Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFTFTDYTMDWVRQAPGKGLEWVADVNPNSGGSIYNQRFKGRFTLSVDRSKNTLYLQMNSLRAEDTAVYYCARNLGPSFYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDIQMTQSPSSLSASVGDRVTITCKASQDVSIGVAWYQQKPGKAPKLLIYSASYRYTGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYYIYPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | F (Heavy), E (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | F | -2.2661 | Soluble |
| 2 | V | F | 0.0000 | Buried |
| 3 | Q | F | -1.4696 | Soluble |
| 4 | L | F | 0.0000 | Buried |
| 5 | V | F | 1.0003 | Aggregation-prone |
| 6 | E | F | 0.0000 | Buried |
| 7 | S | F | -0.2058 | Soluble |
| 8 | G | F | -0.7071 | Soluble |
| 9 | G | F | -0.0479 | Soluble |
| 11 | G | F | 0.2702 | Aggregation-prone |
| 12 | L | F | 0.8195 | Aggregation-prone |
| 13 | V | F | -0.3739 | Soluble |
| 14 | Q | F | -1.5443 | Soluble |
| 15 | P | F | -1.6978 | Soluble |
| 16 | G | F | -1.6476 | Soluble |
| 17 | G | F | -1.2185 | Soluble |
| 18 | S | F | -1.4216 | Soluble |
| 19 | L | F | -1.2325 | Soluble |
| 20 | R | F | -2.3986 | Soluble |
| 21 | L | F | 0.0000 | Buried |
| 22 | S | F | -0.4303 | Soluble |
| 23 | C | F | 0.0000 | Buried |
| 24 | A | F | -0.2517 | Soluble |
| 25 | A | F | 0.0000 | Buried |
| 26 | S | F | -1.1258 | Soluble |
| 27 | G | F | -1.3954 | Soluble |
| 28 | F | F | -0.7906 | Soluble |
| 29 | T | F | -0.6026 | Soluble |
| 30 | F | F | 0.0000 | Buried |
| 35 | T | F | -1.5151 | Soluble |
| 36 | D | F | -1.8725 | Soluble |
| 37 | Y | F | -0.8012 | Soluble |
| 38 | T | F | -0.6371 | Soluble |
| 39 | M | F | 0.0000 | Buried |
| 40 | D | F | 0.0000 | Buried |
| 41 | W | F | 0.0000 | Buried |
| 42 | V | F | 0.0000 | Buried |
| 43 | R | F | 0.0000 | Buried |
| 44 | Q | F | -0.5574 | Soluble |
| 45 | A | F | -0.9046 | Soluble |
| 46 | P | F | -0.8794 | Soluble |
| 47 | G | F | -1.5029 | Soluble |
| 48 | K | F | -2.3295 | Soluble |
| 49 | G | F | -1.5058 | Soluble |
| 50 | L | F | 0.0000 | Buried |
| 51 | E | F | -0.7236 | Soluble |
| 52 | W | F | 0.0000 | Buried |
| 53 | V | F | 0.0000 | Buried |
| 54 | A | F | 0.0000 | Buried |
| 55 | D | F | 0.0000 | Buried |
| 56 | V | F | 0.0000 | Buried |
| 57 | N | F | -1.0829 | Soluble |
| 58 | P | F | 0.0000 | Buried |
| 59 | N | F | -2.0775 | Soluble |
| 62 | S | F | -1.2026 | Soluble |
| 63 | G | F | -1.4156 | Soluble |
| 64 | G | F | -0.5758 | Soluble |
| 65 | S | F | 0.2926 | Aggregation-prone |
| 66 | I | F | 1.1046 | Aggregation-prone |
| 67 | Y | F | 0.1566 | Aggregation-prone |
| 68 | N | F | -0.9370 | Soluble |
| 69 | Q | F | -2.1652 | Soluble |
| 70 | R | F | -2.5418 | Soluble |
| 71 | F | F | 0.0000 | Buried |
| 72 | K | F | -2.5059 | Soluble |
| 74 | G | F | -1.7941 | Soluble |
