Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTWIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGMMFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSDIQMTQSPSSLSASVGDRVTITCRASQDIPRSISGYVAWYQQKPGKAPKLLIYWGSYLYSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.1440 | Soluble |
| 2 | V | A | -1.3046 | Soluble |
| 3 | Q | A | -1.2377 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.9486 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.4362 | Soluble |
| 8 | G | A | -0.9137 | Soluble |
| 9 | G | A | -0.6747 | Soluble |
| 11 | G | A | -0.3305 | Soluble |
| 12 | L | A | -0.0424 | Soluble |
| 13 | V | A | -0.6013 | Soluble |
| 14 | Q | A | -1.5628 | Soluble |
| 15 | P | A | -1.6688 | Soluble |
| 16 | G | A | -1.3932 | Soluble |
| 17 | G | A | -1.0714 | Soluble |
| 18 | S | A | -1.2698 | Soluble |
| 19 | L | A | -1.1209 | Soluble |
| 20 | R | A | -2.0408 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.4082 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.1279 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.0572 | Soluble |
| 27 | G | A | -1.4053 | Soluble |
| 28 | F | A | -1.4845 | Soluble |
| 29 | N | A | -2.4695 | Soluble |
| 30 | I | A | 0.0000 | Buried |
| 35 | K | A | -3.0423 | Soluble |
| 36 | D | A | -2.7366 | Soluble |
| 37 | T | A | 0.0000 | Buried |
| 38 | W | A | -0.1355 | Soluble |
| 39 | I | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.7765 | Soluble |
| 45 | A | A | -1.1879 | Soluble |
| 46 | P | A | -1.1484 | Soluble |
| 47 | G | A | -1.4623 | Soluble |
| 48 | K | A | -2.3674 | Soluble |
| 49 | G | A | -1.6498 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.0738 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | A | A | 0.0000 | Buried |
| 55 | R | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | Y | A | -0.3783 | Soluble |
| 58 | P | A | -1.2658 | Soluble |
| 59 | T | A | -1.5139 | Soluble |
| 62 | N | A | -1.3516 | Soluble |
| 63 | G | A | -0.5976 | Soluble |
| 64 | Y | A | 0.3162 | Aggregation-prone |
| 65 | T | A | -0.0310 | Soluble |
| 66 | R | A | -0.7921 | Soluble |
| 67 | Y | A | -1.2454 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | D | A | -2.5908 | Soluble |
| 70 | S | A | -1.6254 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.7540 | Soluble |
| 74 | G | A | -1.8268 | Soluble |
| 75 | R | A | -1.6069 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -0.9802 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.2447 | Soluble |
| 80 | A | A | -1.0437 | Soluble |
| 81 | D | A | -1.5969 | Soluble |
| 82 | T | A | -1.9599 | Soluble |
| 83 | S | A | -1.6590 | Soluble |
| 84 | K | A | -2.2499 | Soluble |
| 85 | N | A | -1.9246 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | 0.0000 | Buried |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.2902 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -1.4486 | Soluble |
| 93 | S | A | -1.3014 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.4264 | Soluble |
| 96 | A | A | -1.7712 | Soluble |
| 97 | E | A | -2.2831 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.7609 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2254 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | S | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | W | A | 0.0000 | Buried |
| 108 | G | A | 0.0000 | Buried |
| 109 | G | A | -0.0259 | Soluble |
| 110 | M | A | 0.9899 | Aggregation-prone |
| 111 | M | A | 1.0249 | Aggregation-prone |
| 112 | F | A | 1.4383 | Aggregation-prone |
| 113 | Y | A | 1.0366 | Aggregation-prone |
| 114 | A | A | 0.0000 | Buried |
