Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCARSPNPYYYDSSGYYYPGAFDIWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKGLTQPPSVSVAPGQTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDHYVFGTGTKVTVLRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), C (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | B | -1.1830 | Soluble |
| 2 | V | B | -0.3538 | Soluble |
| 3 | Q | B | -0.9010 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | 0.1801 | Aggregation-prone |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.5905 | Soluble |
| 8 | G | B | -0.7533 | Soluble |
| 9 | A | B | -0.8400 | Soluble |
| 11 | E | B | -1.2807 | Soluble |
| 12 | V | B | -0.7171 | Soluble |
| 13 | K | B | -1.6328 | Soluble |
| 14 | K | B | -2.5997 | Soluble |
| 15 | P | B | -2.5244 | Soluble |
| 16 | G | B | -2.3130 | Soluble |
| 17 | A | B | -1.7035 | Soluble |
| 18 | S | B | -1.8978 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | K | B | -2.1935 | Soluble |
| 21 | V | B | 0.0000 | Buried |
| 22 | S | B | -0.6881 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | K | B | -0.5782 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.3521 | Soluble |
| 27 | G | B | -0.6268 | Soluble |
| 28 | Y | B | -0.1328 | Soluble |
| 29 | T | B | -0.1042 | Soluble |
| 30 | F | B | 0.0000 | Buried |
| 35 | T | B | -0.6594 | Soluble |
| 36 | G | B | -0.1496 | Soluble |
| 37 | Y | B | 0.1327 | Aggregation-prone |
| 38 | Y | B | 0.0000 | Buried |
| 39 | M | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | -0.4636 | Soluble |
| 44 | Q | B | -0.7181 | Soluble |
| 45 | A | B | -1.0453 | Soluble |
| 46 | P | B | -0.8621 | Soluble |
| 47 | G | B | -1.2604 | Soluble |
| 48 | Q | B | -1.7102 | Soluble |
| 49 | G | B | -1.1296 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -0.6506 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | M | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | W | B | 0.0012 | Aggregation-prone |
| 56 | I | B | 0.0000 | Buried |
| 57 | N | B | 0.0000 | Buried |
| 58 | P | B | 0.0000 | Buried |
| 59 | N | B | -1.6021 | Soluble |
| 62 | S | B | -1.1114 | Soluble |
| 63 | G | B | -1.0533 | Soluble |
| 64 | G | B | -0.6923 | Soluble |
| 65 | T | B | -0.2759 | Soluble |
| 66 | N | B | -0.7567 | Soluble |
| 67 | Y | B | -1.1729 | Soluble |
| 68 | A | B | 0.0000 | Buried |
| 69 | Q | B | -2.7146 | Soluble |
| 70 | K | B | -2.7072 | Soluble |
| 71 | F | B | 0.0000 | Buried |
| 72 | Q | B | -2.3915 | Soluble |
| 74 | G | B | -1.8321 | Soluble |
| 75 | R | B | -1.7278 | Soluble |
| 76 | V | B | 0.0000 | Buried |
| 77 | T | B | -0.8912 | Soluble |
| 78 | M | B | 0.0000 | Buried |
| 79 | T | B | -0.7324 | Soluble |
| 80 | R | B | -1.1957 | Soluble |
| 81 | D | B | -1.1824 | Soluble |
| 82 | T | B | -0.5506 | Soluble |
| 83 | S | B | 0.2611 | Aggregation-prone |
| 84 | I | B | 1.1866 | Aggregation-prone |
| 85 | S | B | 0.0858 | Aggregation-prone |
| 86 | T | B | 0.0000 | Buried |
| 87 | A | B | 0.0000 | Buried |
| 88 | Y | B | -0.9685 | Soluble |
| 89 | M | B | 0.0000 | Buried |
| 90 | E | B | -1.7148 | Soluble |
| 91 | L | B | 0.0000 | Buried |
| 92 | S | B | -1.9671 | Soluble |