| 75 | R | F | -1.6321 | Soluble |
| 76 | F | F | -1.3912 | Soluble |
| 77 | T | F | -1.0393 | Soluble |
| 78 | L | F | 0.0000 | Buried |
| 79 | S | F | -0.7697 | Soluble |
| 80 | V | F | -1.5889 | Soluble |
| 81 | D | F | -2.5604 | Soluble |
| 82 | R | F | -3.1999 | Soluble |
| 83 | S | F | -2.3005 | Soluble |
| 84 | K | F | -2.9254 | Soluble |
| 85 | N | F | -2.3728 | Soluble |
| 86 | T | F | 0.0000 | Buried |
| 87 | L | F | 0.0000 | Buried |
| 88 | Y | F | 0.0000 | Buried |
| 89 | L | F | 0.0000 | Buried |
| 90 | Q | F | -1.7559 | Soluble |
| 91 | M | F | 0.0000 | Buried |
| 92 | N | F | -2.0898 | Soluble |
| 93 | S | F | -1.5684 | Soluble |
| 94 | L | F | 0.0000 | Buried |
| 95 | R | F | -2.4363 | Soluble |
| 96 | A | F | -1.5337 | Soluble |
| 97 | E | F | -1.6330 | Soluble |
| 98 | D | F | 0.0000 | Buried |
| 99 | T | F | -0.2899 | Soluble |
| 100 | A | F | 0.0000 | Buried |
| 101 | V | F | 0.6692 | Aggregation-prone |
| 102 | Y | F | 0.0000 | Buried |
| 103 | Y | F | 0.0000 | Buried |
| 104 | C | F | 0.0000 | Buried |
| 105 | A | F | 0.0000 | Buried |
| 106 | R | F | 0.0000 | Buried |
| 107 | N | F | 0.0000 | Buried |
| 108 | L | F | 0.0097 | Aggregation-prone |
| 109 | G | F | -0.3909 | Soluble |
| 110 | P | F | -0.5139 | Soluble |
| 112 | S | F | 0.1076 | Aggregation-prone |
| 113 | F | F | 0.0000 | Buried |
| 114 | Y | F | 0.3415 | Aggregation-prone |
| 115 | F | F | 0.0000 | Buried |
| 116 | D | F | 0.0000 | Buried |
| 117 | Y | F | -0.0956 | Soluble |
| 118 | W | F | -0.3673 | Soluble |
| 119 | G | F | 0.0000 | Buried |
| 120 | Q | F | -1.1698 | Soluble |
| 121 | G | F | 0.0000 | Buried |
| 122 | T | F | 0.5084 | Aggregation-prone |
| 123 | L | F | 1.2966 | Aggregation-prone |
| 124 | V | F | 0.0000 | Buried |
| 125 | T | F | 0.0275 | Aggregation-prone |
| 126 | V | F | 0.0000 | Buried |
| 127 | S | F | -0.6551 | Soluble |
| 128 | S | F | -0.9368 | Soluble |
| 129 | A | F | -0.5461 | Soluble |
| 130 | S | F | -0.5927 | Soluble |
| 131 | T | F | -0.6748 | Soluble |
| 132 | K | F | -1.0334 | Soluble |
| 133 | G | F | -1.2652 | Soluble |
| 134 | P | F | 0.0000 | Buried |
| 135 | S | F | -0.6027 | Soluble |
| 136 | V | F | 0.0000 | Buried |
| 137 | F | F | 0.0000 | Buried |
| 138 | P | F | -1.3355 | Soluble |
| 139 | L | F | 0.0000 | Buried |
| 140 | A | F | -0.9146 | Soluble |
| 141 | P | F | 0.0000 | Buried |
| 142 | S | F | -1.1118 | Soluble |
| 143 | S | F | -1.0425 | Soluble |
| 144 | K | F | -1.8689 | Soluble |
| 145 | S | F | -1.1564 | Soluble |
| 146 | T | F | -1.0024 | Soluble |
| 147 | S | F | -0.8502 | Soluble |
| 148 | G | F | -0.7246 | Soluble |
| 149 | G | F | -0.6631 | Soluble |
| 150 | T | F | -0.4965 | Soluble |
| 151 | A | F | 0.0000 | Buried |
| 152 | A | F | 0.0000 | Buried |
