Calculation Parameters
| Chain Sequence(s) |
QVQLQQWGAGLLKPSETLSLTCAVYGGSFSGYYWSWIRQSPEKGLEWIGEINHGGYVTYNPSLESRVTISVDTSKNQFSLKLSSVTAADTAVYYCARDYGPGNYDWYFDLWGRGTLVTVSSASTKGPSVFPLAPSSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKEIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPALTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.3120 | Soluble |
| 2 | V | A | -0.6805 | Soluble |
| 3 | Q | A | -1.5325 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | Q | A | -1.4030 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | W | A | 0.1073 | Aggregation-prone |
| 8 | G | A | 0.1132 | Aggregation-prone |
| 9 | A | A | 0.1962 | Aggregation-prone |
| 11 | G | A | 0.4716 | Aggregation-prone |
| 12 | L | A | 0.4931 | Aggregation-prone |
| 13 | L | A | 0.0000 | Buried |
| 14 | K | A | -1.3131 | Soluble |
| 15 | P | A | -1.0178 | Soluble |
| 16 | S | A | -1.2844 | Soluble |
| 17 | E | A | -1.8730 | Soluble |
| 18 | T | A | -1.2640 | Soluble |
| 19 | L | A | 0.0000 | Buried |
| 20 | S | A | -0.6285 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | T | A | -0.3069 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | 0.0000 | Buried |
| 25 | V | A | 0.0000 | Buried |
| 26 | Y | A | -0.3580 | Soluble |
| 27 | G | A | -0.6094 | Soluble |
| 28 | G | A | -0.5642 | Soluble |
| 29 | S | A | -0.3213 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | S | A | -0.5877 | Soluble |
| 36 | G | A | -0.4863 | Soluble |
| 37 | Y | A | 0.0479 | Aggregation-prone |
| 38 | Y | A | 0.5126 | Aggregation-prone |
| 39 | W | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | I | A | 0.0000 | Buried |
| 43 | R | A | -0.2709 | Soluble |
| 44 | Q | A | -0.6848 | Soluble |
| 45 | S | A | 0.0000 | Buried |
| 46 | P | A | -1.6438 | Soluble |
| 47 | E | A | -2.8317 | Soluble |
| 48 | K | A | -2.9050 | Soluble |
| 49 | G | A | -1.8848 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.8286 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | I | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | E | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | N | A | 0.1601 | Aggregation-prone |
| 58 | H | A | -0.5853 | Soluble |
| 59 | G | A | -0.2963 | Soluble |
| 63 | G | A | 0.2215 | Aggregation-prone |
| 64 | Y | A | 1.4725 | Aggregation-prone |
| 65 | V | A | 1.5069 | Aggregation-prone |
| 66 | T | A | 0.4356 | Aggregation-prone |
| 67 | Y | A | -0.3910 | Soluble |
| 68 | N | A | -0.8843 | Soluble |
| 69 | P | A | -1.3031 | Soluble |
| 70 | S | A | -0.9551 | Soluble |
| 71 | L | A | 0.0000 | Buried |
| 72 | E | A | -2.2085 | Soluble |
| 74 | S | A | -1.4125 | Soluble |
| 75 | R | A | -1.3437 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.6590 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.0761 | Soluble |
| 80 | V | A | -0.4641 | Soluble |
| 81 | D | A | -1.4382 | Soluble |
| 82 | T | A | -1.3272 | Soluble |
| 83 | S | A | -1.4077 | Soluble |
| 84 | K | A | -2.1440 | Soluble |
| 85 | N | A | -1.4839 | Soluble |
| 86 | Q | A | -1.2332 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | S | A | 0.0000 | Buried |
| 89 | L | A | 0.0000 | Buried |
| 90 | K | A | -0.9901 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | S | A | -0.9807 | Soluble |
| 93 | S | A | -1.0927 | Soluble |
| 94 | V | A | 0.0000 | Buried |
| 95 | T | A | -0.4989 | Soluble |
| 96 | A | A | -0.1418 | Soluble |
| 97 | A | A | -0.4172 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | 0.1372 | Aggregation-prone |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.7044 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.1311 | Soluble |
| 107 | D | A | 0.0000 | Buried |
| 108 | Y | A | -0.0311 | Soluble |
