Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGYTFTNYGMNWVRQAPGKGLEWVGWINTYTGEPTYAADFKRRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCAKYPHYYGSSHWYFDVWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPDIQMTQSPSSLSASVGDRVTITCSASQDISNYLNWYQQKPGKAPKVLIYFTSSLHSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYSTVPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | B | -2.0436 | Soluble |
| 2 | V | B | -1.2200 | Soluble |
| 3 | Q | B | -1.2343 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | 0.9048 | Aggregation-prone |
| 6 | E | B | 0.0000 | Buried |
| 7 | S | B | -0.4821 | Soluble |
| 8 | G | B | -0.9716 | Soluble |
| 9 | G | B | -0.5542 | Soluble |
| 11 | G | B | -0.2974 | Soluble |
| 12 | L | B | -0.1405 | Soluble |
| 13 | V | B | 0.0000 | Buried |
| 14 | Q | B | -1.7217 | Soluble |
| 15 | P | B | -1.8547 | Soluble |
| 16 | G | B | -1.5159 | Soluble |
| 17 | G | B | -1.2152 | Soluble |
| 18 | S | B | -1.3597 | Soluble |
| 19 | L | B | -1.2536 | Soluble |
| 20 | R | B | -2.2061 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.4194 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | A | B | -0.0667 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.9521 | Soluble |
| 27 | G | B | -1.1885 | Soluble |
| 28 | Y | B | -0.7772 | Soluble |
| 29 | T | B | -0.5542 | Soluble |
| 30 | F | B | 0.0000 | Buried |
| 35 | T | B | -0.3144 | Soluble |
| 36 | N | B | -1.1903 | Soluble |
| 37 | Y | B | 0.0000 | Buried |
| 38 | G | B | 0.0000 | Buried |
| 39 | M | B | 0.0000 | Buried |
| 40 | N | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | -0.6213 | Soluble |
| 44 | Q | B | -0.9193 | Soluble |
| 45 | A | B | -1.2333 | Soluble |
| 46 | P | B | -0.9882 | Soluble |
| 47 | G | B | -1.4916 | Soluble |
| 48 | K | B | -2.3697 | Soluble |
| 49 | G | B | -1.6293 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -1.2794 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | V | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | W | B | -0.1972 | Soluble |
| 56 | I | B | 0.0000 | Buried |
| 57 | N | B | -0.8349 | Soluble |
| 58 | T | B | 0.0000 | Buried |
| 59 | Y | B | 0.5751 | Aggregation-prone |
| 62 | T | B | -0.2277 | Soluble |
| 63 | G | B | -0.8564 | Soluble |
| 64 | E | B | -1.9045 | Soluble |
| 65 | P | B | -1.2666 | Soluble |
| 66 | T | B | -0.4951 | Soluble |
| 67 | Y | B | -0.6513 | Soluble |
| 68 | A | B | 0.0000 | Buried |
| 69 | A | B | -1.2920 | Soluble |
| 70 | D | B | -2.4817 | Soluble |
| 71 | F | B | 0.0000 | Buried |
| 72 | K | B | -2.7755 | Soluble |
| 74 | R | B | -3.0532 | Soluble |
| 75 | R | B | -2.1090 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | T | B | -1.1320 | Soluble |
| 78 | F | B | 0.0000 | Buried |
| 79 | S | B | -0.6830 | Soluble |
| 80 | L | B | -0.2693 | Soluble |
| 81 | D | B | -1.0947 | Soluble |
| 82 | T | B | -0.7686 | Soluble |
| 83 | S | B | -1.2186 | Soluble |
| 84 | K | B | -1.9999 | Soluble |
| 85 | S | B | -1.1315 | Soluble |
| 86 | T | B | 0.0000 | Buried |
| 87 | A | B | 0.0000 | Buried |
| 88 | Y | B | 0.0000 | Buried |
| 89 | L | B | 0.0000 | Buried |
| 90 | Q | B | -1.3568 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | N | B | -1.7435 | Soluble |
| 93 | S | B | -1.5214 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -2.4790 | Soluble |
| 96 | A | B | -1.8029 | Soluble |
| 97 | E | B | -2.2687 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.7805 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.1255 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | K | B | 0.0000 | Buried |
| 107 | Y | B | 0.0000 | Buried |
| 108 | P | B | 0.0000 | Buried |
