Calculation Parameters
| Chain Sequence(s) |
VQLVQSGAEVKKPGASVKVSCKASGFSLSSYGVSWVRQAPGQGLEWMGAISYDGITYYASWAKSRVTMTRDTSTSTVYMELSSLRSEDTAVYYCARGDYYDDYVYVYALDIWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKEIVLTQSPGTLSLSPGERATLSCQASQSISTALAWYQQKPGQAPRLLIYAASTLASGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQGYSSSNLDNVFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 2 | V | A | 1.0836 | Aggregation-prone |
| 3 | Q | A | -0.4177 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | -0.2124 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.5954 | Soluble |
| 8 | G | A | -0.4350 | Soluble |
| 9 | A | A | -0.0724 | Soluble |
| 11 | E | A | -0.3385 | Soluble |
| 12 | V | A | 0.0900 | Aggregation-prone |
| 13 | K | A | -1.3378 | Soluble |
| 14 | K | A | -2.3378 | Soluble |
| 15 | P | A | -2.2305 | Soluble |
| 16 | G | A | -1.5688 | Soluble |
| 17 | A | A | -1.2483 | Soluble |
| 18 | S | A | -1.3148 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -1.9797 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.5992 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -0.9398 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.2477 | Soluble |
| 27 | G | A | 0.0424 | Aggregation-prone |
| 28 | F | A | 0.1520 | Aggregation-prone |
| 29 | S | A | -0.0829 | Soluble |
| 30 | L | A | 0.0000 | Buried |
| 35 | S | A | -0.7631 | Soluble |
| 36 | S | A | -0.4131 | Soluble |
| 37 | Y | A | -0.0846 | Soluble |
| 38 | G | A | 0.0000 | Buried |
| 39 | V | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | -0.4774 | Soluble |
| 44 | Q | A | -0.7425 | Soluble |
| 45 | A | A | -1.0344 | Soluble |
| 46 | P | A | -0.8573 | Soluble |
| 47 | G | A | -1.2929 | Soluble |
| 48 | Q | A | -1.8149 | Soluble |
| 49 | G | A | -1.2554 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.2677 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | A | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | 0.0000 | Buried |
| 58 | Y | A | -0.2562 | Soluble |
| 59 | D | A | -1.1686 | Soluble |
| 63 | G | A | -0.0314 | Soluble |
| 64 | I | A | 1.5035 | Aggregation-prone |
| 65 | T | A | 0.8752 | Aggregation-prone |
| 66 | Y | A | 0.3045 | Aggregation-prone |
| 67 | Y | A | -0.6756 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | S | A | -1.3454 | Soluble |
| 70 | W | A | -0.7928 | Soluble |
| 71 | A | A | 0.0000 | Buried |
| 72 | K | A | -1.8166 | Soluble |
| 74 | S | A | -1.0820 | Soluble |
| 75 | R | A | -0.9136 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.7278 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.2062 | Soluble |
| 80 | R | A | -0.9380 | Soluble |
| 81 | D | A | -1.3235 | Soluble |
| 82 | T | A | -0.8660 | Soluble |
| 83 | S | A | -0.6697 | Soluble |
| 84 | T | A | -0.6647 | Soluble |
| 85 | S | A | -0.8024 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | V | A | 0.0000 | Buried |
| 88 | Y | A | -0.6091 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.3176 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | S | A | -1.0159 | Soluble |
| 93 | S | A | -1.1304 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.8160 | Soluble |
| 96 | S | A | -2.2290 | Soluble |
| 97 | E | A | -2.4140 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.8143 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2221 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | G | A | 0.0000 | Buried |
| 108 | D | A | -0.1738 | Soluble |
| 109 | Y | A | 0.3592 | Aggregation-prone |
| 110 | Y | A | 0.2092 | Aggregation-prone |
| 111 | D | A | -0.0743 | Soluble |
