Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYPFTSYGISWVRQAPGQGLEWMGWISTYNGNTNYAQKFQGRVTMTTDTSTTTGYMELRRLRSDDTAVYYCARDYTRGAWFGESLIGGFDNWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKEIVLTQSPGTLSLSPGERATLSCRASQTVSSTSLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQHDTSLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | B | -1.4064 | Soluble |
| 2 | V | B | -0.9046 | Soluble |
| 3 | Q | B | -1.6136 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | -0.3230 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.6553 | Soluble |
| 8 | G | B | -0.6259 | Soluble |
| 9 | A | B | -0.2468 | Soluble |
| 11 | E | B | -0.6689 | Soluble |
| 12 | V | B | -0.1208 | Soluble |
| 13 | K | B | -1.2725 | Soluble |
| 14 | K | B | -2.3092 | Soluble |
| 15 | P | B | -2.4265 | Soluble |
| 16 | G | B | -2.0214 | Soluble |
| 17 | A | B | -1.5408 | Soluble |
| 18 | S | B | -1.8352 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | K | B | -1.9520 | Soluble |
| 21 | V | B | 0.0000 | Buried |
| 22 | S | B | 0.0000 | Buried |
| 23 | C | B | 0.0000 | Buried |
| 24 | K | B | -1.0741 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.9982 | Soluble |
| 27 | G | B | -0.9559 | Soluble |
| 28 | Y | B | -0.4784 | Soluble |
| 29 | P | B | -0.3209 | Soluble |
| 30 | F | B | 0.0000 | Buried |
| 35 | T | B | 0.1857 | Aggregation-prone |
| 36 | S | B | 0.3768 | Aggregation-prone |
| 37 | Y | B | 0.4512 | Aggregation-prone |
| 38 | G | B | 0.0000 | Buried |
| 39 | I | B | 0.0000 | Buried |
| 40 | S | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -0.5852 | Soluble |
| 45 | A | B | -0.9671 | Soluble |
| 46 | P | B | -0.7669 | Soluble |
| 47 | G | B | -1.2263 | Soluble |
| 48 | Q | B | -1.7471 | Soluble |
| 49 | G | B | -1.0972 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -0.6561 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | M | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | W | B | 0.0000 | Buried |
| 56 | I | B | 0.0000 | Buried |
| 57 | S | B | 0.0000 | Buried |
| 58 | T | B | 0.0000 | Buried |
| 59 | Y | B | 0.3869 | Aggregation-prone |
| 62 | N | B | -0.9379 | Soluble |
| 63 | G | B | -1.3304 | Soluble |
| 64 | N | B | -1.4647 | Soluble |
| 65 | T | B | -1.1465 | Soluble |
| 66 | N | B | -1.1776 | Soluble |
| 67 | Y | B | -1.1125 | Soluble |
| 68 | A | B | -1.5894 | Soluble |
| 69 | Q | B | -2.5425 | Soluble |
| 70 | K | B | -2.6563 | Soluble |
| 71 | F | B | 0.0000 | Buried |
| 72 | Q | B | -2.2973 | Soluble |
| 74 | G | B | -1.8815 | Soluble |
| 75 | R | B | -1.9412 | Soluble |
| 76 | V | B | 0.0000 | Buried |
| 77 | T | B | -0.7421 | Soluble |
| 78 | M | B | 0.0000 | Buried |
| 79 | T | B | -0.3524 | Soluble |
| 80 | T | B | -0.5466 | Soluble |
| 81 | D | B | -0.8629 | Soluble |
| 82 | T | B | -0.4366 | Soluble |
| 83 | S | B | -0.5136 | Soluble |
| 84 | T | B | -0.6455 | Soluble |
| 85 | T | B | -0.7579 | Soluble |
| 86 | T | B | 0.0000 | Buried |
| 87 | G | B | 0.0000 | Buried |
| 88 | Y | B | -0.3361 | Soluble |
| 89 | M | B | 0.0000 | Buried |
| 90 | E | B | -1.2098 | Soluble |
| 91 | L | B | 0.0000 | Buried |
| 92 | R | B | -2.2892 | Soluble |
| 93 | R | B | -2.9600 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -3.4615 | Soluble |
| 96 | S | B | -2.3453 | Soluble |
| 97 | D | B | -2.5221 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.9042 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.2772 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | -0.2051 | Soluble |
| 107 | D | B | 0.0000 | Buried |
| 108 | Y | B | 0.9442 | Aggregation-prone |
| 109 | T | B | 0.0000 | Buried |
| 110 | R | B | -0.2621 | Soluble |
| 111 | G | B | 0.0000 | Buried |