| 115 | M | A | 0.0000 | Buried |
| 116 | D | A | -0.0235 | Soluble |
| 117 | Y | A | 0.0080 | Aggregation-prone |
| 118 | W | A | -0.2509 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.2682 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | -0.0449 | Soluble |
| 123 | L | A | -0.0015 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.4772 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.7474 | Soluble |
| 128 | S | A | -0.6618 | Soluble |
| 129 | A | A | -0.4241 | Soluble |
| 130 | S | A | -0.5466 | Soluble |
| 131 | T | A | -0.6088 | Soluble |
| 132 | K | A | -1.1958 | Soluble |
| 133 | G | A | -1.3868 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.4068 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.2195 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.2902 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.8096 | Soluble |
| 143 | S | A | -0.2942 | Soluble |
| 144 | T | A | -0.5150 | Soluble |
| 145 | S | A | -0.6548 | Soluble |
| 146 | G | A | -0.8770 | Soluble |
| 147 | G | A | -0.9259 | Soluble |
| 148 | T | A | -0.6847 | Soluble |
| 149 | A | A | 0.0000 | Buried |
| 150 | A | A | 0.0000 | Buried |
| 151 | L | A | 0.0000 | Buried |
| 152 | G | A | 0.0000 | Buried |
| 153 | C | A | 0.0000 | Buried |
| 154 | L | A | 0.0000 | Buried |
| 155 | V | A | 0.0000 | Buried |
| 156 | K | A | 0.0000 | Buried |
| 157 | D | A | -0.4005 | Soluble |
| 158 | Y | A | 0.0000 | Buried |
| 159 | F | A | 0.0000 | Buried |
| 160 | P | A | 0.0000 | Buried |
| 161 | E | A | -0.6841 | Soluble |
| 162 | P | A | -0.8095 | Soluble |
| 163 | V | A | 0.0000 | Buried |
| 164 | T | A | -0.5763 | Soluble |
| 165 | V | A | -0.3852 | Soluble |
| 166 | S | A | -0.3477 | Soluble |
| 167 | W | A | 0.0000 | Buried |
| 168 | N | A | -0.7475 | Soluble |
| 169 | S | A | -0.6797 | Soluble |
| 170 | G | A | -0.5728 | Soluble |
| 171 | A | A | -0.2487 | Soluble |
| 172 | L | A | -0.0051 | Soluble |
| 173 | T | A | -0.1808 | Soluble |
| 174 | S | A | -0.2031 | Soluble |
| 175 | G | A | -0.2807 | Soluble |
| 176 | V | A | 0.1262 | Aggregation-prone |
| 177 | H | A | -0.3340 | Soluble |
| 178 | T | A | -0.0102 | Soluble |
| 179 | F | A | 0.0000 | Buried |
| 180 | P | A | -0.4118 | Soluble |
| 181 | A | A | 0.1288 | Aggregation-prone |
| 182 | V | A | 0.4334 | Aggregation-prone |
| 183 | L | A | 0.8968 | Aggregation-prone |
| 184 | Q | A | 0.1927 | Aggregation-prone |
| 185 | S | A | -0.1131 | Soluble |
| 186 | S | A | -0.2555 | Soluble |
| 187 | G | A | -0.0319 | Soluble |
| 188 | L | A | 0.0386 | Aggregation-prone |
| 189 | Y | A | 0.3082 | Aggregation-prone |
| 190 | S | A | 0.0000 | Buried |
| 191 | L | A | 0.0000 | Buried |
| 192 | S | A | 0.0000 | Buried |
| 193 | S | A | 0.0000 | Buried |
| 194 | V | A | 0.0000 | Buried |
| 195 | V | A | 0.0000 | Buried |
| 196 | T | A | -0.1679 | Soluble |
| 197 | V | A | 0.0000 | Buried |
| 198 | P | A | -0.6681 | Soluble |
| 199 | S | A | -0.6290 | Soluble |
| 200 | S | A | -0.6232 | Soluble |
| 201 | S | A | -0.6771 | Soluble |
| 202 | L | A | -0.8881 | Soluble |
| 203 | G | A | -0.9953 | Soluble |
| 204 | T | A | -0.7698 | Soluble |
| 205 | Q | A | -1.3188 | Soluble |
| 206 | T | A | -1.1562 | Soluble |
| 207 | Y | A | 0.0000 | Buried |
| 208 | I | A | -1.2718 | Soluble |
| 209 | C | A | 0.0000 | Buried |
| 210 | N | A | -1.4159 | Soluble |
| 211 | V | A | 0.0000 | Buried |
| 212 | N | A | -1.7505 | Soluble |
| 213 | H | A | 0.0000 | Buried |
| 214 | K | A | -2.7698 | Soluble |
| 215 | P | A | -1.6256 | Soluble |
| 216 | S | A | -1.8215 | Soluble |
| 217 | N | A | -2.5240 | Soluble |