| 109 | H | B | -0.4303 | Soluble |
| 110 | Y | B | 0.9311 | Aggregation-prone |
| 111 | Y | B | 0.5556 | Aggregation-prone |
| 111A | G | B | 0.1564 | Aggregation-prone |
| 112B | S | B | -0.0913 | Soluble |
| 112A | S | B | 0.1541 | Aggregation-prone |
| 112 | H | B | 0.2265 | Aggregation-prone |
| 113 | W | B | 0.4692 | Aggregation-prone |
| 114 | Y | B | 0.0000 | Buried |
| 115 | F | B | 0.0000 | Buried |
| 116 | D | B | -0.8164 | Soluble |
| 117 | V | B | -0.6316 | Soluble |
| 118 | W | B | -0.5820 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.3209 | Soluble |
| 121 | G | B | -0.6300 | Soluble |
| 122 | T | B | -0.0928 | Soluble |
| 123 | L | B | 0.1676 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | -0.4935 | Soluble |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -0.8495 | Soluble |
| 128 | S | B | -0.7891 | Soluble |
| 129 | A | B | -0.4826 | Soluble |
| 130 | S | B | -0.6108 | Soluble |
| 131 | T | B | -0.6633 | Soluble |
| 132 | K | B | -1.1692 | Soluble |
| 133 | G | B | -1.4185 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.4841 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.1929 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -0.9265 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -0.8169 | Soluble |
| 143 | S | B | -0.7714 | Soluble |
| 144 | K | B | -1.1188 | Soluble |
| 145 | S | B | 0.0000 | Buried |
| 146 | T | B | -0.7175 | Soluble |
| 147 | S | B | -0.8134 | Soluble |
| 148 | G | B | -0.8579 | Soluble |
| 149 | G | B | -0.9138 | Soluble |
| 150 | T | B | -0.6101 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.4024 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.3625 | Soluble |
| 164 | P | B | -0.5976 | Soluble |
| 165 | V | B | -0.5628 | Soluble |
| 166 | T | B | -0.4564 | Soluble |
| 167 | V | B | -0.3527 | Soluble |
| 168 | S | B | -0.4211 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.8116 | Soluble |
| 171 | S | B | -0.7308 | Soluble |
| 172 | G | B | -0.6284 | Soluble |
| 173 | A | B | -0.2784 | Soluble |
| 174 | L | B | 0.0025 | Aggregation-prone |
| 175 | T | B | -0.1681 | Soluble |
| 176 | S | B | -0.1955 | Soluble |
| 177 | G | B | -0.1058 | Soluble |
| 178 | V | B | 0.2185 | Aggregation-prone |
| 179 | H | B | -0.3352 | Soluble |
| 180 | T | B | -0.1430 | Soluble |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.3988 | Soluble |
| 183 | A | B | 0.2044 | Aggregation-prone |
| 184 | V | B | 0.4799 | Aggregation-prone |
| 185 | L | B | 1.0692 | Aggregation-prone |
| 186 | Q | B | 0.1777 | Aggregation-prone |
| 187 | S | B | -0.2031 | Soluble |
| 188 | S | B | -0.2337 | Soluble |
| 189 | G | B | 0.0201 | Aggregation-prone |
| 190 | L | B | 0.1083 | Aggregation-prone |
| 191 | Y | B | 0.4405 | Aggregation-prone |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1028 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.6620 | Soluble |
| 201 | S | B | -0.5793 | Soluble |
| 202 | S | B | -0.6093 | Soluble |
| 203 | S | B | -0.7121 | Soluble |
| 204 | L | B | -0.9236 | Soluble |
| 205 | G | B | -1.1294 | Soluble |
| 206 | T | B | -0.8666 | Soluble |
| 207 | Q | B | -1.6102 | Soluble |
| 208 | T | B | -1.2371 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -1.1653 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.4776 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -1.8534 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.6975 | Soluble |
| 217 | P | B | -1.5580 | Soluble |
| 218 | S | B | -1.8383 | Soluble |
| 219 | N | B | -2.4788 | Soluble |
| 220 | T | B | -2.0449 | Soluble |
| 221 | K | B | -2.6974 | Soluble |
| 222 | V | B | -1.7398 | Soluble |