| 111A | D | A | -0.7123 | Soluble |
| 111B | Y | A | 1.2434 | Aggregation-prone |
| 112B | V | A | 1.9230 | Aggregation-prone |
| 112A | Y | A | 1.7296 | Aggregation-prone |
| 112 | V | A | 0.0000 | Buried |
| 113 | Y | A | 0.0000 | Buried |
| 114 | A | A | 0.0000 | Buried |
| 115 | L | A | 0.0000 | Buried |
| 116 | D | A | -0.5039 | Soluble |
| 117 | I | A | -0.0290 | Soluble |
| 118 | W | A | -0.3660 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.2379 | Soluble |
| 121 | G | A | -0.6231 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | L | A | 0.2657 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.3361 | Soluble |
| 128 | S | A | -1.1348 | Soluble |
| 129 | A | A | -0.6661 | Soluble |
| 130 | S | A | -0.7375 | Soluble |
| 131 | T | A | -0.8307 | Soluble |
| 132 | K | A | -1.5507 | Soluble |
| 133 | G | A | -1.5613 | Soluble |
| 134 | P | A | -0.7778 | Soluble |
| 135 | S | A | -0.6067 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.3114 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.9282 | Soluble |
| 141 | P | A | -0.7889 | Soluble |
| 142 | C | A | -0.9310 | Soluble |
| 143 | S | A | -1.3070 | Soluble |
| 144 | R | A | -2.1555 | Soluble |
| 145 | S | A | -1.4536 | Soluble |
| 146 | T | A | -1.0913 | Soluble |
| 147 | S | A | -1.1743 | Soluble |
| 148 | E | A | -1.8844 | Soluble |
| 149 | S | A | -1.0356 | Soluble |
| 150 | T | A | -0.8914 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.5028 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.4955 | Soluble |
| 164 | P | A | -0.8348 | Soluble |
| 165 | V | A | -0.8069 | Soluble |
| 166 | T | A | -0.6675 | Soluble |
| 167 | V | A | -0.4277 | Soluble |
| 168 | S | A | -0.5385 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -1.0420 | Soluble |
| 171 | S | A | -0.8015 | Soluble |
| 172 | G | A | -0.6135 | Soluble |
| 173 | A | A | -0.2792 | Soluble |
| 174 | L | A | -0.1100 | Soluble |
| 175 | T | A | -0.2075 | Soluble |
| 176 | S | A | -0.1960 | Soluble |
| 177 | G | A | -0.2810 | Soluble |
| 178 | V | A | 0.1490 | Aggregation-prone |
| 179 | H | A | -0.3267 | Soluble |
| 180 | T | A | 0.0120 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.4853 | Soluble |
| 183 | A | A | 0.0695 | Aggregation-prone |
| 184 | V | A | 0.2326 | Aggregation-prone |
| 185 | L | A | 1.0473 | Aggregation-prone |
| 186 | Q | A | 0.1068 | Aggregation-prone |
| 187 | S | A | -0.0909 | Soluble |
| 188 | S | A | -0.2318 | Soluble |
| 189 | G | A | 0.0150 | Aggregation-prone |
| 190 | L | A | -0.0759 | Soluble |
| 191 | Y | A | 0.0000 | Buried |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1197 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.6578 | Soluble |
| 201 | S | A | -0.9773 | Soluble |
| 202 | S | A | -0.7121 | Soluble |
| 203 | S | A | -0.6995 | Soluble |
| 204 | L | A | -0.8584 | Soluble |
| 205 | G | A | -1.0377 | Soluble |
| 206 | T | A | -0.8463 | Soluble |
| 207 | K | A | -1.5427 | Soluble |
| 208 | T | A | -1.4118 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | T | A | -1.9242 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.8144 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | D | A | -2.1163 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.7683 | Soluble |
| 217 | P | A | -1.5878 | Soluble |
| 218 | S | A | -1.9113 | Soluble |
| 219 | N | A | -2.6044 | Soluble |
| 220 | T | A | -2.1863 | Soluble |
| 221 | K | A | -2.7916 | Soluble |
| 222 | V | A | -1.9380 | Soluble |
| 223 | D | A | -2.8771 | Soluble |