| 153 | L | F | 0.0000 | Buried |
| 154 | G | F | 0.0000 | Buried |
| 155 | C | F | 0.0000 | Buried |
| 156 | L | F | 0.0000 | Buried |
| 157 | V | F | 0.0000 | Buried |
| 158 | K | F | 0.0000 | Buried |
| 159 | D | F | -0.5084 | Soluble |
| 160 | Y | F | 0.0000 | Buried |
| 161 | F | F | 0.0000 | Buried |
| 162 | P | F | -0.8057 | Soluble |
| 163 | E | F | -1.3376 | Soluble |
| 164 | P | F | -1.2083 | Soluble |
| 165 | V | F | -0.6809 | Soluble |
| 166 | T | F | -0.6441 | Soluble |
| 167 | V | F | -0.0579 | Soluble |
| 168 | S | F | -0.2685 | Soluble |
| 169 | W | F | 0.0000 | Buried |
| 170 | N | F | -0.7829 | Soluble |
| 171 | S | F | -0.6973 | Soluble |
| 172 | G | F | -0.5780 | Soluble |
| 173 | A | F | -0.2460 | Soluble |
| 174 | L | F | -0.0538 | Soluble |
| 175 | T | F | -0.1528 | Soluble |
| 176 | S | F | -0.1939 | Soluble |
| 177 | G | F | -0.2186 | Soluble |
| 178 | V | F | 0.0914 | Aggregation-prone |
| 179 | H | F | -0.1270 | Soluble |
| 180 | T | F | 0.0160 | Aggregation-prone |
| 181 | F | F | 0.0000 | Buried |
| 182 | P | F | -0.3466 | Soluble |
| 183 | A | F | 0.0255 | Aggregation-prone |
| 184 | V | F | 0.2878 | Aggregation-prone |
| 185 | L | F | 0.7162 | Aggregation-prone |
| 186 | Q | F | 0.0923 | Aggregation-prone |
| 187 | S | F | -0.1302 | Soluble |
| 188 | S | F | -0.2635 | Soluble |
| 189 | G | F | -0.0713 | Soluble |
| 190 | L | F | -0.0406 | Soluble |
| 191 | Y | F | 0.1739 | Aggregation-prone |
| 192 | S | F | 0.0000 | Buried |
| 193 | L | F | 0.0000 | Buried |
| 194 | S | F | 0.0000 | Buried |
| 195 | S | F | 0.0000 | Buried |
| 196 | V | F | 0.0000 | Buried |
| 197 | V | F | 0.0000 | Buried |
| 198 | T | F | -0.1297 | Soluble |
| 199 | V | F | 0.0000 | Buried |
| 200 | P | F | -0.4186 | Soluble |
| 201 | S | F | -0.4989 | Soluble |
| 202 | S | F | -0.4920 | Soluble |
| 203 | S | F | -0.5310 | Soluble |
| 204 | L | F | -0.6366 | Soluble |
| 205 | G | F | -0.9061 | Soluble |
| 206 | T | F | -0.6619 | Soluble |
| 207 | Q | F | -1.0774 | Soluble |
| 208 | T | F | -1.0425 | Soluble |
| 209 | Y | F | 0.0000 | Buried |
| 210 | I | F | -1.5475 | Soluble |
| 211 | C | F | 0.0000 | Buried |
| 212 | N | F | -1.6251 | Soluble |
| 213 | V | F | 0.0000 | Buried |
| 214 | N | F | -1.8495 | Soluble |
| 215 | H | F | 0.0000 | Buried |
| 216 | K | F | -2.7576 | Soluble |
| 217 | P | F | -1.7001 | Soluble |
| 218 | S | F | -1.7603 | Soluble |
| 219 | N | F | -2.5039 | Soluble |
| 220 | T | F | -2.2427 | Soluble |
| 221 | K | F | -2.8914 | Soluble |
| 222 | V | F | -2.1897 | Soluble |
| 223 | D | F | -2.9933 | Soluble |
| 224 | K | F | -2.7653 | Soluble |
| 225 | K | F | -2.7127 | Soluble |
| 226 | V | F | 0.0000 | Buried |
| 227 | E | F | -2.9003 | Soluble |