| 218 | T | A | -2.0108 | Soluble |
| 219 | K | A | -2.5990 | Soluble |
| 220 | V | A | -1.6162 | Soluble |
| 221 | D | A | -2.4465 | Soluble |
| 222 | K | A | -2.1147 | Soluble |
| 223 | K | A | -2.4881 | Soluble |
| 224 | V | A | 0.0000 | Buried |
| 225 | E | A | -2.8956 | Soluble |
| 226 | P | A | -1.9584 | Soluble |
| 227 | K | A | -2.5728 | Soluble |
| 228 | S | A | -1.2736 | Soluble |
| 1 | D | B | -2.0198 | Soluble |
| 2 | I | B | -1.4651 | Soluble |
| 3 | Q | B | -1.6790 | Soluble |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -1.3847 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.9427 | Soluble |
| 8 | P | B | -0.7144 | Soluble |
| 9 | S | B | -1.0258 | Soluble |
| 10 | S | B | -1.1065 | Soluble |
| 11 | L | B | -0.7847 | Soluble |
| 12 | S | B | -0.9846 | Soluble |
| 13 | A | B | -1.0681 | Soluble |
| 14 | S | B | -0.9314 | Soluble |
| 15 | V | B | -0.1360 | Soluble |
| 16 | G | B | -0.8617 | Soluble |
| 17 | D | B | -1.7191 | Soluble |
| 18 | R | B | -2.3470 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.5091 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.7849 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.7758 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -2.0908 | Soluble |
| 27 | Q | B | -2.6757 | Soluble |
| 28 | D | B | -2.8540 | Soluble |
| 29 | I | B | 0.0000 | Buried |
| 30 | P | B | -1.3928 | Soluble |
| 31 | R | B | -1.9597 | Soluble |
| 34 | S | B | -0.5681 | Soluble |
| 35 | I | B | 0.5617 | Aggregation-prone |
| 36 | S | B | 0.2266 | Aggregation-prone |
| 37 | G | B | 0.0000 | Buried |
| 38 | Y | B | 0.8564 | Aggregation-prone |
| 39 | V | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | -1.2358 | Soluble |
| 45 | K | B | -1.6756 | Soluble |
| 46 | P | B | -1.4331 | Soluble |
| 47 | G | B | -1.7785 | Soluble |
| 48 | K | B | -2.4793 | Soluble |
| 49 | A | B | -1.5091 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.3147 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 1.1229 | Aggregation-prone |
| 56 | W | B | 1.0677 | Aggregation-prone |
| 57 | G | B | 0.3534 | Aggregation-prone |
| 65 | S | B | 0.5583 | Aggregation-prone |
| 66 | Y | B | 1.5711 | Aggregation-prone |
| 67 | L | B | 1.2236 | Aggregation-prone |
| 68 | Y | B | 0.5219 | Aggregation-prone |
| 69 | S | B | -0.0573 | Soluble |
| 70 | G | B | -0.4580 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | P | B | -0.3378 | Soluble |
| 74 | S | B | -0.3776 | Soluble |
| 75 | R | B | -0.7264 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.0182 | Soluble |
| 78 | G | B | 0.0294 | Aggregation-prone |
| 79 | S | B | -0.4694 | Soluble |
| 80 | G | B | -1.0570 | Soluble |
| 83 | S | B | -1.0852 | Soluble |
| 84 | G | B | -1.6949 | Soluble |
| 85 | T | B | -2.0592 | Soluble |
| 86 | D | B | -1.7742 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.7151 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.6022 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.3406 | Soluble |
| 93 | S | B | -1.2132 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -1.1125 | Soluble |
| 96 | P | B | -1.5656 | Soluble |
| 97 | E | B | -1.7480 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -1.4184 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | 0.0000 | Buried |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | Y | B | 0.4588 | Aggregation-prone |
| 109 | T | B | -0.1211 | Soluble |
| 114 | T | B | -0.1421 | Soluble |
| 115 | P | B | -0.4055 | Soluble |
| 116 | P | B | 0.0000 | Buried |