| 224 | K | A | -2.4073 | Soluble |
| 225 | R | A | -2.9702 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.9604 | Soluble |
| 228 | S | A | -2.0105 | Soluble |
| 229 | K | A | -2.2581 | Soluble |
| 1 | E | B | -2.1624 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.3143 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.1884 | Soluble |
| 6 | Q | B | -0.5098 | Soluble |
| 7 | S | B | -0.6847 | Soluble |
| 8 | P | B | -0.5874 | Soluble |
| 9 | G | B | -0.8066 | Soluble |
| 10 | T | B | -0.4839 | Soluble |
| 11 | L | B | -0.2595 | Soluble |
| 12 | S | B | -0.3848 | Soluble |
| 13 | L | B | -0.6901 | Soluble |
| 14 | S | B | -1.0907 | Soluble |
| 15 | P | B | -1.7667 | Soluble |
| 16 | G | B | -2.0249 | Soluble |
| 17 | E | B | -2.6240 | Soluble |
| 18 | R | B | -3.0435 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.5463 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.6945 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | Q | B | -1.1963 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.8501 | Soluble |
| 27 | Q | B | -1.4576 | Soluble |
| 28 | S | B | -1.0462 | Soluble |
| 29 | I | B | 0.0000 | Buried |
| 36 | S | B | -0.5547 | Soluble |
| 37 | T | B | -0.3630 | Soluble |
| 38 | A | B | 0.0000 | Buried |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.5147 | Soluble |
| 46 | P | B | -1.4490 | Soluble |
| 47 | G | B | -1.3222 | Soluble |
| 48 | Q | B | -2.0419 | Soluble |
| 49 | A | B | -1.2856 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.2327 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.3021 | Aggregation-prone |
| 56 | A | B | 0.0466 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.2144 | Soluble |
| 66 | T | B | 0.1813 | Aggregation-prone |
| 67 | L | B | 0.2119 | Aggregation-prone |
| 68 | A | B | -0.1811 | Soluble |
| 69 | S | B | -0.3103 | Soluble |
| 70 | G | B | -0.5977 | Soluble |
| 71 | I | B | -0.5282 | Soluble |
| 72 | P | B | -0.9807 | Soluble |
| 74 | D | B | -2.0896 | Soluble |
| 75 | R | B | -1.9842 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.6940 | Soluble |
| 78 | G | B | -0.2679 | Soluble |
| 79 | S | B | -0.7526 | Soluble |
| 80 | G | B | -1.0750 | Soluble |
| 83 | S | B | -0.9865 | Soluble |
| 84 | G | B | -1.1371 | Soluble |
| 85 | T | B | -1.5711 | Soluble |
| 86 | D | B | -2.3039 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.7271 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.8371 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.5017 | Soluble |
| 93 | R | B | -3.3527 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -2.4636 | Soluble |
| 96 | P | B | -1.7224 | Soluble |
| 97 | E | B | -2.2626 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -0.6613 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.1034 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | G | B | 0.0000 | Buried |
| 108 | Y | B | 0.9645 | Aggregation-prone |
| 109 | S | B | 0.0454 | Aggregation-prone |
| 110 | S | B | -0.3965 | Soluble |
| 112 | S | B | -1.0653 | Soluble |
| 113 | N | B | -2.1636 | Soluble |
| 114 | L | B | 0.0000 | Buried |
| 115 | D | B | -1.9869 | Soluble |
| 116 | N | B | -1.2206 | Soluble |
| 117 | V | B | 0.0000 | Buried |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.8126 | Soluble |
| 121 | G | B | -0.7121 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -0.5987 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | 0.0000 | Buried |
| 126 | I | B | -0.5225 | Soluble |
| 127 | K | B | -1.0761 | Soluble |
| 128 | R | B | -0.8918 | Soluble |