| 228 | P | F | -1.9509 | Soluble |
| 229 | K | F | -2.2334 | Soluble |
| 230 | S | F | -1.1047 | Soluble |
| 231 | C | F | -0.6996 | Soluble |
| 1 | D | E | -1.9894 | Soluble |
| 2 | I | E | 0.0000 | Buried |
| 3 | Q | E | -2.1731 | Soluble |
| 4 | M | E | 0.0000 | Buried |
| 5 | T | E | -1.2634 | Soluble |
| 6 | Q | E | 0.0000 | Buried |
| 7 | S | E | -0.7847 | Soluble |
| 8 | P | E | -0.6455 | Soluble |
| 9 | S | E | -0.9103 | Soluble |
| 10 | S | E | -0.8769 | Soluble |
| 11 | L | E | -0.5646 | Soluble |
| 12 | S | E | -0.7258 | Soluble |
| 13 | A | E | 0.0000 | Buried |
| 14 | S | E | -0.4232 | Soluble |
| 15 | V | E | 0.2806 | Aggregation-prone |
| 16 | G | E | -0.6654 | Soluble |
| 17 | D | E | -1.3998 | Soluble |
| 18 | R | E | -2.1633 | Soluble |
| 19 | V | E | 0.0000 | Buried |
| 20 | T | E | -0.6047 | Soluble |
| 21 | I | E | 0.0000 | Buried |
| 22 | T | E | -0.7648 | Soluble |
| 23 | C | E | 0.0000 | Buried |
| 24 | K | E | -2.4074 | Soluble |
| 25 | A | E | -2.1864 | Soluble |
| 26 | S | E | -2.2043 | Soluble |
| 27 | Q | E | -2.7857 | Soluble |
| 28 | D | E | -2.3839 | Soluble |
| 29 | V | E | 0.0000 | Buried |
| 36 | S | E | -0.1915 | Soluble |
| 37 | I | E | 0.6978 | Aggregation-prone |
| 38 | G | E | 0.0000 | Buried |
| 39 | V | E | 0.0000 | Buried |
| 40 | A | E | 0.0000 | Buried |
| 41 | W | E | 0.0000 | Buried |
| 42 | Y | E | 0.0000 | Buried |
| 43 | Q | E | 0.0000 | Buried |
| 44 | Q | E | 0.0000 | Buried |
| 45 | K | E | -2.0467 | Soluble |
| 46 | P | E | -1.6249 | Soluble |
| 47 | G | E | -1.7598 | Soluble |
| 48 | K | E | -2.6476 | Soluble |
| 49 | A | E | -1.6300 | Soluble |
| 50 | P | E | 0.0000 | Buried |
| 51 | K | E | -1.3500 | Soluble |
| 52 | L | E | 0.0000 | Buried |
| 53 | L | E | 0.0000 | Buried |
| 54 | I | E | 0.0000 | Buried |
| 55 | Y | E | 0.7643 | Aggregation-prone |
| 56 | S | E | 0.7908 | Aggregation-prone |
| 57 | A | E | 0.0000 | Buried |
| 65 | S | E | 0.3144 | Aggregation-prone |
| 66 | Y | E | 0.7934 | Aggregation-prone |
| 67 | R | E | -0.5517 | Soluble |
| 68 | Y | E | -0.2135 | Soluble |
| 69 | T | E | -0.3077 | Soluble |
| 70 | G | E | -0.6793 | Soluble |
| 71 | V | E | 0.0000 | Buried |
| 72 | P | E | -0.5774 | Soluble |
| 74 | S | E | -0.6756 | Soluble |
| 75 | R | E | -0.8761 | Soluble |
| 76 | F | E | 0.0000 | Buried |
| 77 | S | E | -0.4489 | Soluble |
| 78 | G | E | -0.2189 | Soluble |
| 79 | S | E | -0.3324 | Soluble |
| 80 | G | E | -0.7684 | Soluble |
| 83 | S | E | -0.6757 | Soluble |
| 84 | G | E | -1.3874 | Soluble |
| 85 | T | E | -2.0337 | Soluble |
| 86 | D | E | -2.3554 | Soluble |
| 87 | F | E | 0.0000 | Buried |
| 88 | T | E | -0.7190 | Soluble |
| 89 | L | E | 0.0000 | Buried |
| 90 | T | E | -0.6130 | Soluble |