| 117 | T | B | -0.4042 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.7309 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -2.0247 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -1.7178 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.3719 | Soluble |
| 128 | R | B | -1.0049 | Soluble |
| 129 | T | B | -0.2346 | Soluble |
| 130 | V | B | 0.0853 | Aggregation-prone |
| 131 | A | B | -0.1898 | Soluble |
| 132 | A | B | -0.1908 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.2288 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.5087 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.6760 | Soluble |
| 142 | D | B | -2.9025 | Soluble |
| 143 | E | B | -2.5304 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.1498 | Soluble |
| 146 | K | B | -2.7088 | Soluble |
| 147 | S | B | -1.6891 | Soluble |
| 148 | G | B | -1.2357 | Soluble |
| 149 | T | B | -1.2259 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -1.0292 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.7901 | Soluble |
| 162 | R | B | -3.0583 | Soluble |
| 163 | E | B | -3.2098 | Soluble |
| 164 | A | B | -2.2962 | Soluble |
| 165 | K | B | -2.3423 | Soluble |
| 166 | V | B | -1.0571 | Soluble |
| 167 | Q | B | -0.7166 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.7866 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.8948 | Soluble |
| 172 | N | B | -1.6015 | Soluble |
| 173 | A | B | -0.3628 | Soluble |
| 174 | L | B | 0.5015 | Aggregation-prone |
| 175 | Q | B | -0.4896 | Soluble |
| 176 | S | B | -0.7403 | Soluble |
| 177 | G | B | -1.3450 | Soluble |
| 178 | N | B | -1.7324 | Soluble |
| 179 | S | B | -1.4822 | Soluble |
| 180 | Q | B | -1.4027 | Soluble |
| 181 | E | B | -1.5955 | Soluble |
| 182 | S | B | -0.8765 | Soluble |
| 183 | V | B | -0.7870 | Soluble |
| 184 | T | B | -1.1935 | Soluble |
| 185 | E | B | -2.2866 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.0083 | Soluble |
| 188 | S | B | -2.0854 | Soluble |
| 189 | K | B | -2.5299 | Soluble |
| 190 | D | B | -1.9162 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.6953 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.5680 | Soluble |
| 201 | L | B | -0.8334 | Soluble |
| 202 | S | B | -1.1015 | Soluble |
| 203 | K | B | -2.1496 | Soluble |
| 204 | A | B | -1.8454 | Soluble |
| 205 | D | B | -2.5101 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.0783 | Soluble |
| 208 | K | B | -3.3823 | Soluble |
| 209 | H | B | -2.8630 | Soluble |
| 210 | K | B | -2.9122 | Soluble |
| 211 | V | B | -1.2979 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -1.0105 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.2214 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.7974 | Soluble |
| 220 | G | B | -0.5074 | Soluble |
| 221 | L | B | -0.2771 | Soluble |
| 222 | S | B | -0.4771 | Soluble |
| 223 | S | B | -0.4429 | Soluble |
| 224 | P | B | -0.5588 | Soluble |
| 225 | V | B | -0.0352 | Soluble |
| 226 | T | B | -0.5582 | Soluble |
| 227 | K | B | -0.7486 | Soluble |
| 228 | S | B | -0.6042 | Soluble |
| 229 | F | B | -0.9152 | Soluble |
| 230 | N | B | -1.8415 | Soluble |
| 231 | R | B | -2.3006 | Soluble |
| 232 | G | B | -2.0206 | Soluble |
| 233 | E | B | -2.4580 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7514 | 2.806 | CSV PDB |
| 4.5 | -0.7938 | 2.8009 | CSV PDB |
| 5.0 | -0.8423 | 2.7958 | CSV PDB |
| 5.5 | -0.8873 | 2.7905 | CSV PDB |
| 6.0 | -0.9178 | 2.7853 | CSV PDB |
| 6.5 | -0.9254 | 2.7801 | CSV PDB |
| 7.0 | -0.9106 | 2.775 | CSV PDB |
| 7.5 | -0.881 | 2.7703 | CSV PDB |
| 8.0 | -0.8432 | 2.7665 | CSV PDB |
| 8.5 | -0.7989 | 2.7639 | CSV PDB |
| 9.0 | -0.7479 | 2.7622 | CSV PDB |