Calculation Parameters
| Chain Sequence(s) |
QVQLVESGGGLVQPGGSLRLSCAASGFTFSYYDIQWVRQAPGKGLEWVSSISPSGQSTYYRREVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARRTGREEGGWIFDYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYTCNVDHKPSNTKVDKRVESKEIVLTQSPATLSVSPGERATLSCRASRSVRRELAWYQQKPGQAPELLIYGASTRETGIPARFSGSGSGTDFTLTINSLEAEDAATYYCQQYRDPPGTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | C (Heavy), D (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | C | -1.4627 | Soluble |
| 2 | V | C | -1.1023 | Soluble |
| 3 | Q | C | -1.3484 | Soluble |
| 4 | L | C | 0.0000 | Buried |
| 5 | V | C | 0.1141 | Aggregation-prone |
| 6 | E | C | 0.0000 | Buried |
| 7 | S | C | -0.5015 | Soluble |
| 8 | G | C | -0.8703 | Soluble |
| 9 | G | C | -0.5775 | Soluble |
| 11 | G | C | -0.4449 | Soluble |
| 12 | L | C | -0.1080 | Soluble |
| 13 | V | C | 0.0000 | Buried |
| 14 | Q | C | -1.7532 | Soluble |
| 15 | P | C | -1.5432 | Soluble |
| 16 | G | C | -1.4989 | Soluble |
| 17 | G | C | -1.1572 | Soluble |
| 18 | S | C | -1.1865 | Soluble |
| 19 | L | C | 0.0000 | Buried |
| 20 | R | C | -1.7460 | Soluble |
| 21 | L | C | 0.0000 | Buried |
| 22 | S | C | -0.1081 | Soluble |
| 23 | C | C | 0.0000 | Buried |
| 24 | A | C | -0.2671 | Soluble |
| 25 | A | C | 0.0000 | Buried |
| 26 | S | C | -1.0296 | Soluble |
| 27 | G | C | -1.0482 | Soluble |
| 28 | F | C | -0.3347 | Soluble |
| 29 | T | C | -0.0795 | Soluble |
| 30 | F | C | 0.0000 | Buried |
| 35 | S | C | 0.1019 | Aggregation-prone |
| 36 | Y | C | 1.2261 | Aggregation-prone |
| 37 | Y | C | 0.6770 | Aggregation-prone |
| 38 | D | C | 0.0000 | Buried |
| 39 | I | C | 0.0000 | Buried |
| 40 | Q | C | 0.0000 | Buried |
| 41 | W | C | 0.0000 | Buried |
| 42 | V | C | 0.0000 | Buried |
| 43 | R | C | 0.0000 | Buried |
| 44 | Q | C | -0.6833 | Soluble |
| 45 | A | C | -1.1051 | Soluble |
| 46 | P | C | -0.9021 | Soluble |
| 47 | G | C | -1.4514 | Soluble |
| 48 | K | C | -2.2296 | Soluble |
| 49 | G | C | -1.3946 | Soluble |
| 50 | L | C | 0.0000 | Buried |
| 51 | E | C | -0.7858 | Soluble |
| 52 | W | C | 0.0000 | Buried |
| 53 | V | C | 0.0000 | Buried |
| 54 | S | C | 0.0000 | Buried |
| 55 | S | C | 0.0000 | Buried |
| 56 | I | C | 0.0000 | Buried |
| 57 | S | C | -0.4275 | Soluble |
| 58 | P | C | -0.9363 | Soluble |
| 59 | S | C | -0.6019 | Soluble |
| 62 | G | C | -1.0313 | Soluble |
| 63 | Q | C | -1.5239 | Soluble |
| 64 | S | C | -0.6274 | Soluble |
| 65 | T | C | 0.1209 | Aggregation-prone |
| 66 | Y | C | 0.3969 | Aggregation-prone |
| 67 | Y | C | -0.8714 | Soluble |
| 68 | R | C | -2.0594 | Soluble |
| 69 | R | C | -3.1991 | Soluble |
| 70 | E | C | -3.1591 | Soluble |
| 71 | V | C | 0.0000 | Buried |
| 72 | K | C | -2.9117 | Soluble |