| 91 | I | E | 0.0000 | Buried |
| 92 | S | E | -1.2753 | Soluble |
| 93 | S | E | -1.1048 | Soluble |
| 94 | L | E | 0.0000 | Buried |
| 95 | Q | E | -0.9592 | Soluble |
| 96 | P | E | -0.9019 | Soluble |
| 97 | E | E | -1.9338 | Soluble |
| 98 | D | E | 0.0000 | Buried |
| 99 | F | E | -0.6634 | Soluble |
| 100 | A | E | 0.0000 | Buried |
| 101 | T | E | 0.0000 | Buried |
| 102 | Y | E | 0.0000 | Buried |
| 103 | Y | E | 0.0000 | Buried |
| 104 | C | E | 0.0000 | Buried |
| 105 | Q | E | 0.0000 | Buried |
| 106 | Q | E | 0.0000 | Buried |
| 107 | Y | E | 1.4566 | Aggregation-prone |
| 108 | Y | E | 1.9475 | Aggregation-prone |
| 109 | I | E | 1.5532 | Aggregation-prone |
| 114 | Y | E | 1.3944 | Aggregation-prone |
| 115 | P | E | 0.4865 | Aggregation-prone |
| 116 | Y | E | 0.6181 | Aggregation-prone |
| 117 | T | E | -0.1628 | Soluble |
| 118 | F | E | -0.3268 | Soluble |
| 119 | G | E | 0.0000 | Buried |
| 120 | Q | E | -1.6966 | Soluble |
| 121 | G | E | 0.0000 | Buried |
| 122 | T | E | 0.0000 | Buried |
| 123 | K | E | -1.9330 | Soluble |
| 124 | V | E | 0.0000 | Buried |
| 125 | E | E | -1.0148 | Soluble |
| 126 | I | E | -0.3699 | Soluble |
| 127 | K | E | -1.0061 | Soluble |
| 128 | R | E | -0.9665 | Soluble |
| 129 | T | E | 0.1757 | Aggregation-prone |
| 130 | V | E | 1.1278 | Aggregation-prone |
| 131 | A | E | 0.4905 | Aggregation-prone |
| 132 | A | E | 0.1597 | Aggregation-prone |
| 133 | P | E | 0.0000 | Buried |
| 134 | S | E | -0.1289 | Soluble |
| 135 | V | E | 0.0000 | Buried |
| 136 | F | E | 0.0000 | Buried |
| 137 | I | E | -0.1586 | Soluble |
| 138 | F | E | 0.0000 | Buried |
| 139 | P | E | -0.2628 | Soluble |
| 140 | P | E | -0.7595 | Soluble |
| 141 | S | E | -1.8203 | Soluble |
| 142 | D | E | -3.0413 | Soluble |
| 143 | E | E | -3.1880 | Soluble |
| 144 | Q | E | 0.0000 | Buried |
| 145 | L | E | -2.4067 | Soluble |
| 146 | K | E | -2.8593 | Soluble |
| 147 | S | E | -1.8070 | Soluble |
| 148 | G | E | -1.2206 | Soluble |
| 149 | T | E | -0.9322 | Soluble |
| 150 | A | E | 0.0000 | Buried |
| 151 | S | E | 0.0000 | Buried |
| 152 | V | E | 0.0000 | Buried |
| 153 | V | E | 0.0000 | Buried |
| 154 | C | E | 0.0000 | Buried |
| 155 | L | E | 0.0000 | Buried |
| 156 | L | E | 0.0000 | Buried |
| 157 | N | E | 0.0000 | Buried |
| 158 | N | E | -0.6281 | Soluble |
| 159 | F | E | 0.0000 | Buried |
| 160 | Y | E | 0.0000 | Buried |
| 161 | P | E | -1.0946 | Soluble |
| 162 | R | E | -1.8355 | Soluble |
| 163 | E | E | -2.7121 | Soluble |
| 164 | A | E | -2.0827 | Soluble |
| 165 | K | E | -2.3392 | Soluble |
| 166 | V | E | -1.1412 | Soluble |
| 167 | Q | E | -0.6365 | Soluble |
| 168 | W | E | 0.0000 | Buried |
| 169 | K | E | -0.6665 | Soluble |
| 170 | V | E | 0.0000 | Buried |