| 93 | R | B | -2.8535 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -3.4285 | Soluble |
| 96 | S | B | -2.3695 | Soluble |
| 97 | D | B | -2.4818 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -1.0880 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.1001 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | 0.0000 | Buried |
| 107 | S | B | 0.0000 | Buried |
| 108 | P | B | 0.0283 | Aggregation-prone |
| 109 | N | B | 0.4574 | Aggregation-prone |
| 110 | P | B | 1.0595 | Aggregation-prone |
| 111 | Y | B | 1.8723 | Aggregation-prone |
| 111A | Y | B | 2.1202 | Aggregation-prone |
| 111B | Y | B | 1.6693 | Aggregation-prone |
| 111C | D | B | 0.5636 | Aggregation-prone |
| 111D | S | B | 0.3899 | Aggregation-prone |
| 112E | S | B | 0.4500 | Aggregation-prone |
| 112D | G | B | 0.1291 | Aggregation-prone |
| 112C | Y | B | 1.0735 | Aggregation-prone |
| 112B | Y | B | 0.4397 | Aggregation-prone |
| 112A | Y | B | 0.7568 | Aggregation-prone |
| 112 | P | B | -0.0978 | Soluble |
| 113 | G | B | 0.0000 | Buried |
| 114 | A | B | 0.0000 | Buried |
| 115 | F | B | 0.0000 | Buried |
| 116 | D | B | -0.1665 | Soluble |
| 117 | I | B | 0.1912 | Aggregation-prone |
| 118 | W | B | -0.0352 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.2553 | Soluble |
| 121 | G | B | -0.6544 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | M | B | -0.2402 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | 0.0000 | Buried |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -1.3615 | Soluble |
| 128 | S | B | -0.9835 | Soluble |
| 129 | A | B | -0.5657 | Soluble |
| 130 | S | B | -0.6723 | Soluble |
| 131 | T | B | -0.6446 | Soluble |
| 132 | K | B | -1.1287 | Soluble |
| 133 | G | B | -1.3657 | Soluble |
| 134 | P | B | -0.5800 | Soluble |
| 135 | S | B | -0.2038 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | -0.5309 | Soluble |
| 138 | P | B | -0.8645 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -1.2243 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -1.1490 | Soluble |
| 143 | S | B | -0.9143 | Soluble |
| 144 | K | B | -1.5347 | Soluble |
| 145 | S | B | 0.0000 | Buried |
| 146 | T | B | -0.8689 | Soluble |
| 147 | S | B | -0.8896 | Soluble |
| 148 | G | B | -0.8566 | Soluble |
| 149 | G | B | -0.9262 | Soluble |
| 150 | T | B | -0.6291 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.3112 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.4325 | Soluble |
| 164 | P | B | -0.6965 | Soluble |
| 165 | V | B | -0.6910 | Soluble |
| 166 | T | B | -0.6223 | Soluble |
| 167 | V | B | -0.2466 | Soluble |
| 168 | S | B | -0.3834 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.6395 | Soluble |
| 171 | S | B | -0.5987 | Soluble |
| 172 | G | B | -0.4591 | Soluble |
| 173 | A | B | -0.1921 | Soluble |
| 174 | L | B | 0.0338 | Aggregation-prone |
| 175 | T | B | -0.1505 | Soluble |
| 176 | S | B | -0.1752 | Soluble |
| 177 | G | B | -0.1890 | Soluble |
| 178 | V | B | 0.1782 | Aggregation-prone |
| 179 | H | B | -0.1846 | Soluble |
| 180 | T | B | 0.0260 | Aggregation-prone |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.3238 | Soluble |