| 74 | G | C | -1.9485 | Soluble |
| 75 | R | C | -1.6537 | Soluble |
| 76 | F | C | 0.0000 | Buried |
| 77 | T | C | -0.5204 | Soluble |
| 78 | I | C | 0.1744 | Aggregation-prone |
| 79 | S | C | -0.3484 | Soluble |
| 80 | R | C | -1.5980 | Soluble |
| 81 | D | C | -2.6094 | Soluble |
| 82 | N | C | -2.8132 | Soluble |
| 83 | S | C | -2.2044 | Soluble |
| 84 | K | C | -2.8703 | Soluble |
| 85 | N | C | -2.3827 | Soluble |
| 86 | T | C | 0.0000 | Buried |
| 87 | L | C | 0.0000 | Buried |
| 88 | Y | C | -0.0022 | Soluble |
| 89 | L | C | 0.0000 | Buried |
| 90 | Q | C | -1.0788 | Soluble |
| 91 | M | C | 0.0000 | Buried |
| 92 | N | C | -1.4389 | Soluble |
| 93 | S | C | -1.2231 | Soluble |
| 94 | L | C | 0.0000 | Buried |
| 95 | R | C | -2.3447 | Soluble |
| 96 | A | C | -1.7908 | Soluble |
| 97 | E | C | -2.2143 | Soluble |
| 98 | D | C | 0.0000 | Buried |
| 99 | T | C | -0.7043 | Soluble |
| 100 | A | C | 0.0000 | Buried |
| 101 | V | C | 0.2091 | Aggregation-prone |
| 102 | Y | C | 0.0000 | Buried |
| 103 | Y | C | 0.0000 | Buried |
| 104 | C | C | 0.0000 | Buried |
| 105 | A | C | 0.0000 | Buried |
| 106 | R | C | -0.0599 | Soluble |
| 107 | R | C | -0.2447 | Soluble |
| 108 | T | C | -0.9118 | Soluble |
| 109 | G | C | -2.1304 | Soluble |
| 110 | R | C | -3.3319 | Soluble |
| 111 | E | C | -3.6529 | Soluble |
| 111A | E | C | -3.2872 | Soluble |
| 112A | G | C | -2.2110 | Soluble |
| 112 | G | C | -1.5886 | Soluble |
| 113 | W | C | -0.5353 | Soluble |
| 114 | I | C | 0.0000 | Buried |
| 115 | F | C | 0.0000 | Buried |
| 116 | D | C | -0.7465 | Soluble |
| 117 | Y | C | -0.4996 | Soluble |
| 118 | W | C | 0.0000 | Buried |
| 119 | G | C | 0.0000 | Buried |
| 120 | Q | C | -1.4151 | Soluble |
| 121 | G | C | 0.0000 | Buried |
| 122 | T | C | -0.0363 | Soluble |
| 123 | L | C | 0.4112 | Aggregation-prone |
| 124 | V | C | 0.0000 | Buried |
| 125 | T | C | 0.0000 | Buried |
| 126 | V | C | 0.0000 | Buried |
| 127 | S | C | -0.7206 | Soluble |
| 128 | S | C | -0.6486 | Soluble |
| 129 | A | C | -0.4924 | Soluble |
| 130 | S | C | -0.6966 | Soluble |
| 131 | T | C | -0.7260 | Soluble |
| 132 | K | C | -1.5216 | Soluble |
| 133 | G | C | -1.5736 | Soluble |
| 134 | P | C | -0.6649 | Soluble |
| 135 | S | C | -0.5956 | Soluble |
| 136 | V | C | 0.0000 | Buried |
| 137 | F | C | -0.5680 | Soluble |
| 138 | P | C | -0.8983 | Soluble |
| 139 | L | C | 0.0000 | Buried |
| 140 | A | C | -0.4918 | Soluble |
| 141 | P | C | -0.4209 | Soluble |
| 142 | C | C | -0.3504 | Soluble |
| 143 | S | C | -1.1176 | Soluble |
| 144 | R | C | -2.0003 | Soluble |
| 145 | S | C | -1.5425 | Soluble |
| 146 | T | C | -1.3889 | Soluble |
| 147 | S | C | -1.2261 | Soluble |
| 148 | E | C | -2.1569 | Soluble |