| 171 | D | E | -1.8827 | Soluble |
| 172 | N | E | -1.5701 | Soluble |
| 173 | A | E | -0.2707 | Soluble |
| 174 | L | E | 0.6451 | Aggregation-prone |
| 175 | Q | E | -0.1397 | Soluble |
| 176 | S | E | -0.3387 | Soluble |
| 177 | G | E | -0.7713 | Soluble |
| 178 | N | E | -0.9343 | Soluble |
| 179 | S | E | -1.2236 | Soluble |
| 180 | Q | E | -1.6522 | Soluble |
| 181 | E | E | -2.0127 | Soluble |
| 182 | S | E | -0.7944 | Soluble |
| 183 | V | E | -0.5017 | Soluble |
| 184 | T | E | -0.9784 | Soluble |
| 185 | E | E | -2.1076 | Soluble |
| 186 | Q | E | -1.8168 | Soluble |
| 187 | D | E | -1.9081 | Soluble |
| 188 | S | E | -1.7142 | Soluble |
| 189 | K | E | -2.2238 | Soluble |
| 190 | D | E | -1.6875 | Soluble |
| 191 | S | E | -1.6826 | Soluble |
| 192 | T | E | 0.0000 | Buried |
| 193 | Y | E | 0.0000 | Buried |
| 194 | S | E | 0.0000 | Buried |
| 195 | L | E | 0.0000 | Buried |
| 196 | S | E | 0.0000 | Buried |
| 197 | S | E | 0.0000 | Buried |
| 198 | T | E | -0.7571 | Soluble |
| 199 | L | E | 0.0000 | Buried |
| 200 | T | E | -0.5284 | Soluble |
| 201 | L | E | 0.0000 | Buried |
| 202 | S | E | -1.1137 | Soluble |
| 203 | K | E | -2.1006 | Soluble |
| 204 | A | E | -1.7921 | Soluble |
| 205 | D | E | -2.4323 | Soluble |
| 206 | Y | E | 0.0000 | Buried |
| 207 | E | E | -3.5563 | Soluble |
| 208 | K | E | -3.5649 | Soluble |
| 209 | H | E | -2.9759 | Soluble |
| 210 | K | E | -3.1601 | Soluble |
| 211 | V | E | -1.3922 | Soluble |
| 212 | Y | E | 0.0000 | Buried |
| 213 | A | E | 0.0000 | Buried |
| 214 | C | E | 0.0000 | Buried |
| 215 | E | E | -0.8510 | Soluble |
| 216 | V | E | 0.0000 | Buried |
| 217 | T | E | -1.1583 | Soluble |
| 218 | H | E | 0.0000 | Buried |
| 219 | Q | E | -1.4723 | Soluble |
| 220 | G | E | -0.1414 | Soluble |
| 221 | L | E | -0.0573 | Soluble |
| 222 | S | E | -0.3943 | Soluble |
| 223 | S | E | -0.3774 | Soluble |
| 224 | P | E | -0.5119 | Soluble |
| 225 | V | E | 0.1125 | Aggregation-prone |
| 226 | T | E | -0.4217 | Soluble |
| 227 | K | E | -0.7828 | Soluble |
| 228 | S | E | -0.7931 | Soluble |
| 229 | F | E | 0.0000 | Buried |
| 230 | N | E | -1.6791 | Soluble |
| 231 | R | E | -2.1965 | Soluble |
| 232 | G | E | -1.9837 | Soluble |
| 233 | E | E | -2.1877 | Soluble |
| 234 | C | E | -0.8564 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6823 | 2.5037 | CSV PDB |
| 4.5 | -0.7254 | 2.4154 | CSV PDB |
| 5.0 | -0.7759 | 2.3176 | CSV PDB |
| 5.5 | -0.8237 | 2.2489 | CSV PDB |
| 6.0 | -0.857 | 2.1902 | CSV PDB |
| 6.5 | -0.8663 | 2.1317 | CSV PDB |
| 7.0 | -0.851 | 2.0735 | CSV PDB |
| 7.5 | -0.8192 | 2.0168 | CSV PDB |
| 8.0 | -0.7784 | 1.9643 | CSV PDB |
| 8.5 | -0.7314 | 1.9507 | CSV PDB |
| 9.0 | -0.6778 | 1.9507 | CSV PDB |