| 109 | G | A | -0.5930 | Soluble |
| 110 | P | A | -0.7598 | Soluble |
| 111 | G | A | -1.1955 | Soluble |
| 111A | N | A | -1.5353 | Soluble |
| 112A | Y | A | -0.7016 | Soluble |
| 112 | D | A | -0.5597 | Soluble |
| 113 | W | A | -0.2993 | Soluble |
| 114 | Y | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.6529 | Soluble |
| 117 | L | A | -0.4890 | Soluble |
| 118 | W | A | -1.0153 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | R | A | -2.1881 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.3342 | Aggregation-prone |
| 123 | L | A | 1.5002 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.3390 | Aggregation-prone |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.3475 | Soluble |
| 128 | S | A | -0.5821 | Soluble |
| 129 | A | A | -0.6375 | Soluble |
| 130 | S | A | -0.8141 | Soluble |
| 131 | T | A | -1.1973 | Soluble |
| 132 | K | A | -2.0670 | Soluble |
| 133 | G | A | -1.8488 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.6025 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.0299 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | 0.0000 | Buried |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.6209 | Soluble |
| 143 | S | A | -0.6609 | Soluble |
| 144 | S | A | -0.6703 | Soluble |
| 145 | G | A | -0.8611 | Soluble |
| 146 | G | A | -0.8734 | Soluble |
| 147 | T | A | -0.6017 | Soluble |
| 148 | A | A | 0.0000 | Buried |
| 149 | A | A | 0.0000 | Buried |
| 150 | L | A | 0.0000 | Buried |
| 151 | G | A | 0.0000 | Buried |
| 152 | C | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | V | A | 0.0000 | Buried |
| 155 | K | A | 0.0000 | Buried |
| 156 | D | A | -0.9421 | Soluble |
| 157 | Y | A | 0.0000 | Buried |
| 158 | F | A | 0.0000 | Buried |
| 159 | P | A | -1.0213 | Soluble |
| 160 | E | A | -1.2130 | Soluble |
| 161 | P | A | -1.0900 | Soluble |
| 162 | V | A | -0.8129 | Soluble |
| 163 | T | A | -0.5738 | Soluble |
| 164 | V | A | -0.3515 | Soluble |
| 165 | S | A | -0.3531 | Soluble |
| 166 | W | A | 0.0000 | Buried |
| 167 | N | A | -0.7444 | Soluble |
| 168 | S | A | -0.6819 | Soluble |
| 169 | G | A | -0.5540 | Soluble |
| 170 | A | A | -0.2507 | Soluble |
| 171 | L | A | -0.0035 | Soluble |
| 172 | T | A | -0.0974 | Soluble |
| 173 | S | A | -0.1179 | Soluble |
| 174 | G | A | 0.0098 | Aggregation-prone |
| 175 | V | A | 0.2627 | Aggregation-prone |
| 176 | H | A | -0.0918 | Soluble |
| 177 | T | A | 0.0132 | Aggregation-prone |
| 178 | F | A | 0.0000 | Buried |
| 179 | P | A | -0.3440 | Soluble |
| 180 | A | A | 0.1361 | Aggregation-prone |
| 181 | V | A | 0.6895 | Aggregation-prone |
| 182 | L | A | 1.2710 | Aggregation-prone |
| 183 | Q | A | 0.3415 | Aggregation-prone |
| 184 | S | A | -0.0275 | Soluble |
| 185 | S | A | -0.2142 | Soluble |
| 186 | G | A | 0.0430 | Aggregation-prone |
| 187 | L | A | -0.2002 | Soluble |
| 188 | Y | A | 0.1639 | Aggregation-prone |
| 189 | S | A | 0.0000 | Buried |
| 190 | L | A | 0.0000 | Buried |
| 191 | S | A | 0.0000 | Buried |
| 192 | S | A | 0.0000 | Buried |
| 193 | V | A | 0.0000 | Buried |
| 194 | V | A | 0.0000 | Buried |
| 195 | T | A | -0.0444 | Soluble |
| 196 | V | A | 0.0000 | Buried |
| 197 | P | A | -0.5456 | Soluble |
| 198 | S | A | -0.5692 | Soluble |
| 199 | S | A | -0.5605 | Soluble |
| 200 | S | A | -0.5715 | Soluble |
| 201 | L | A | -0.8139 | Soluble |
| 202 | G | A | -1.0690 | Soluble |
| 203 | T | A | -0.7457 | Soluble |
| 204 | Q | A | -1.2937 | Soluble |
| 205 | T | A | -1.1602 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | I | A | -1.3290 | Soluble |
| 208 | C | A | 0.0000 | Buried |
| 209 | N | A | -1.4707 | Soluble |
| 210 | V | A | 0.0000 | Buried |
| 211 | N | A | -1.7805 | Soluble |