| 149 | S | C | -1.2780 | Soluble |
| 150 | T | C | -0.8265 | Soluble |
| 151 | A | C | 0.0000 | Buried |
| 152 | A | C | 0.0000 | Buried |
| 153 | L | C | 0.0000 | Buried |
| 154 | G | C | 0.0000 | Buried |
| 155 | C | C | 0.0000 | Buried |
| 156 | L | C | 0.0000 | Buried |
| 157 | V | C | 0.0000 | Buried |
| 158 | K | C | 0.0000 | Buried |
| 159 | D | C | -0.5723 | Soluble |
| 160 | Y | C | 0.0000 | Buried |
| 161 | F | C | -0.4325 | Soluble |
| 162 | P | C | 0.0000 | Buried |
| 163 | E | C | -0.0919 | Soluble |
| 164 | P | C | -0.3048 | Soluble |
| 165 | V | C | -0.2321 | Soluble |
| 166 | T | C | -0.4197 | Soluble |
| 167 | V | C | -0.3580 | Soluble |
| 168 | S | C | -0.4836 | Soluble |
| 169 | W | C | 0.0000 | Buried |
| 170 | N | C | -0.9710 | Soluble |
| 171 | S | C | -0.7914 | Soluble |
| 172 | G | C | -0.5849 | Soluble |
| 173 | A | C | -0.2545 | Soluble |
| 174 | L | C | -0.0734 | Soluble |
| 175 | T | C | -0.1511 | Soluble |
| 176 | S | C | -0.1539 | Soluble |
| 177 | G | C | -0.1564 | Soluble |
| 178 | V | C | 0.2118 | Aggregation-prone |
| 179 | H | C | -0.0966 | Soluble |
| 180 | T | C | -0.0147 | Soluble |
| 181 | F | C | 0.0000 | Buried |
| 182 | P | C | -0.3183 | Soluble |
| 183 | A | C | 0.1347 | Aggregation-prone |
| 184 | V | C | 0.4439 | Aggregation-prone |
| 185 | L | C | 1.2208 | Aggregation-prone |
| 186 | Q | C | 0.0000 | Buried |
| 187 | S | C | -0.1071 | Soluble |
| 188 | S | C | -0.1786 | Soluble |
| 189 | G | C | 0.1662 | Aggregation-prone |
| 190 | L | C | -0.0194 | Soluble |
| 191 | Y | C | 0.3287 | Aggregation-prone |
| 192 | S | C | 0.0000 | Buried |
| 193 | L | C | 0.0000 | Buried |
| 194 | S | C | 0.0000 | Buried |
| 195 | S | C | 0.0000 | Buried |
| 196 | V | C | 0.0000 | Buried |
| 197 | V | C | 0.0000 | Buried |
| 198 | T | C | -0.1425 | Soluble |
| 199 | V | C | 0.0000 | Buried |
| 200 | P | C | -0.4602 | Soluble |
| 201 | S | C | -0.9790 | Soluble |
| 202 | S | C | -0.5076 | Soluble |
| 203 | S | C | -0.4408 | Soluble |
| 204 | L | C | -0.6808 | Soluble |
| 205 | G | C | -1.2742 | Soluble |
| 206 | T | C | -0.7857 | Soluble |
| 207 | Q | C | -1.2721 | Soluble |
| 208 | T | C | -1.4403 | Soluble |
| 209 | Y | C | 0.0000 | Buried |
| 210 | T | C | -1.4931 | Soluble |
| 211 | C | C | 0.0000 | Buried |
| 212 | N | C | -1.5717 | Soluble |
| 213 | V | C | 0.0000 | Buried |
| 214 | D | C | -2.1006 | Soluble |
| 215 | H | C | 0.0000 | Buried |
| 216 | K | C | -2.7685 | Soluble |
| 217 | P | C | -1.6281 | Soluble |
| 218 | S | C | -1.9129 | Soluble |
| 219 | N | C | -2.5427 | Soluble |
| 220 | T | C | -2.0650 | Soluble |
| 221 | K | C | -2.7083 | Soluble |
| 222 | V | C | -1.5231 | Soluble |
| 223 | D | C | -2.4758 | Soluble |
