080 | Soluble |
| 62 | N | A | -1.1625 | Soluble |
| 63 | G | A | -0.4726 | Soluble |
| 64 | Y | A | 0.4577 | Aggregation-prone |
| 65 | T | A | -0.4388 | Soluble |
| 66 | R | A | -1.9292 | Soluble |
| 67 | Y | A | -1.7450 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | D | A | -2.5884 | Soluble |
| 70 | S | A | -1.6899 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.7084 | Soluble |
| 74 | G | A | -1.6158 | Soluble |
| 75 | R | A | 0.0000 | Buried |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -1.0340 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.1734 | Soluble |
| 80 | A | A | -0.8627 | Soluble |
| 81 | D | A | -1.4690 | Soluble |
| 82 | T | A | -1.9010 | Soluble |
| 83 | S | A | -1.6159 | Soluble |
| 84 | K | A | -2.2368 | Soluble |
| 85 | N | A | -1.8788 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | 0.0000 | Buried |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.2150 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -1.3402 | Soluble |
| 93 | S | A | -1.2432 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.4328 | Soluble |
| 96 | A | A | -1.7938 | Soluble |
| 97 | E | A | -2.2745 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.7603 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2393 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | S | A | 0.0000 | Buried |
| 106 | R | A | -0.0225 | Soluble |
| 107 | W | A | 0.0000 | Buried |
| 108 | G | A | 0.0000 | Buried |
| 109 | G | A | 0.3181 | Aggregation-prone |
| 110 | F | A | 1.7987 | Aggregation-prone |
| 111 | M | A | 1.3549 | Aggregation-prone |
| 112 | F | A | 1.4529 | Aggregation-prone |
| 113 | Y | A | 0.9918 | Aggregation-prone |
| 114 | A | A | 0.0000 | Buried |
| 115 | M | A | 0.0000 | Buried |
| 116 | D | A | -0.0877 | Soluble |
| 117 | Y | A | -0.0496 | Soluble |
| 118 | W | A | -0.4154 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.5011 | Soluble |
| 121 | G | A | -0.6851 | Soluble |
| 122 | T | A | -0.1382 | Soluble |
| 123 | L | A | 0.1821 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.4937 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.0020 | Soluble |
| 128 | S | A | -0.7108 | Soluble |
| 129 | A | A | -0.4689 | Soluble |
| 130 | S | A | -0.5963 | Soluble |
| 131 | T | A | -0.8938 | Soluble |
| 132 | K | A | -1.1444 | Soluble |
| 133 | G | A | -1.3434 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.5600 | Soluble |
| 136 | V | A | -0.6518 | Soluble |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.2449 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.8327 | Soluble |
| 141 | P | A | -0.8973 | Soluble |
| 142 | S | A | 0.0000 | Buried |
| 143 | S | A | -1.3480 | Soluble |
| 144 | K | A | -1.9032 | Soluble |
| 145 | S | A | -1.1966 | Soluble |
| 146 | T | A | -0.8318 | Soluble |
| 147 | S | A | -0.6073 | Soluble |
| 148 | G | A | -0.8041 | Soluble |
| 149 | G | A | -0.8540 | Soluble |
| 150 | T | A | -0.5965 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | -0.2378 | Soluble |
| 159 | D | A | -0.3970 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.5606 | Soluble |
| 164 | P | A | -0.6513 | Soluble |
| 165 | V | A | -0.6810 | Soluble |
| 166 | T | A | -0.5882 | Soluble |
| 167 | V | A | -0.3762 | Soluble |
| 168 | S | A | -0.4129 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.7464 | Soluble |
| 171 | S | A | -0.6731 | Soluble |
| 172 | G | A | -0.5816 | Soluble |
| 173 | A | A | -0.2505 | Soluble |
| 174 | L | A | -0.0091 | Soluble |
| 175 | T | A | -0.1863 | Soluble |
| 176 | S | A | -0.1950 | Soluble |
| 177 | G | A | -0.2345 | Soluble |
| 178 | V | A | 0.1683 | Aggregation-prone |
| 179 | H | A | -0.3118 | Soluble |
| 180 | T | A | 0.0459 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.2660 | Soluble |
| 183 | A | A | 0.2970 | Aggregation-prone |
| 184 | V | A | 0.6727 | Aggregation-prone |
| 185 | L | A | 1.3223 | Aggregation-prone |
| 186 | Q | A | 0.3245 | Aggregation-prone |
| 187 | S | A | -0.0442 | Soluble |
| 188 | S | A | -0.1910 | Soluble |
| 189 | G | A | 0.0699 | Aggregation-prone |
