Calculation Parameters
| Chain Sequence(s) |
QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSDILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | B | -1.4625 | Soluble |
| 2 | V | B | -0.8815 | Soluble |
| 3 | Q | B | -1.5683 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | K | B | -2.2039 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.7677 | Soluble |
| 8 | G | B | -1.0525 | Soluble |
| 9 | P | B | -0.4669 | Soluble |
| 11 | G | B | -0.3989 | Soluble |
| 12 | L | B | 0.0653 | Aggregation-prone |
| 13 | V | B | -0.4637 | Soluble |
| 14 | Q | B | -0.9811 | Soluble |
| 15 | P | B | -1.3244 | Soluble |
| 16 | S | B | -1.3937 | Soluble |
| 17 | Q | B | -1.7418 | Soluble |
| 18 | S | B | -1.6551 | Soluble |
| 19 | L | B | 0.0000 | Buried |
| 20 | S | B | -0.8650 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.5305 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | T | B | -1.1438 | Soluble |
| 25 | V | B | 0.0000 | Buried |
| 26 | S | B | -1.1915 | Soluble |
| 27 | G | B | -0.9843 | Soluble |
| 28 | F | B | -0.5521 | Soluble |
| 29 | S | B | -0.8849 | Soluble |
| 30 | L | B | 0.0000 | Buried |
| 35 | T | B | -0.9170 | Soluble |
| 36 | N | B | -0.8363 | Soluble |
| 37 | Y | B | 0.4622 | Aggregation-prone |
| 38 | G | B | 0.0000 | Buried |
| 39 | V | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -0.6873 | Soluble |
| 45 | S | B | -1.0617 | Soluble |
| 46 | P | B | -0.9688 | Soluble |
| 47 | G | B | -1.4697 | Soluble |
| 48 | K | B | -2.1758 | Soluble |
| 49 | G | B | -1.2271 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -0.8540 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | V | B | 0.0000 | Buried |
| 56 | I | B | 0.0000 | Buried |
| 57 | W | B | -0.5059 | Soluble |
| 58 | S | B | -0.6100 | Soluble |
| 59 | G | B | -1.2185 | Soluble |
| 63 | G | B | -1.5145 | Soluble |
| 64 | N | B | -1.8283 | Soluble |
| 65 | T | B | -1.2837 | Soluble |
| 66 | D | B | -0.9721 | Soluble |
| 67 | Y | B | -0.3340 | Soluble |
| 68 | N | B | 0.0000 | Buried |
| 69 | T | B | -0.2840 | Soluble |
| 70 | P | B | -0.3608 | Soluble |
| 71 | F | B | 0.0000 | Buried |
| 72 | T | B | -0.4510 | Soluble |
| 74 | S | B | -0.6509 | Soluble |
| 75 | R | B | -1.2387 | Soluble |
| 76 | L | B | 0.0000 | Buried |
| 77 | S | B | -1.2289 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | N | B | -1.7991 | Soluble |
| 80 | K | B | -1.5039 | Soluble |
| 81 | D | B | -1.9665 | Soluble |
| 82 | N | B | -2.2915 | Soluble |
| 83 | S | B | -1.7421 | Soluble |
| 84 | K | B | -2.4393 | Soluble |
| 85 | S | B | -1.6745 | Soluble |
| 86 | Q | B | -1.6061 | Soluble |
| 87 | V | B | 0.0000 | Buried |
| 88 | F | B | -0.3412 | Soluble |
| 89 | F | B | 0.0000 | Buried |
| 90 | K | B | -1.9978 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | N | B | -2.1840 | Soluble |
| 93 | S | B | -1.4910 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -1.8676 | Soluble |
| 96 | S | B | -1.3437 | Soluble |
| 97 | N | B | -1.7018 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.4700 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | I | B | 0.4986 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | 0.0000 | Buried |
| 107 | A | B | 0.0000 | Buried |
| 108 | L | B | 1.0344 | Aggregation-prone |
| 109 | T | B | 1.1536 | Aggregation-prone |
| 110 | Y | B | 1.8670 | Aggregation-prone |
| 111 | Y | B | 1.9715 | Aggregation-prone |
| 112 | D | B | 0.0000 | Buried |
| 113 | Y | B | 0.6165 | Aggregation-prone |
| 114 | E | B | 0.0000 | Buried |
| 115 | F | B | 0.0000 | Buried |
| 116 | A | B | 0.2727 | Aggregation-prone |
| 117 | Y | B | 0.2039 | Aggregation-prone |
| 118 | W | B | -0.4719 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.7803 | Soluble |
| 121 | G | B | -0.8804 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | L | B | 0.1929 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | -0.1832 | Soluble |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -0.4795 | Soluble |