| 111A | A | B | 0.0000 | Buried |
| 111B | W | B | 1.5187 | Aggregation-prone |
| 111C | F | B | 1.6034 | Aggregation-prone |
| 112D | G | B | -0.3331 | Soluble |
| 112C | E | B | -1.3397 | Soluble |
| 112B | S | B | -0.6169 | Soluble |
| 112A | L | B | 0.5180 | Aggregation-prone |
| 112 | I | B | 2.0346 | Aggregation-prone |
| 113 | G | B | 0.0000 | Buried |
| 114 | G | B | 0.0000 | Buried |
| 115 | F | B | 0.0000 | Buried |
| 116 | D | B | -0.6257 | Soluble |
| 117 | N | B | -0.9273 | Soluble |
| 118 | W | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.4968 | Soluble |
| 121 | G | B | -0.6482 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | L | B | 0.0963 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | 0.0000 | Buried |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -1.3165 | Soluble |
| 128 | S | B | -1.1353 | Soluble |
| 129 | A | B | -0.6891 | Soluble |
| 130 | S | B | -0.7765 | Soluble |
| 131 | T | B | -0.9198 | Soluble |
| 132 | K | B | -1.7103 | Soluble |
| 133 | G | B | -1.7771 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.4191 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -0.9526 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -1.0280 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -1.1488 | Soluble |
| 143 | S | B | -1.8517 | Soluble |
| 144 | K | B | -1.9557 | Soluble |
| 145 | S | B | -1.2337 | Soluble |
| 146 | T | B | -0.9869 | Soluble |
| 147 | S | B | -0.9344 | Soluble |
| 148 | G | B | -0.8379 | Soluble |
| 149 | G | B | -0.7454 | Soluble |
| 150 | T | B | -0.5042 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.7273 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.5096 | Soluble |
| 164 | P | B | -0.8129 | Soluble |
| 165 | V | B | -0.8396 | Soluble |
| 166 | T | B | -0.7852 | Soluble |
| 167 | V | B | -0.4445 | Soluble |
| 168 | S | B | -0.3761 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.5518 | Soluble |
| 171 | S | B | -0.5542 | Soluble |
| 172 | G | B | -0.5357 | Soluble |
| 173 | A | B | -0.1444 | Soluble |
| 174 | L | B | 0.0709 | Aggregation-prone |
| 175 | T | B | -0.1461 | Soluble |
| 176 | S | B | -0.2063 | Soluble |
| 177 | G | B | -0.1674 | Soluble |
| 178 | V | B | 0.1768 | Aggregation-prone |
| 179 | H | B | -0.3001 | Soluble |
| 180 | T | B | -0.1456 | Soluble |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.2425 | Soluble |
| 183 | A | B | 0.2237 | Aggregation-prone |
| 184 | V | B | 0.5346 | Aggregation-prone |
| 185 | L | B | 0.9718 | Aggregation-prone |
| 186 | Q | B | 0.1687 | Aggregation-prone |
| 187 | S | B | -0.1168 | Soluble |
| 188 | S | B | -0.2991 | Soluble |
| 189 | G | B | -0.1158 | Soluble |
| 190 | L | B | 0.0000 | Buried |
| 191 | Y | B | 0.0000 | Buried |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1087 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.6681 | Soluble |
| 201 | S | B | -0.5973 | Soluble |
| 202 | S | B | -0.7289 | Soluble |
| 203 | S | B | -0.6534 | Soluble |
| 204 | L | B | -0.7895 | Soluble |
| 205 | G | B | -0.9764 | Soluble |
| 206 | T | B | -0.7778 | Soluble |
| 207 | Q | B | -1.2580 | Soluble |
| 208 | T | B | -1.0010 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -0.8856 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.3687 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -2.4236 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.8825 | Soluble |
| 217 | P | B | -1.6552 | Soluble |
| 218 | S | B | -2.0585 | Soluble |
| 219 | N | B | -2.7481 | Soluble |
| 220 | T | B | -2.3292 | Soluble |
| 221 | K | B | -2.8053 | Soluble |
| 222 | V | B | -1.5617 | Soluble |
| 223 | D | B | -2.1150 | Soluble |