| 129 | T | B | -0.0629 | Soluble |
| 130 | V | B | 0.3001 | Aggregation-prone |
| 131 | A | B | 0.0802 | Aggregation-prone |
| 132 | A | B | -0.1611 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1591 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | -0.2428 | Soluble |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.3546 | Soluble |
| 140 | P | B | -0.8120 | Soluble |
| 141 | S | B | -1.6742 | Soluble |
| 142 | D | B | -3.0465 | Soluble |
| 143 | E | B | -3.2349 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.1966 | Soluble |
| 146 | K | B | -2.9475 | Soluble |
| 147 | S | B | -1.8329 | Soluble |
| 148 | G | B | -1.3658 | Soluble |
| 149 | T | B | -1.0271 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.8739 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.6710 | Soluble |
| 162 | R | B | -2.9184 | Soluble |
| 163 | E | B | -3.1680 | Soluble |
| 164 | A | B | -2.2497 | Soluble |
| 165 | K | B | -2.3665 | Soluble |
| 166 | V | B | -0.9241 | Soluble |
| 167 | Q | B | -0.5390 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.6225 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.8761 | Soluble |
| 172 | N | B | -1.4572 | Soluble |
| 173 | A | B | -0.3733 | Soluble |
| 174 | L | B | 0.5350 | Aggregation-prone |
| 175 | Q | B | -0.1615 | Soluble |
| 176 | S | B | -0.4255 | Soluble |
| 177 | G | B | -0.9699 | Soluble |
| 178 | N | B | -0.8461 | Soluble |
| 179 | S | B | -1.3554 | Soluble |
| 180 | Q | B | -1.8906 | Soluble |
| 181 | E | B | -1.9686 | Soluble |
| 182 | S | B | 0.0000 | Buried |
| 183 | V | B | -0.8505 | Soluble |
| 184 | T | B | -1.2094 | Soluble |
| 185 | E | B | -2.2773 | Soluble |
| 186 | Q | B | -1.8451 | Soluble |
| 187 | D | B | -1.9359 | Soluble |
| 188 | S | B | -1.9001 | Soluble |
| 189 | K | B | -2.2157 | Soluble |
| 190 | D | B | -1.6541 | Soluble |
| 191 | S | B | -1.5851 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7834 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.4079 | Soluble |
| 201 | L | B | -0.4588 | Soluble |
| 202 | S | B | -0.9299 | Soluble |
| 203 | K | B | -2.1204 | Soluble |
| 204 | A | B | -1.7230 | Soluble |
| 205 | D | B | -2.0661 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.4229 | Soluble |
| 208 | K | B | -3.3591 | Soluble |
| 209 | H | B | -2.5127 | Soluble |
| 210 | K | B | -2.4099 | Soluble |
| 211 | V | B | -1.2887 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.6214 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.1833 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.7681 | Soluble |
| 220 | G | B | -0.4557 | Soluble |
| 221 | L | B | -0.2649 | Soluble |
| 222 | S | B | -0.4688 | Soluble |
| 223 | S | B | -0.4090 | Soluble |
| 224 | P | B | -0.5310 | Soluble |
| 225 | V | B | 0.0476 | Aggregation-prone |
| 226 | T | B | -0.4529 | Soluble |
| 227 | K | B | -0.7603 | Soluble |
| 228 | S | B | -0.6776 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -1.6157 | Soluble |
| 231 | R | B | -2.0002 | Soluble |
| 232 | G | B | -1.7294 | Soluble |
| 233 | E | B | -2.0622 | Soluble |
| 234 | C | B | -0.8099 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6969 | 3.1227 | CSV PDB |
| 4.5 | -0.7455 | 3.036 | CSV PDB |
| 5.0 | -0.8037 | 2.9256 | CSV PDB |
| 5.5 | -0.8606 | 2.8044 | CSV PDB |
| 6.0 | -0.9042 | 2.6793 | CSV PDB |
| 6.5 | -0.9259 | 2.5529 | CSV PDB |
| 7.0 | -0.9251 | 2.4265 | CSV PDB |
| 7.5 | -0.9087 | 2.3007 | CSV PDB |
| 8.0 | -0.8833 | 2.1776 | CSV PDB |
| 8.5 | -0.8515 | 2.0619 | CSV PDB |
| 9.0 | -0.8129 | 1.9645 | CSV PDB |