| 190 | L | A | 0.2278 | Aggregation-prone |
| 191 | Y | A | 0.5256 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1286 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.5986 | Soluble |
| 201 | S | A | -0.5350 | Soluble |
| 202 | S | A | -0.5362 | Soluble |
| 203 | S | A | -0.5831 | Soluble |
| 204 | L | A | -0.6963 | Soluble |
| 205 | G | A | -1.2290 | Soluble |
| 206 | T | A | -0.8961 | Soluble |
| 207 | Q | A | -1.2130 | Soluble |
| 208 | T | A | -1.0151 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.1362 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.4646 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -2.0668 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.7802 | Soluble |
| 217 | P | A | -1.6114 | Soluble |
| 218 | S | A | -1.8490 | Soluble |
| 219 | N | A | -2.6175 | Soluble |
| 220 | T | A | -2.1105 | Soluble |
| 221 | K | A | -2.7328 | Soluble |
| 222 | V | A | -1.5708 | Soluble |
| 223 | D | A | -2.5031 | Soluble |
| 224 | K | A | -2.1387 | Soluble |
| 225 | K | A | -2.2404 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.6676 | Soluble |
| 228 | P | A | -1.7315 | Soluble |
| 229 | K | A | -2.3178 | Soluble |
| 1 | D | B | -2.1281 | Soluble |
| 2 | I | B | -1.6839 | Soluble |
| 3 | Q | B | -1.8911 | Soluble |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -1.2345 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.8298 | Soluble |
| 8 | P | B | -0.5205 | Soluble |
| 9 | S | B | -0.8968 | Soluble |
| 10 | S | B | -0.7972 | Soluble |
| 11 | L | B | -0.5091 | Soluble |
| 12 | S | B | -0.8833 | Soluble |
| 13 | A | B | -0.9238 | Soluble |
| 14 | S | B | -0.8069 | Soluble |
| 15 | V | B | -0.0466 | Soluble |
| 16 | G | B | -0.8181 | Soluble |
| 17 | D | B | -1.8276 | Soluble |
| 18 | R | B | -2.3077 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.6344 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.6481 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.2031 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -2.1503 | Soluble |
| 27 | Q | B | -2.7737 | Soluble |
| 28 | D | B | -2.7514 | Soluble |
| 29 | I | B | 0.0000 | Buried |
| 30 | P | B | -1.7976 | Soluble |
| 31 | R | B | -2.7707 | Soluble |
| 34 | R | B | -2.2234 | Soluble |
| 35 | I | B | -0.1280 | Soluble |
| 36 | S | B | -0.1397 | Soluble |
| 37 | G | B | 0.0000 | Buried |
| 38 | Y | B | 0.8079 | Aggregation-prone |
| 39 | V | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.6309 | Soluble |
| 46 | P | B | -1.3324 | Soluble |
| 47 | G | B | -1.6868 | Soluble |
| 48 | K | B | -2.3426 | Soluble |
| 49 | A | B | -1.4583 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.3723 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 1.1136 | Aggregation-prone |
| 56 | W | B | 1.0567 | Aggregation-prone |
| 57 | G | B | 0.3854 | Aggregation-prone |
| 65 | S | B | 0.5765 | Aggregation-prone |
| 66 | Y | B | 1.5933 | Aggregation-prone |
| 67 | L | B | 1.1682 | Aggregation-prone |
| 68 | Y | B | 0.4861 | Aggregation-prone |
| 69 | S | B | -0.0708 | Soluble |
| 70 | G | B | -0.4726 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | P | B | -0.3475 | Soluble |
| 74 | S | B | -0.4036 | Soluble |
| 75 | R | B | -0.7195 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.0509 | Soluble |
| 78 | G | B | 0.0325 | Aggregation-prone |
| 79 | S | B | -0.4617 | Soluble |
| 80 | G | B | -1.0118 | Soluble |
| 83 | S | B | -0.8755 | Soluble |
| 84 | G | B | -1.6824 | Soluble |
| 85 | T | B | -1.8095 | Soluble |
| 86 | D | B | -1.5530 | Soluble |
| 87 | F | B | -0.9399 | Soluble |
| 88 | T | B | -0.5981 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.6125 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.3412 | Soluble |
| 93 | S | B | -1.1320 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -0.9069 | Soluble |
| 96 | P | B | -1.6496 | Soluble |
| 97 | E | B | -2.1913 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | -0.8681 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | Y | B | 0.4282 | Aggregation-prone |