| 128 | A | B | -0.2683 | Soluble |
| 129 | A | B | -0.2021 | Soluble |
| 130 | S | B | -0.4135 | Soluble |
| 131 | T | B | -0.6588 | Soluble |
| 132 | K | B | -1.1429 | Soluble |
| 133 | G | B | -1.3277 | Soluble |
| 134 | P | B | -0.5015 | Soluble |
| 135 | S | B | -0.2944 | Soluble |
| 136 | V | B | -0.3445 | Soluble |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.2038 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -0.9328 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -1.4305 | Soluble |
| 143 | S | B | -1.3453 | Soluble |
| 144 | K | B | -1.9718 | Soluble |
| 145 | S | B | 0.0000 | Buried |
| 146 | T | B | -0.9774 | Soluble |
| 147 | S | B | -0.8195 | Soluble |
| 148 | G | B | -0.7745 | Soluble |
| 149 | G | B | -0.8061 | Soluble |
| 150 | T | B | -0.5892 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.2741 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.4037 | Soluble |
| 164 | P | B | -0.5496 | Soluble |
| 165 | V | B | -0.6517 | Soluble |
| 166 | T | B | -0.6488 | Soluble |
| 167 | V | B | -0.3733 | Soluble |
| 168 | S | B | -0.3800 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.6703 | Soluble |
| 171 | S | B | -0.6162 | Soluble |
| 172 | G | B | -0.4452 | Soluble |
| 173 | A | B | -0.1959 | Soluble |
| 174 | L | B | 0.0392 | Aggregation-prone |
| 175 | T | B | -0.1455 | Soluble |
| 176 | S | B | -0.1745 | Soluble |
| 177 | G | B | -0.1885 | Soluble |
| 178 | V | B | 0.1812 | Aggregation-prone |
| 179 | H | B | -0.3139 | Soluble |
| 180 | T | B | 0.0181 | Aggregation-prone |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.3690 | Soluble |
| 183 | A | B | 0.1837 | Aggregation-prone |
| 184 | V | B | 0.4179 | Aggregation-prone |
| 185 | L | B | 1.1781 | Aggregation-prone |
| 186 | Q | B | 0.2948 | Aggregation-prone |
| 187 | S | B | -0.0590 | Soluble |
| 188 | S | B | -0.1924 | Soluble |
| 189 | G | B | 0.0550 | Aggregation-prone |
| 190 | L | B | 0.2218 | Aggregation-prone |
| 191 | Y | B | 0.5502 | Aggregation-prone |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1306 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.5119 | Soluble |
| 201 | S | B | -0.5391 | Soluble |
| 202 | S | B | -0.5796 | Soluble |
| 203 | S | B | -0.6291 | Soluble |
| 204 | L | B | -0.7539 | Soluble |
| 205 | G | B | -0.9303 | Soluble |
| 206 | T | B | -0.7407 | Soluble |
| 207 | Q | B | -1.2050 | Soluble |
| 208 | T | B | -1.0632 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -1.1757 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.4252 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -2.1383 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.8552 | Soluble |
| 217 | P | B | -1.5924 | Soluble |
| 218 | S | B | -1.8286 | Soluble |
| 219 | N | B | -2.6578 | Soluble |
| 220 | T | B | -2.0849 | Soluble |
| 221 | K | B | -2.6899 | Soluble |
| 222 | V | B | -1.4035 | Soluble |
| 223 | D | B | -2.3229 | Soluble |
| 224 | K | B | -2.0287 | Soluble |
| 225 | R | B | -2.2492 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.5124 | Soluble |
| 228 | P | B | -1.7874 | Soluble |
| 229 | K | B | -2.2762 | Soluble |
| 230 | S | B | -1.5150 | Soluble |
| 1 | D | A | -1.4924 | Soluble |
| 2 | I | A | 0.0000 | Buried |
| 3 | L | A | 0.5892 | Aggregation-prone |
| 4 | L | A | 0.0000 | Buried |
| 5 | T | A | -0.3637 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | 0.0819 | Aggregation-prone |
| 8 | P | A | 0.7419 | Aggregation-prone |
| 9 | V | A | 1.7637 | Aggregation-prone |
| 10 | I | A | 1.1788 | Aggregation-prone |
| 11 | L | A | 0.5154 | Aggregation-prone |
| 12 | S | A | -0.1960 | Soluble |
| 13 | V | A | -1.1794 | Soluble |
| 14 | S | A | -1.8145 | Soluble |
| 15 | P | A | -2.0419 | Soluble |
| 16 | G | A | -2.1952 | Soluble |
| 17 | E | A | -3.0963 | Soluble |
| 18 | R | A | -3.3120 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | S | A | -0.9454 | Soluble |
| 21 | F | A | 0.0000 | Buried |