| 212 | H | A | 0.0000 | Buried |
| 213 | K | A | -2.8072 | Soluble |
| 214 | P | A | -1.8974 | Soluble |
| 215 | S | A | -2.0490 | Soluble |
| 216 | N | A | -2.4676 | Soluble |
| 217 | T | A | -2.2828 | Soluble |
| 218 | K | A | -2.6231 | Soluble |
| 219 | V | A | -1.5986 | Soluble |
| 220 | D | A | -2.5402 | Soluble |
| 221 | K | A | -2.0364 | Soluble |
| 222 | K | A | -2.6245 | Soluble |
| 223 | V | A | 0.0000 | Buried |
| 224 | E | A | -2.8823 | Soluble |
| 225 | P | A | -1.9829 | Soluble |
| 226 | K | A | -2.4972 | Soluble |
| 1 | E | B | -1.5256 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.5469 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.6462 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.7265 | Soluble |
| 8 | P | B | -0.3633 | Soluble |
| 9 | A | B | -0.3869 | Soluble |
| 10 | T | B | -0.3913 | Soluble |
| 11 | L | B | -0.1951 | Soluble |
| 12 | S | B | -0.5713 | Soluble |
| 13 | L | B | -0.9687 | Soluble |
| 14 | S | B | -1.3881 | Soluble |
| 15 | P | B | -1.7369 | Soluble |
| 16 | G | B | -1.8896 | Soluble |
| 17 | E | B | -2.5282 | Soluble |
| 18 | R | B | -2.7388 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.6792 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.8763 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.2756 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.8748 | Soluble |
| 27 | Q | B | -1.1699 | Soluble |
| 28 | S | B | -1.0222 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 36 | S | B | -0.5972 | Soluble |
| 37 | S | B | -0.4570 | Soluble |
| 38 | Y | B | 0.0958 | Aggregation-prone |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.4160 | Soluble |
| 46 | P | B | -1.2544 | Soluble |
| 47 | G | B | -1.5299 | Soluble |
| 48 | Q | B | -2.2286 | Soluble |
| 49 | A | B | -1.5270 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.5558 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | -0.7146 | Soluble |
| 56 | D | B | -0.8231 | Soluble |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -1.2363 | Soluble |
| 66 | N | B | -1.8161 | Soluble |
| 67 | R | B | -1.6212 | Soluble |
| 68 | A | B | -1.0774 | Soluble |
| 69 | T | B | -0.6545 | Soluble |
| 70 | G | B | -0.5448 | Soluble |
| 71 | I | B | -0.4659 | Soluble |
| 72 | P | B | -0.3496 | Soluble |
| 74 | A | B | -0.3082 | Soluble |
| 75 | R | B | -0.7033 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.6817 | Soluble |
| 78 | G | B | -0.7927 | Soluble |
| 79 | S | B | -0.8287 | Soluble |
| 80 | G | B | -0.9389 | Soluble |
| 83 | S | B | -0.8951 | Soluble |
| 84 | G | B | -1.0767 | Soluble |
| 85 | T | B | -1.6372 | Soluble |
| 86 | D | B | -2.2134 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.7720 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.5578 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.2308 | Soluble |
| 93 | S | B | -1.7811 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -2.0799 | Soluble |
| 96 | P | B | -1.5455 | Soluble |
| 97 | E | B | -2.2203 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -0.6790 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.3374 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | R | B | -0.3056 | Soluble |
| 108 | S | B | -0.6584 | Soluble |
| 109 | N | B | -0.8770 | Soluble |
| 110 | W | B | 0.2081 | Aggregation-prone |
| 113 | P | B | -0.2809 | Soluble |
| 114 | P | B | -0.8591 | Soluble |
| 115 | A | B | -0.6778 | Soluble |
| 116 | L | B | 0.0000 | Buried |
| 117 | T | B | -0.1275 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.7261 | Soluble |
| 121 | G | B | -0.5437 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -0.9310 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | 0.0000 | Buried |