| 224 | K | C | -1.9403 | Soluble |
| 225 | R | C | -2.2272 | Soluble |
| 226 | V | C | 0.0000 | Buried |
| 227 | E | C | -2.6137 | Soluble |
| 228 | S | C | -2.0449 | Soluble |
| 229 | K | C | -2.3568 | Soluble |
| 1 | E | D | -1.7363 | Soluble |
| 2 | I | D | 0.0000 | Buried |
| 3 | V | D | 0.8558 | Aggregation-prone |
| 4 | L | D | -0.0466 | Soluble |
| 5 | T | D | -0.4104 | Soluble |
| 6 | Q | D | -0.7068 | Soluble |
| 7 | S | D | -0.7108 | Soluble |
| 8 | P | D | -0.4551 | Soluble |
| 9 | A | D | -0.4755 | Soluble |
| 10 | T | D | -0.4314 | Soluble |
| 11 | L | D | -0.3185 | Soluble |
| 12 | S | D | -0.5139 | Soluble |
| 13 | V | D | -1.2478 | Soluble |
| 14 | S | D | -1.8482 | Soluble |
| 15 | P | D | -2.0684 | Soluble |
| 16 | G | D | -2.2648 | Soluble |
| 17 | E | D | -3.4108 | Soluble |
| 18 | R | D | -3.2544 | Soluble |
| 19 | A | D | 0.0000 | Buried |
| 20 | T | D | -0.9067 | Soluble |
| 21 | L | D | 0.0000 | Buried |
| 22 | S | D | -1.0203 | Soluble |
| 23 | C | D | 0.0000 | Buried |
| 24 | R | D | -2.5005 | Soluble |
| 25 | A | D | -1.1559 | Soluble |
| 26 | S | D | -0.7469 | Soluble |
| 27 | R | D | -1.9621 | Soluble |
| 28 | S | D | -2.3871 | Soluble |
| 29 | V | D | 0.0000 | Buried |
| 36 | R | D | -3.5939 | Soluble |
| 37 | R | D | -3.2620 | Soluble |
| 38 | E | D | -2.5152 | Soluble |
| 39 | L | D | 0.0000 | Buried |
| 40 | A | D | 0.0000 | Buried |
| 41 | W | D | 0.0000 | Buried |
| 42 | Y | D | 0.0000 | Buried |
| 43 | Q | D | -1.1556 | Soluble |
| 44 | Q | D | -1.4026 | Soluble |
| 45 | K | D | -2.0248 | Soluble |
| 46 | P | D | -1.5372 | Soluble |
| 47 | G | D | -1.6000 | Soluble |
| 48 | Q | D | -2.1676 | Soluble |
| 49 | A | D | -1.5492 | Soluble |
| 50 | P | D | 0.0000 | Buried |
| 51 | E | D | -2.1334 | Soluble |
| 52 | L | D | 0.0000 | Buried |
| 53 | L | D | 0.0000 | Buried |
| 54 | I | D | 0.0000 | Buried |
| 55 | Y | D | -0.7691 | Soluble |
| 56 | G | D | -1.4714 | Soluble |
| 57 | A | D | 0.0000 | Buried |
| 65 | S | D | -1.0113 | Soluble |
| 66 | T | D | -0.9734 | Soluble |
| 67 | R | D | -2.0531 | Soluble |
| 68 | E | D | -1.5283 | Soluble |
| 69 | T | D | -0.8627 | Soluble |
| 70 | G | D | -0.8395 | Soluble |
| 71 | I | D | -0.8098 | Soluble |
| 72 | P | D | -0.6282 | Soluble |
| 74 | A | D | -0.6424 | Soluble |
| 75 | R | D | -1.1351 | Soluble |
| 76 | F | D | 0.0000 | Buried |
| 77 | S | D | -0.7730 | Soluble |
| 78 | G | D | 0.0000 | Buried |
| 79 | S | D | -0.8076 | Soluble |
| 80 | G | D | -1.7795 | Soluble |
| 83 | S | D | -2.3648 | Soluble |
| 84 | G | D | -2.5174 | Soluble |
| 85 | T | D | -2.5675 | Soluble |
| 86 | D | D | -2.9621 | Soluble |
| 87 | F | D | 0.0000 | Buried |
| 88 | T | D | -0.8628 | Soluble |
| 89 | L | D | 0.0000 | Buried |