| 223 | D | B | -2.5501 | Soluble |
| 224 | K | B | -2.1782 | Soluble |
| 225 | K | B | -2.2685 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.4647 | Soluble |
| 228 | P | B | -1.2031 | Soluble |
| 1 | D | A | -2.0771 | Soluble |
| 2 | I | A | 0.0000 | Buried |
| 3 | Q | A | -2.0232 | Soluble |
| 4 | M | A | 0.0000 | Buried |
| 5 | T | A | -0.8890 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.4921 | Soluble |
| 8 | P | A | -0.6243 | Soluble |
| 9 | S | A | -0.9827 | Soluble |
| 10 | S | A | -1.0624 | Soluble |
| 11 | L | A | -0.7472 | Soluble |
| 12 | S | A | -1.1198 | Soluble |
| 13 | A | A | -1.0854 | Soluble |
| 14 | S | A | -1.0020 | Soluble |
| 15 | V | A | -0.1338 | Soluble |
| 16 | G | A | -0.7531 | Soluble |
| 17 | D | A | -1.8311 | Soluble |
| 18 | R | A | -2.2592 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | T | A | -0.6261 | Soluble |
| 21 | I | A | 0.0000 | Buried |
| 22 | T | A | -0.6090 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | S | A | -1.4784 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -2.0442 | Soluble |
| 27 | Q | A | -2.8857 | Soluble |
| 28 | D | A | -2.8524 | Soluble |
| 29 | I | A | 0.0000 | Buried |
| 36 | S | A | -1.2724 | Soluble |
| 37 | N | A | -0.7762 | Soluble |
| 38 | Y | A | 0.0309 | Aggregation-prone |
| 39 | L | A | 0.0000 | Buried |
| 40 | N | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | 0.0000 | Buried |
| 45 | K | A | -1.7412 | Soluble |
| 46 | P | A | -1.4891 | Soluble |
| 47 | G | A | -1.6089 | Soluble |
| 48 | K | A | -2.5757 | Soluble |
| 49 | A | A | -1.6627 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | K | A | -2.0296 | Soluble |
| 52 | V | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | 0.3627 | Aggregation-prone |
| 56 | F | A | 0.5721 | Aggregation-prone |
| 57 | T | A | 0.0000 | Buried |
| 65 | S | A | -0.0948 | Soluble |
| 66 | S | A | 0.1022 | Aggregation-prone |
| 67 | L | A | 0.2434 | Aggregation-prone |
| 68 | H | A | -0.4291 | Soluble |
| 69 | S | A | -0.3886 | Soluble |
| 70 | G | A | -0.5212 | Soluble |
| 71 | V | A | -0.3864 | Soluble |
| 72 | P | A | -0.3663 | Soluble |
| 74 | S | A | -0.3990 | Soluble |
| 75 | R | A | -0.7044 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -0.2898 | Soluble |
| 78 | G | A | -0.1988 | Soluble |
| 79 | S | A | -0.7117 | Soluble |
| 80 | G | A | -1.1211 | Soluble |
| 83 | S | A | -1.3663 | Soluble |
| 84 | G | A | -1.8595 | Soluble |
| 85 | T | A | -2.1446 | Soluble |
| 86 | D | A | -2.4841 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.6652 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.5760 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -1.2510 | Soluble |
| 93 | S | A | -1.1264 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | Q | A | -0.8550 | Soluble |
| 96 | P | A | -1.6270 | Soluble |
| 97 | E | A | -1.8457 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | F | A | -1.2666 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | T | A | -1.0074 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | Q | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | Y | A | 0.0000 | Buried |
| 108 | S | A | -0.4725 | Soluble |
| 109 | T | A | 0.0217 | Aggregation-prone |
| 114 | V | A | 0.7469 | Aggregation-prone |
| 115 | P | A | 0.1742 | Aggregation-prone |
| 116 | W | A | 0.0000 | Buried |
| 117 | T | A | -0.6798 | Soluble |
| 118 | F | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.6330 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -1.9751 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | E | A | -1.3648 | Soluble |
| 126 | I | A | 0.0000 | Buried |