| 183 | A | B | 0.1982 | Aggregation-prone |
| 184 | V | B | 0.4282 | Aggregation-prone |
| 185 | L | B | 1.1394 | Aggregation-prone |
| 186 | Q | B | 0.2781 | Aggregation-prone |
| 187 | S | B | -0.0704 | Soluble |
| 188 | S | B | -0.2076 | Soluble |
| 189 | G | B | 0.0624 | Aggregation-prone |
| 190 | L | B | 0.1922 | Aggregation-prone |
| 191 | Y | B | 0.4879 | Aggregation-prone |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1385 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.6196 | Soluble |
| 201 | S | B | -0.5936 | Soluble |
| 202 | S | B | -0.5570 | Soluble |
| 203 | S | B | -0.5616 | Soluble |
| 204 | L | B | -0.7295 | Soluble |
| 205 | G | B | -0.9258 | Soluble |
| 206 | T | B | -0.6309 | Soluble |
| 207 | Q | B | -1.0553 | Soluble |
| 208 | T | B | -0.9697 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -1.0310 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.4378 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -2.1572 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.9336 | Soluble |
| 217 | P | B | -1.7525 | Soluble |
| 218 | S | B | -1.9112 | Soluble |
| 219 | N | B | -2.5861 | Soluble |
| 220 | T | B | -2.1481 | Soluble |
| 221 | K | B | -2.8367 | Soluble |
| 222 | V | B | -1.7907 | Soluble |
| 223 | D | B | -2.4899 | Soluble |
| 224 | K | B | -1.9872 | Soluble |
| 225 | K | B | -2.1133 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.6481 | Soluble |
| 228 | P | B | -1.8494 | Soluble |
| 229 | K | B | -2.0657 | Soluble |
| 3 | G | C | -0.6557 | Soluble |
| 4 | L | C | 0.0000 | Buried |
| 5 | T | C | -0.3023 | Soluble |
| 6 | Q | C | 0.0000 | Buried |
| 7 | P | C | -0.5242 | Soluble |
| 8 | P | C | -0.5538 | Soluble |
| 9 | S | C | -0.5622 | Soluble |
| 11 | V | C | -0.6093 | Soluble |
| 12 | S | C | -0.4133 | Soluble |
| 13 | V | C | 0.0000 | Buried |
| 14 | A | C | -0.8415 | Soluble |
| 15 | P | C | -1.6593 | Soluble |
| 16 | G | C | -2.3114 | Soluble |
| 17 | Q | C | -2.2776 | Soluble |
| 18 | T | C | -2.0127 | Soluble |
| 19 | A | C | 0.0000 | Buried |
| 20 | R | C | -1.8797 | Soluble |
| 21 | I | C | 0.0000 | Buried |
| 22 | T | C | -0.7178 | Soluble |
| 23 | C | C | 0.0000 | Buried |
| 24 | G | C | -1.1322 | Soluble |
| 25 | G | C | -1.7947 | Soluble |
| 26 | N | C | -2.6686 | Soluble |
| 27 | N | C | -2.8637 | Soluble |
| 28 | I | C | 0.0000 | Buried |
| 29 | G | C | -2.0112 | Soluble |
| 36 | S | C | -1.5497 | Soluble |
| 37 | K | C | -1.7426 | Soluble |
| 38 | S | C | -1.1285 | Soluble |
| 39 | V | C | 0.0000 | Buried |
| 40 | H | C | 0.0000 | Buried |
| 41 | W | C | 0.0000 | Buried |
| 42 | Y | C | 0.0000 | Buried |
| 43 | Q | C | 0.0000 | Buried |
| 44 | Q | C | -0.7416 | Soluble |
| 45 | K | C | -1.4319 | Soluble |
| 46 | P | C | -1.4824 | Soluble |
| 47 | G | C | -1.5162 | Soluble |
| 48 | Q | C | -1.8309 | Soluble |
| 49 | A | C | -0.8516 | Soluble |
| 50 | P | C | 0.0000 | Buried |
| 51 | V | C | 0.8209 | Aggregation-prone |
| 52 | L | C | 0.0000 | Buried |
| 53 | V | C | 0.0000 | Buried |
| 54 | V | C | 0.0000 | Buried |
| 55 | Y | C | -1.2247 | Soluble |
| 56 | D | C | -2.0282 | Soluble |
| 57 | D | C | -1.7796 | Soluble |