| 224 | K | B | -1.6868 | Soluble |
| 225 | K | B | -2.1659 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.4586 | Soluble |
| 228 | P | B | -1.8348 | Soluble |
| 229 | K | B | -2.2342 | Soluble |
| 1 | E | A | -1.7082 | Soluble |
| 2 | I | A | 0.0000 | Buried |
| 3 | V | A | 0.7201 | Aggregation-prone |
| 4 | L | A | 0.0000 | Buried |
| 5 | T | A | -0.6480 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.9268 | Soluble |
| 8 | P | A | -0.6057 | Soluble |
| 9 | G | A | -0.8326 | Soluble |
| 10 | T | A | -0.4753 | Soluble |
| 11 | L | A | -0.2665 | Soluble |
| 12 | S | A | -0.6324 | Soluble |
| 13 | L | A | -1.0627 | Soluble |
| 14 | S | A | -1.6813 | Soluble |
| 15 | P | A | -1.9812 | Soluble |
| 16 | G | A | -2.2337 | Soluble |
| 17 | E | A | -3.0422 | Soluble |
| 18 | R | A | -3.2357 | Soluble |
| 19 | A | A | 0.0000 | Buried |
| 20 | T | A | -0.5171 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.9372 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.3154 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.0454 | Soluble |
| 27 | Q | A | -1.7718 | Soluble |
| 28 | T | A | -1.2968 | Soluble |
| 29 | V | A | 0.0000 | Buried |
| 30 | S | A | -0.6228 | Soluble |
| 36 | S | A | -0.2182 | Soluble |
| 37 | T | A | 0.3543 | Aggregation-prone |
| 38 | S | A | 0.0000 | Buried |
| 39 | L | A | 0.0000 | Buried |
| 40 | A | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | -0.8870 | Soluble |
| 44 | Q | A | -1.1648 | Soluble |
| 45 | K | A | -1.5458 | Soluble |
| 46 | P | A | -1.3297 | Soluble |
| 47 | G | A | -1.4429 | Soluble |
| 48 | Q | A | -2.1303 | Soluble |
| 49 | A | A | -1.5567 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | R | A | -1.8989 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | 0.4014 | Aggregation-prone |
| 56 | G | A | 0.3802 | Aggregation-prone |
| 57 | A | A | 0.0000 | Buried |
| 65 | S | A | -0.6447 | Soluble |
| 66 | S | A | -0.4466 | Soluble |
| 67 | R | A | -1.5243 | Soluble |
| 68 | A | A | -0.8301 | Soluble |
| 69 | T | A | -0.5414 | Soluble |
| 70 | G | A | -0.7978 | Soluble |
| 71 | I | A | -0.9965 | Soluble |
| 72 | P | A | -1.2394 | Soluble |
| 74 | D | A | -2.1847 | Soluble |
| 75 | R | A | -2.0425 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -0.9176 | Soluble |
| 78 | G | A | -0.5347 | Soluble |
| 79 | S | A | -0.6648 | Soluble |
| 80 | G | A | -1.0353 | Soluble |
| 83 | S | A | -1.0066 | Soluble |
| 84 | G | A | -1.1138 | Soluble |
| 85 | T | A | -1.6461 | Soluble |
| 86 | D | A | -2.0594 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.7691 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.7960 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -2.3311 | Soluble |
| 93 | R | A | -3.3006 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | E | A | -2.5858 | Soluble |
| 96 | P | A | -1.7853 | Soluble |
| 97 | E | A | -2.2788 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | F | A | -0.7168 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | -0.2969 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | Q | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | H | A | 0.0000 | Buried |
| 108 | D | A | -1.2733 | Soluble |
| 114 | T | A | -1.1227 | Soluble |
| 115 | S | A | -0.9964 | Soluble |
| 116 | L | A | 0.0000 | Buried |
| 117 | T | A | -0.0939 | Soluble |
| 118 | F | A | 0.2558 | Aggregation-prone |
| 119 | G | A | 0.0000 | Buried |
| 120 | G | A | -0.6900 | Soluble |
| 121 | G | A | -0.7376 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -0.7795 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | E | A | 0.0000 | Buried |
| 126 | I | A | -0.8505 | Soluble |