| 126 | I | B | -0.5622 | Soluble |
| 127 | K | B | -1.1607 | Soluble |
| 128 | R | B | -0.8608 | Soluble |
| 129 | T | B | -0.1161 | Soluble |
| 130 | V | B | 0.3676 | Aggregation-prone |
| 131 | A | B | -0.0149 | Soluble |
| 132 | A | B | -0.0993 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1664 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | -0.0363 | Soluble |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.4707 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | 0.0000 | Buried |
| 142 | D | B | -2.5418 | Soluble |
| 143 | E | B | -2.3513 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.0917 | Soluble |
| 146 | K | B | -2.6267 | Soluble |
| 147 | S | B | -1.6738 | Soluble |
| 148 | G | B | -1.2449 | Soluble |
| 149 | T | B | -0.9919 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.8592 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.7334 | Soluble |
| 162 | R | B | -2.8812 | Soluble |
| 163 | E | B | -3.2144 | Soluble |
| 164 | A | B | -2.3593 | Soluble |
| 165 | K | B | -2.3234 | Soluble |
| 166 | V | B | -1.3933 | Soluble |
| 167 | Q | B | -0.7636 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.6752 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.9085 | Soluble |
| 172 | N | B | -1.3782 | Soluble |
| 173 | A | B | -0.3330 | Soluble |
| 174 | L | B | 0.5815 | Aggregation-prone |
| 175 | Q | B | -0.3743 | Soluble |
| 176 | S | B | -0.6495 | Soluble |
| 177 | G | B | -1.2392 | Soluble |
| 178 | N | B | -1.5095 | Soluble |
| 179 | S | B | -1.3966 | Soluble |
| 180 | Q | B | -1.3682 | Soluble |
| 181 | E | B | -1.8839 | Soluble |
| 182 | S | B | -1.0260 | Soluble |
| 183 | V | B | -0.9509 | Soluble |
| 184 | T | B | -1.2536 | Soluble |
| 185 | E | B | -2.2755 | Soluble |
| 186 | Q | B | -1.8987 | Soluble |
| 187 | D | B | -1.9512 | Soluble |
| 188 | S | B | -1.6990 | Soluble |
| 189 | K | B | -2.2642 | Soluble |
| 190 | D | B | -1.7023 | Soluble |
| 191 | S | B | -1.6718 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7420 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.6283 | Soluble |
| 201 | L | B | -0.8623 | Soluble |
| 202 | S | B | -1.1245 | Soluble |
| 203 | K | B | -2.1848 | Soluble |
| 204 | A | B | -1.9546 | Soluble |
| 205 | D | B | -2.6728 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.6039 | Soluble |
| 208 | K | B | -3.7092 | Soluble |
| 209 | H | B | -3.1343 | Soluble |
| 210 | K | B | -3.2109 | Soluble |
| 211 | V | B | -1.4482 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | -0.7125 | Soluble |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -1.1477 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.3182 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.7331 | Soluble |
| 220 | G | B | -0.4145 | Soluble |
| 221 | L | B | -0.2022 | Soluble |
| 222 | S | B | -0.4420 | Soluble |
| 223 | S | B | -0.4223 | Soluble |
| 224 | P | B | -0.6395 | Soluble |
| 225 | V | B | -0.1091 | Soluble |
| 226 | T | B | -0.5629 | Soluble |
| 227 | K | B | -0.6421 | Soluble |
| 228 | S | B | -0.6052 | Soluble |
| 229 | F | B | -1.0389 | Soluble |
| 230 | N | B | -2.1474 | Soluble |
| 231 | R | B | -2.7935 | Soluble |
| 232 | G | B | -2.4021 | Soluble |
| 233 | E | B | -2.8188 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6173 | 3.8379 | CSV PDB |
| 4.5 | -0.6576 | 3.8145 | CSV PDB |
| 5.0 | -0.7071 | 3.7767 | CSV PDB |
| 5.5 | -0.7557 | 3.73 | CSV PDB |
| 6.0 | -0.7916 | 3.6821 | CSV PDB |
| 6.5 | -0.8052 | 3.6404 | CSV PDB |
| 7.0 | -0.7953 | 3.6119 | CSV PDB |
| 7.5 | -0.7686 | 3.5975 | CSV PDB |
| 8.0 | -0.7326 | 3.5919 | CSV PDB |
| 8.5 | -0.6907 | 3.59 | CSV PDB |
| 9.0 | -0.6436 | 3.5893 | CSV PDB |