| 109 | T | B | -0.1531 | Soluble |
| 114 | T | B | -0.3216 | Soluble |
| 115 | P | B | -0.6318 | Soluble |
| 116 | P | B | 0.0000 | Buried |
| 117 | T | B | -0.3764 | Soluble |
| 118 | F | B | -0.4591 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.8054 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.6036 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -1.3398 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.1787 | Soluble |
| 128 | R | B | -0.7015 | Soluble |
| 129 | T | B | 0.2363 | Aggregation-prone |
| 130 | V | B | 1.0156 | Aggregation-prone |
| 131 | A | B | 0.2885 | Aggregation-prone |
| 132 | A | B | 0.0521 | Aggregation-prone |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1162 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | -0.0202 | Soluble |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.6153 | Soluble |
| 140 | P | B | -0.7384 | Soluble |
| 141 | S | B | -1.8457 | Soluble |
| 142 | D | B | -3.0057 | Soluble |
| 143 | E | B | -3.0909 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.2407 | Soluble |
| 146 | K | B | -2.8222 | Soluble |
| 147 | S | B | -1.7502 | Soluble |
| 148 | G | B | -1.3051 | Soluble |
| 149 | T | B | -1.1307 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.8866 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.6152 | Soluble |
| 162 | R | B | -2.8990 | Soluble |
| 163 | E | B | -3.2460 | Soluble |
| 164 | A | B | -2.4041 | Soluble |
| 165 | K | B | -2.4063 | Soluble |
| 166 | V | B | 0.0000 | Buried |
| 167 | Q | B | -0.8479 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.7538 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.8234 | Soluble |
| 172 | N | B | -1.5425 | Soluble |
| 173 | A | B | -0.3208 | Soluble |
| 174 | L | B | 0.6504 | Aggregation-prone |
| 175 | Q | B | -0.3872 | Soluble |
| 176 | S | B | -0.6618 | Soluble |
| 177 | G | B | -1.3501 | Soluble |
| 178 | N | B | -1.7493 | Soluble |
| 179 | S | B | -1.5149 | Soluble |
| 180 | Q | B | -1.3781 | Soluble |
| 181 | E | B | -1.5179 | Soluble |
| 182 | S | B | -0.8087 | Soluble |
| 183 | V | B | -0.9573 | Soluble |
| 184 | T | B | -1.1953 | Soluble |
| 185 | E | B | -2.2767 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.1271 | Soluble |
| 188 | S | B | -2.3003 | Soluble |
| 189 | K | B | -2.6578 | Soluble |
| 190 | D | B | -1.9649 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7345 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.6960 | Soluble |
| 201 | L | B | -0.7485 | Soluble |
| 202 | S | B | -0.9300 | Soluble |
| 203 | K | B | -1.8977 | Soluble |
| 204 | A | B | -1.6948 | Soluble |
| 205 | D | B | -2.3372 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.2251 | Soluble |
| 208 | K | B | -3.3831 | Soluble |
| 209 | H | B | -2.7464 | Soluble |
| 210 | K | B | -2.3091 | Soluble |
| 211 | V | B | -0.8861 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | -0.8183 | Soluble |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -1.2466 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.3062 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.5964 | Soluble |
| 220 | G | B | -0.2117 | Soluble |
| 221 | L | B | -0.1371 | Soluble |
| 222 | S | B | -0.4450 | Soluble |
| 223 | S | B | -0.4135 | Soluble |
| 224 | P | B | -0.6186 | Soluble |
| 225 | V | B | -0.1371 | Soluble |
| 226 | T | B | -0.5730 | Soluble |
| 227 | K | B | -0.7662 | Soluble |
| 228 | S | B | -0.7774 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -1.3069 | Soluble |
| 231 | R | B | -1.5579 | Soluble |
| 232 | G | B | -1.0237 | Soluble |
| 233 | E | B | -0.8935 | Soluble |
| 234 | C | B | -0.4986 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7314 | 4.8317 | CSV PDB |
| 4.5 | -0.7741 | 4.7888 | CSV PDB |
| 5.0 | -0.8229 | 4.7374 | CSV PDB |
| 5.5 | -0.8685 | 4.6826 | CSV PDB |
| 6.0 | -0.9 | 4.6266 | CSV PDB |
| 6.5 | -0.9084 | 4.5703 | CSV PDB |
| 7.0 | -0.8938 | 4.514 | CSV PDB |
| 7.5 | -0.8639 | 4.4582 | CSV PDB |
| 8.0 | -0.8254 | 4.4042 | CSV PDB |
| 8.5 | -0.7801 | 4.3548 | CSV PDB |
| 9.0 | -0.7281 | 4.3159 | CSV PDB |