| 127 | K | A | -1.6636 | Soluble |
| 128 | R | A | -1.1340 | Soluble |
| 129 | T | A | -0.1539 | Soluble |
| 130 | V | A | 0.4592 | Aggregation-prone |
| 131 | A | A | 0.1010 | Aggregation-prone |
| 132 | A | A | -0.0766 | Soluble |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.0865 | Soluble |
| 135 | V | A | 0.0000 | Buried |
| 136 | F | A | 0.1145 | Aggregation-prone |
| 137 | I | A | 0.0933 | Aggregation-prone |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.7424 | Soluble |
| 140 | P | A | -0.6692 | Soluble |
| 141 | S | A | -1.4359 | Soluble |
| 142 | D | A | -2.6747 | Soluble |
| 143 | E | A | -2.3419 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.1581 | Soluble |
| 146 | K | A | -2.6982 | Soluble |
| 147 | S | A | -1.7259 | Soluble |
| 148 | G | A | -1.4875 | Soluble |
| 149 | T | A | -1.2094 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -0.6825 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.2273 | Soluble |
| 162 | R | A | -1.8285 | Soluble |
| 163 | E | A | -2.6127 | Soluble |
| 164 | A | A | -1.9559 | Soluble |
| 165 | K | A | -2.1735 | Soluble |
| 166 | V | A | -1.2202 | Soluble |
| 167 | Q | A | -0.6954 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.6314 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -1.9443 | Soluble |
| 172 | N | A | -1.3654 | Soluble |
| 173 | A | A | -0.2747 | Soluble |
| 174 | L | A | 0.6808 | Aggregation-prone |
| 175 | Q | A | -0.1167 | Soluble |
| 176 | S | A | -0.4552 | Soluble |
| 177 | G | A | -0.8559 | Soluble |
| 178 | N | A | -0.7421 | Soluble |
| 179 | S | A | -0.9742 | Soluble |
| 180 | Q | A | -1.1098 | Soluble |
| 181 | E | A | -1.4078 | Soluble |
| 182 | S | A | -0.6800 | Soluble |
| 183 | V | A | -0.4183 | Soluble |
| 184 | T | A | -0.9711 | Soluble |
| 185 | E | A | -2.1185 | Soluble |
| 186 | Q | A | -1.7058 | Soluble |
| 187 | D | A | -1.9237 | Soluble |
| 188 | S | A | -1.7303 | Soluble |
| 189 | K | A | -2.2406 | Soluble |
| 190 | D | A | -1.6898 | Soluble |
| 191 | S | A | -1.7226 | Soluble |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.5278 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.3813 | Soluble |
| 201 | L | A | -0.6112 | Soluble |
| 202 | S | A | -1.2242 | Soluble |
| 203 | K | A | -2.0713 | Soluble |
| 204 | A | A | -1.8763 | Soluble |
| 205 | D | A | -2.3719 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.4777 | Soluble |
| 208 | K | A | -3.6207 | Soluble |
| 209 | H | A | -2.9801 | Soluble |
| 210 | K | A | -3.1470 | Soluble |
| 211 | V | A | -1.3362 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.9058 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.1515 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.6088 | Soluble |
| 220 | G | A | -0.4197 | Soluble |
| 221 | L | A | -0.2383 | Soluble |
| 222 | S | A | -0.4415 | Soluble |
| 223 | S | A | -0.4111 | Soluble |
| 224 | P | A | -0.5648 | Soluble |
| 225 | V | A | -0.0031 | Soluble |
| 226 | T | A | -0.4899 | Soluble |
| 227 | K | A | -0.6826 | Soluble |
| 228 | S | A | -0.5360 | Soluble |
| 229 | F | A | -0.9828 | Soluble |
| 230 | N | A | -1.9678 | Soluble |
| 231 | R | A | -2.7501 | Soluble |
| 232 | G | A | -2.2877 | Soluble |
| 233 | E | A | -2.6053 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7406 | 5.2503 | CSV PDB |
| 4.5 | -0.7792 | 5.1821 | CSV PDB |
| 5.0 | -0.8247 | 5.0737 | CSV PDB |
| 5.5 | -0.8679 | 4.9487 | CSV PDB |
| 6.0 | -0.8978 | 4.8833 | CSV PDB |
| 6.5 | -0.9061 | 4.8271 | CSV PDB |
| 7.0 | -0.8916 | 4.7892 | CSV PDB |
| 7.5 | -0.8613 | 4.7705 | CSV PDB |
| 8.0 | -0.8216 | 4.7632 | CSV PDB |
| 8.5 | -0.7753 | 4.7606 | CSV PDB |
| 9.0 | -0.7233 | 4.7594 | CSV PDB |