| 65 | S | C | -1.6569 | Soluble |
| 66 | D | C | -2.1770 | Soluble |
| 67 | R | C | -1.8287 | Soluble |
| 68 | P | C | -0.7130 | Soluble |
| 69 | S | C | -0.6628 | Soluble |
| 70 | G | C | -0.7458 | Soluble |
| 71 | I | C | -0.5231 | Soluble |
| 72 | P | C | -1.1791 | Soluble |
| 74 | E | C | -2.0852 | Soluble |
| 75 | R | C | -1.5295 | Soluble |
| 76 | F | C | 0.0000 | Buried |
| 77 | S | C | -1.2536 | Soluble |
| 78 | G | C | -1.1454 | Soluble |
| 79 | S | C | -0.9500 | Soluble |
| 80 | N | C | -1.4134 | Soluble |
| 83 | S | C | -1.4274 | Soluble |
| 84 | G | C | -2.1135 | Soluble |
| 85 | N | C | -2.6427 | Soluble |
| 86 | T | C | -1.4646 | Soluble |
| 87 | A | C | 0.0000 | Buried |
| 88 | T | C | -0.7569 | Soluble |
| 89 | L | C | 0.0000 | Buried |
| 90 | T | C | -1.0784 | Soluble |
| 91 | I | C | 0.0000 | Buried |
| 92 | S | C | -2.1587 | Soluble |
| 93 | R | C | -2.9645 | Soluble |
| 94 | V | C | 0.0000 | Buried |
| 95 | E | C | -2.5764 | Soluble |
| 96 | A | C | -1.7302 | Soluble |
| 97 | G | C | -1.2326 | Soluble |
| 98 | D | C | 0.0000 | Buried |
| 99 | E | C | 0.0000 | Buried |
| 100 | A | C | 0.0000 | Buried |
| 101 | D | C | -0.8658 | Soluble |
| 102 | Y | C | 0.0000 | Buried |
| 103 | Y | C | 0.0000 | Buried |
| 104 | C | C | 0.0000 | Buried |
| 105 | Q | C | 0.0000 | Buried |
| 106 | V | C | 0.0000 | Buried |
| 107 | W | C | 0.0000 | Buried |
| 108 | D | C | -1.2662 | Soluble |
| 109 | S | C | -1.1141 | Soluble |
| 110 | S | C | -0.9869 | Soluble |
| 113 | S | C | -1.3498 | Soluble |
| 114 | D | C | -2.0465 | Soluble |
| 115 | H | C | -1.2805 | Soluble |
| 116 | Y | C | 0.0000 | Buried |
| 117 | V | C | -0.1980 | Soluble |
| 118 | F | C | 0.0000 | Buried |
| 119 | G | C | 0.0000 | Buried |
| 120 | T | C | -0.4781 | Soluble |
| 121 | G | C | 0.0000 | Buried |
| 122 | T | C | 0.0000 | Buried |
| 123 | K | C | -0.9277 | Soluble |
| 124 | V | C | 0.0000 | Buried |
| 125 | T | C | -0.2407 | Soluble |
| 126 | V | C | 0.0000 | Buried |
| 127 | L | C | 0.3370 | Aggregation-prone |
| 128 | R | C | -0.1053 | Soluble |
| 129 | T | C | 0.4903 | Aggregation-prone |
| 130 | V | C | 0.8222 | Aggregation-prone |
| 131 | A | C | 0.0321 | Aggregation-prone |
| 132 | A | C | -0.0463 | Soluble |
| 133 | P | C | 0.0000 | Buried |
| 134 | S | C | -0.2010 | Soluble |
| 135 | V | C | 0.0000 | Buried |
| 136 | F | C | 0.0000 | Buried |
| 137 | I | C | 0.0000 | Buried |
| 138 | F | C | 0.0000 | Buried |
| 139 | P | C | -0.8822 | Soluble |
| 140 | P | C | 0.0000 | Buried |
| 141 | S | C | -1.6547 | Soluble |
| 142 | D | C | -2.7775 | Soluble |
| 143 | E | C | -2.6414 | Soluble |
| 144 | Q | C | 0.0000 | Buried |
| 145 | L | C | -2.2283 | Soluble |
| 146 | K | C | -2.7505 | Soluble |
| 147 | S | C | -1.6842 | Soluble |
| 148 | G | C | -1.3211 | Soluble |
| 149 | T | C | -0.9898 | Soluble |
| 150 | A | C | 0.0000 | Buried |
| 151 | S | C | 0.0000 | Buried |
| 152 | V | C | 0.0000 | Buried |
| 153 | V | C | 0.0000 | Buried |
| 154 | C | C | 0.0000 | Buried |
| 155 | L | C | 0.0000 | Buried |
| 156 | L | C | 0.0000 | Buried |
| 157 | N | C | 0.0000 | Buried |
| 158 | N | C | -0.7994 | Soluble |