| 90 | T | D | -0.8198 | Soluble |
| 91 | I | D | 0.0000 | Buried |
| 92 | N | D | -2.2875 | Soluble |
| 93 | S | D | -2.2275 | Soluble |
| 94 | L | D | 0.0000 | Buried |
| 95 | E | D | -2.3781 | Soluble |
| 96 | A | D | -2.5187 | Soluble |
| 97 | E | D | -2.7659 | Soluble |
| 98 | D | D | 0.0000 | Buried |
| 99 | A | D | 0.0000 | Buried |
| 100 | A | D | 0.0000 | Buried |
| 101 | T | D | -0.7604 | Soluble |
| 102 | Y | D | 0.0000 | Buried |
| 103 | Y | D | 0.0000 | Buried |
| 104 | C | D | 0.0000 | Buried |
| 105 | Q | D | 0.0000 | Buried |
| 106 | Q | D | 0.0000 | Buried |
| 107 | Y | D | 0.0000 | Buried |
| 108 | R | D | -2.9977 | Soluble |
| 109 | D | D | -1.9629 | Soluble |
| 114 | P | D | -1.2548 | Soluble |
| 115 | P | D | -0.7277 | Soluble |
| 116 | G | D | 0.0000 | Buried |
| 117 | T | D | -0.2196 | Soluble |
| 118 | F | D | 0.0000 | Buried |
| 119 | G | D | 0.0000 | Buried |
| 120 | G | D | -1.0192 | Soluble |
| 121 | G | D | 0.0000 | Buried |
| 122 | T | D | 0.0000 | Buried |
| 123 | K | D | -1.1462 | Soluble |
| 124 | V | D | 0.0000 | Buried |
| 125 | E | D | -1.2249 | Soluble |
| 126 | I | D | 0.0000 | Buried |
| 127 | K | D | -1.2074 | Soluble |
| 128 | R | D | -0.7514 | Soluble |
| 129 | T | D | 0.2123 | Aggregation-prone |
| 130 | V | D | 1.2167 | Aggregation-prone |
| 131 | A | D | 0.0000 | Buried |
| 132 | A | D | 0.0611 | Aggregation-prone |
| 133 | P | D | -0.0270 | Soluble |
| 134 | S | D | 0.0257 | Aggregation-prone |
| 135 | V | D | 0.0081 | Aggregation-prone |
| 136 | F | D | 0.0889 | Aggregation-prone |
| 137 | I | D | 0.1210 | Aggregation-prone |
| 138 | F | D | 0.0000 | Buried |
| 139 | P | D | -0.1424 | Soluble |
| 140 | P | D | 0.0000 | Buried |
| 141 | S | D | -1.6513 | Soluble |
| 142 | D | D | -3.0428 | Soluble |
| 143 | E | D | -3.0813 | Soluble |
| 144 | Q | D | 0.0000 | Buried |
| 145 | L | D | 0.0000 | Buried |
| 146 | K | D | -3.0746 | Soluble |
| 147 | S | D | -1.9340 | Soluble |
| 148 | G | D | -1.4457 | Soluble |
| 149 | T | D | -1.0411 | Soluble |
| 150 | A | D | 0.0000 | Buried |
| 151 | S | D | 0.0000 | Buried |
| 152 | V | D | 0.0000 | Buried |
| 153 | V | D | 0.0000 | Buried |
| 154 | C | D | 0.0000 | Buried |
| 155 | L | D | 0.0000 | Buried |
| 156 | L | D | 0.0000 | Buried |
| 157 | N | D | -0.2214 | Soluble |
| 158 | N | D | -0.6567 | Soluble |
| 159 | F | D | 0.0000 | Buried |
| 160 | Y | D | 0.0000 | Buried |
| 161 | P | D | -1.4116 | Soluble |
| 162 | R | D | -2.3882 | Soluble |
| 163 | E | D | -2.9533 | Soluble |
| 164 | A | D | -2.2054 | Soluble |
| 165 | K | D | -2.4143 | Soluble |
| 166 | V | D | -0.9498 | Soluble |
| 167 | Q | D | -0.4131 | Soluble |
| 168 | W | D | 0.0000 | Buried |
| 169 | K | D | -0.6037 | Soluble |
| 170 | V | D | 0.0000 | Buried |