| 127 | K | A | -1.8172 | Soluble |
| 128 | R | A | -1.0619 | Soluble |
| 129 | T | A | -0.2219 | Soluble |
| 130 | V | A | 0.3746 | Aggregation-prone |
| 131 | A | A | 0.1309 | Aggregation-prone |
| 132 | A | A | -0.0989 | Soluble |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.1551 | Soluble |
| 135 | V | A | -0.0791 | Soluble |
| 136 | F | A | 0.0000 | Buried |
| 137 | I | A | 0.0000 | Buried |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.7988 | Soluble |
| 140 | P | A | -0.8412 | Soluble |
| 141 | S | A | -1.6730 | Soluble |
| 142 | D | A | -3.0136 | Soluble |
| 143 | E | A | -3.1451 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.2159 | Soluble |
| 146 | K | A | -2.8289 | Soluble |
| 147 | S | A | -1.7927 | Soluble |
| 148 | G | A | -1.2307 | Soluble |
| 149 | T | A | -0.9760 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -1.0077 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.7081 | Soluble |
| 162 | R | A | -2.5791 | Soluble |
| 163 | E | A | -2.8573 | Soluble |
| 164 | A | A | -1.7920 | Soluble |
| 165 | K | A | -1.5140 | Soluble |
| 166 | V | A | -0.8901 | Soluble |
| 167 | Q | A | -0.6027 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.6408 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -1.5777 | Soluble |
| 172 | N | A | -1.4014 | Soluble |
| 173 | A | A | -0.3264 | Soluble |
| 174 | L | A | 0.2719 | Aggregation-prone |
| 175 | Q | A | -0.3535 | Soluble |
| 176 | S | A | -0.5422 | Soluble |
| 177 | G | A | -0.9216 | Soluble |
| 178 | N | A | -0.8862 | Soluble |
| 179 | S | A | -1.1367 | Soluble |
| 180 | Q | A | -1.3131 | Soluble |
| 181 | E | A | -1.9016 | Soluble |
| 182 | S | A | -0.8338 | Soluble |
| 183 | V | A | -0.7580 | Soluble |
| 184 | T | A | -1.0840 | Soluble |
| 185 | E | A | -2.0146 | Soluble |
| 186 | Q | A | 0.0000 | Buried |
| 187 | D | A | -2.3109 | Soluble |
| 188 | S | A | -2.3263 | Soluble |
| 189 | K | A | -2.7659 | Soluble |
| 190 | D | A | -2.2323 | Soluble |
| 191 | S | A | 0.0000 | Buried |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.7038 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.4124 | Soluble |
| 201 | L | A | -0.6513 | Soluble |
| 202 | S | A | -1.1499 | Soluble |
| 203 | K | A | -1.9119 | Soluble |
| 204 | A | A | -1.7516 | Soluble |
| 205 | D | A | -2.4925 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.3554 | Soluble |
| 208 | K | A | -3.5604 | Soluble |
| 209 | H | A | -2.9709 | Soluble |
| 210 | K | A | -3.1595 | Soluble |
| 211 | V | A | -1.4664 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.4597 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -0.9077 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.6040 | Soluble |
| 220 | G | A | -0.3873 | Soluble |
| 221 | L | A | -0.2168 | Soluble |
| 222 | S | A | -0.4118 | Soluble |
| 223 | S | A | -0.4263 | Soluble |
| 224 | P | A | -0.3763 | Soluble |
| 225 | V | A | 0.1478 | Aggregation-prone |
| 226 | T | A | -0.2210 | Soluble |
| 227 | K | A | -0.4892 | Soluble |
| 228 | S | A | -0.6506 | Soluble |
| 229 | F | A | 0.0000 | Buried |
| 230 | N | A | -2.1911 | Soluble |
| 231 | R | A | -2.4375 | Soluble |
| 232 | G | A | -1.5179 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7068 | 1.7742 | CSV PDB |
| 4.5 | -0.75 | 1.7136 | CSV PDB |
| 5.0 | -0.7998 | 1.6266 | CSV PDB |
| 5.5 | -0.8465 | 1.5289 | CSV PDB |
| 6.0 | -0.8794 | 1.4358 | CSV PDB |
| 6.5 | -0.8905 | 1.362 | CSV PDB |
| 7.0 | -0.88 | 1.3171 | CSV PDB |
| 7.5 | -0.8558 | 1.2969 | CSV PDB |
| 8.0 | -0.824 | 1.3201 | CSV PDB |
| 8.5 | -0.7864 | 1.4799 | CSV PDB |
| 9.0 | -0.7423 | 1.6396 | CSV PDB |