| 159 | F | C | 0.0000 | Buried |
| 160 | Y | C | 0.0000 | Buried |
| 161 | P | C | -1.3810 | Soluble |
| 162 | R | C | -3.0269 | Soluble |
| 163 | E | C | -3.2814 | Soluble |
| 164 | A | C | -2.3673 | Soluble |
| 165 | K | C | -2.3927 | Soluble |
| 166 | V | C | -1.0167 | Soluble |
| 167 | Q | C | -0.3993 | Soluble |
| 168 | W | C | 0.0000 | Buried |
| 169 | K | C | -0.4093 | Soluble |
| 170 | V | C | 0.0000 | Buried |
| 171 | D | C | -1.6590 | Soluble |
| 172 | N | C | -1.4636 | Soluble |
| 173 | A | C | -0.2323 | Soluble |
| 174 | L | C | 0.7441 | Aggregation-prone |
| 175 | Q | C | -0.0263 | Soluble |
| 176 | S | C | -0.4160 | Soluble |
| 177 | G | C | -0.8903 | Soluble |
| 178 | N | C | -0.6485 | Soluble |
| 179 | S | C | -1.1119 | Soluble |
| 180 | Q | C | -1.4080 | Soluble |
| 181 | E | C | -1.9594 | Soluble |
| 182 | S | C | -0.9560 | Soluble |
| 183 | V | C | -0.7003 | Soluble |
| 184 | T | C | -0.7382 | Soluble |
| 185 | E | C | -1.3553 | Soluble |
| 186 | Q | C | 0.0000 | Buried |
| 187 | D | C | -1.5790 | Soluble |
| 188 | S | C | -1.8131 | Soluble |
| 189 | K | C | -2.4027 | Soluble |
| 190 | D | C | -1.8052 | Soluble |
| 191 | S | C | 0.0000 | Buried |
| 192 | T | C | 0.0000 | Buried |
| 193 | Y | C | 0.0000 | Buried |
| 194 | S | C | 0.0000 | Buried |
| 195 | L | C | 0.0000 | Buried |
| 196 | S | C | 0.0000 | Buried |
| 197 | S | C | 0.0000 | Buried |
| 198 | T | C | -0.6753 | Soluble |
| 199 | L | C | 0.0000 | Buried |
| 200 | T | C | -0.4172 | Soluble |
| 201 | L | C | -0.7084 | Soluble |
| 202 | S | C | -1.1272 | Soluble |
| 203 | K | C | -2.1484 | Soluble |
| 204 | A | C | -2.0032 | Soluble |
| 205 | D | C | -2.7167 | Soluble |
| 206 | Y | C | 0.0000 | Buried |
| 207 | E | C | -3.7563 | Soluble |
| 208 | K | C | -3.6506 | Soluble |
| 209 | H | C | -3.0071 | Soluble |
| 210 | K | C | -3.0381 | Soluble |
| 211 | V | C | -1.2703 | Soluble |
| 212 | Y | C | 0.0000 | Buried |
| 213 | A | C | 0.0000 | Buried |
| 214 | C | C | 0.0000 | Buried |
| 215 | E | C | -0.6290 | Soluble |
| 216 | V | C | 0.0000 | Buried |
| 217 | T | C | -1.1623 | Soluble |
| 218 | H | C | 0.0000 | Buried |
| 219 | Q | C | -1.6957 | Soluble |
| 220 | G | C | -0.3261 | Soluble |
| 221 | L | C | -0.2141 | Soluble |
| 222 | S | C | -0.4636 | Soluble |
| 223 | S | C | -0.4254 | Soluble |
| 224 | P | C | -0.5611 | Soluble |
| 225 | V | C | -0.0240 | Soluble |
| 226 | T | C | -0.3859 | Soluble |
| 227 | K | C | -0.8206 | Soluble |
| 228 | S | C | -0.7001 | Soluble |
| 229 | F | C | 0.0000 | Buried |
| 230 | N | C | -1.6802 | Soluble |
| 231 | R | C | -2.5317 | Soluble |
| 232 | G | C | -1.9817 | Soluble |
| 233 | E | C | -2.0432 | Soluble |
| 234 | C | C | -0.9252 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6653 | 2.1636 | CSV PDB |
| 4.5 | -0.7085 | 2.1334 | CSV PDB |
| 5.0 | -0.7584 | 2.1013 | CSV PDB |
| 5.5 | -0.8055 | 2.0685 | CSV PDB |
| 6.0 | -0.8397 | 2.0354 | CSV PDB |
| 6.5 | -0.8535 | 2.0024 | CSV PDB |
| 7.0 | -0.8471 | 1.9697 | CSV PDB |
| 7.5 | -0.8271 | 1.9377 | CSV PDB |
| 8.0 | -0.7989 | 1.908 | CSV PDB |
| 8.5 | -0.7637 | 1.8824 | CSV PDB |
| 9.0 | -0.7217 | 1.8594 | CSV PDB |