| 171 | D | D | -1.8532 | Soluble |
| 172 | N | D | -1.5116 | Soluble |
| 173 | A | D | -0.5182 | Soluble |
| 174 | L | D | 0.2755 | Aggregation-prone |
| 175 | Q | D | -0.4442 | Soluble |
| 176 | S | D | -0.4551 | Soluble |
| 177 | G | D | -0.7850 | Soluble |
| 178 | N | D | -0.8605 | Soluble |
| 179 | S | D | -1.0678 | Soluble |
| 180 | Q | D | -1.2122 | Soluble |
| 181 | E | D | -1.9229 | Soluble |
| 182 | S | D | 0.0000 | Buried |
| 183 | V | D | -0.6929 | Soluble |
| 184 | T | D | -1.0012 | Soluble |
| 185 | E | D | -2.0176 | Soluble |
| 186 | Q | D | -2.1762 | Soluble |
| 187 | D | D | -2.6734 | Soluble |
| 188 | S | D | -2.6400 | Soluble |
| 189 | K | D | -3.0205 | Soluble |
| 190 | D | D | -2.5221 | Soluble |
| 191 | S | D | 0.0000 | Buried |
| 192 | T | D | 0.0000 | Buried |
| 193 | Y | D | 0.0000 | Buried |
| 194 | S | D | 0.0000 | Buried |
| 195 | L | D | 0.0000 | Buried |
| 196 | S | D | 0.0000 | Buried |
| 197 | S | D | 0.0000 | Buried |
| 198 | T | D | 0.0000 | Buried |
| 199 | L | D | 0.0000 | Buried |
| 200 | T | D | -0.3103 | Soluble |
| 201 | L | D | -0.5544 | Soluble |
| 202 | S | D | -1.0604 | Soluble |
| 203 | K | D | -2.0090 | Soluble |
| 204 | A | D | -1.6523 | Soluble |
| 205 | D | D | -2.3900 | Soluble |
| 206 | Y | D | 0.0000 | Buried |
| 207 | E | D | -2.6443 | Soluble |
| 208 | K | D | -3.0835 | Soluble |
| 209 | H | D | -2.4722 | Soluble |
| 210 | K | D | -2.5495 | Soluble |
| 211 | V | D | -1.5126 | Soluble |
| 212 | Y | D | 0.0000 | Buried |
| 213 | A | D | 0.0000 | Buried |
| 214 | C | D | 0.0000 | Buried |
| 215 | E | D | -0.8158 | Soluble |
| 216 | V | D | 0.0000 | Buried |
| 217 | T | D | -1.1752 | Soluble |
| 218 | H | D | 0.0000 | Buried |
| 219 | Q | D | -1.2721 | Soluble |
| 220 | G | D | -0.2500 | Soluble |
| 221 | L | D | -0.2478 | Soluble |
| 222 | S | D | -0.4989 | Soluble |
| 223 | S | D | -0.4498 | Soluble |
| 224 | P | D | -0.6291 | Soluble |
| 225 | V | D | -0.1678 | Soluble |
| 226 | T | D | -0.6993 | Soluble |
| 227 | K | D | -1.2789 | Soluble |
| 228 | S | D | -0.6889 | Soluble |
| 229 | F | D | -0.7302 | Soluble |
| 230 | N | D | -1.5267 | Soluble |
| 231 | R | D | -1.9466 | Soluble |
| 232 | G | D | -1.8015 | Soluble |
| 233 | E | D | -1.9990 | Soluble |
| 234 | C | D | -0.5483 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.8663 | 1.7233 | CSV PDB |
| 4.5 | -0.9173 | 1.6632 | CSV PDB |
| 5.0 | -0.9786 | 1.5872 | CSV PDB |
| 5.5 | -1.0382 | 1.5056 | CSV PDB |
| 6.0 | -1.0838 | 1.4287 | CSV PDB |
| 6.5 | -1.1058 | 1.3664 | CSV PDB |
| 7.0 | -1.1036 | 1.3236 | CSV PDB |
| 7.5 | -1.0848 | 1.3208 | CSV PDB |
| 8.0 | -1.0569 | 1.4583 | CSV PDB |
| 8.5 | -1.0227 | 1.5983 | CSV PDB |
| 9.0 | -0.9827 | 1.7382 | CSV PDB |