| 22 | S | A | -0.8674 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.5440 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.0692 | Soluble |
| 27 | Q | A | -1.9524 | Soluble |
| 28 | S | A | -1.6771 | Soluble |
| 29 | I | A | 0.0000 | Buried |
| 36 | G | A | -1.0574 | Soluble |
| 37 | T | A | -0.7617 | Soluble |
| 38 | N | A | -0.8142 | Soluble |
| 39 | I | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | -1.1220 | Soluble |
| 45 | R | A | -1.7764 | Soluble |
| 46 | T | A | -1.6067 | Soluble |
| 47 | N | A | -1.7436 | Soluble |
| 48 | G | A | -1.4024 | Soluble |
| 49 | S | A | -0.9225 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | R | A | -0.6239 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | K | A | -0.7718 | Soluble |
| 56 | Y | A | -0.5677 | Soluble |
| 57 | A | A | 0.0000 | Buried |
| 65 | S | A | -1.2944 | Soluble |
| 66 | E | A | -2.0178 | Soluble |
| 67 | S | A | -1.2069 | Soluble |
| 68 | I | A | -0.5333 | Soluble |
| 69 | S | A | -0.3425 | Soluble |
| 70 | G | A | -0.4747 | Soluble |
| 71 | I | A | -0.2633 | Soluble |
| 72 | P | A | -0.3404 | Soluble |
| 74 | S | A | -0.5876 | Soluble |
| 75 | R | A | -1.1163 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -0.9430 | Soluble |
| 78 | G | A | -0.7706 | Soluble |
| 79 | S | A | -0.8701 | Soluble |
| 80 | G | A | -1.1267 | Soluble |
| 83 | S | A | -0.9317 | Soluble |
| 84 | G | A | -1.3817 | Soluble |
| 85 | T | A | -1.9850 | Soluble |
| 86 | D | A | -2.6632 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.9246 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | S | A | -0.9309 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | N | A | -2.4784 | Soluble |
| 93 | S | A | -2.4025 | Soluble |
| 94 | V | A | 0.0000 | Buried |
| 95 | E | A | -2.3207 | Soluble |
| 96 | S | A | -2.1177 | Soluble |
| 97 | E | A | -2.0434 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | I | A | 0.0000 | Buried |
| 100 | A | A | -1.2430 | Soluble |
| 101 | D | A | -0.6922 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | Q | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | N | A | -0.6809 | Soluble |
| 108 | N | A | -1.4347 | Soluble |
| 109 | N | A | -1.3052 | Soluble |
| 114 | W | A | 0.0438 | Aggregation-prone |
| 115 | P | A | -0.3309 | Soluble |
| 116 | T | A | 0.0000 | Buried |
| 117 | T | A | -0.1874 | Soluble |
| 118 | F | A | 0.2567 | Aggregation-prone |
| 119 | G | A | 0.0000 | Buried |
| 120 | A | A | -0.2570 | Soluble |
| 121 | G | A | -0.2275 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -0.7320 | Soluble |
| 124 | L | A | 0.0000 | Buried |
| 125 | E | A | -1.0106 | Soluble |
| 126 | L | A | 0.0000 | Buried |
| 127 | K | A | -1.7634 | Soluble |
| 128 | R | A | -1.3697 | Soluble |
| 129 | T | A | -0.2426 | Soluble |
| 130 | V | A | 0.3092 | Aggregation-prone |
| 131 | A | A | 0.1538 | Aggregation-prone |
| 132 | A | A | -0.0290 | Soluble |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.1554 | Soluble |
| 135 | V | A | 0.0000 | Buried |
| 136 | F | A | 0.0000 | Buried |
| 137 | I | A | 0.0000 | Buried |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.5162 | Soluble |
| 140 | P | A | -0.8809 | Soluble |
| 141 | S | A | -1.9496 | Soluble |
| 142 | D | A | -3.0923 | Soluble |
| 143 | E | A | -3.2498 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.4329 | Soluble |
| 146 | K | A | -2.9344 | Soluble |
| 147 | S | A | -1.8445 | Soluble |
| 148 | G | A | -1.3379 | Soluble |
| 149 | T | A | -0.9120 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -0.6744 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | -0.9168 | Soluble |
| 161 | P | A | -1.4243 | Soluble |
| 162 | R | A | -2.3941 | Soluble |
| 163 | E | A | -2.8898 | Soluble |
| 164 | A | A | -2.1885 | Soluble |
| 165 | K | A | -2.3659 | Soluble |
| 166 | V | A | -1.0931 | Soluble |
| 167 | Q | A | -0.5854 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.6292 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -1.9440 | Soluble |
| 172 | N | A | -1.5836 | Soluble |
| 173 | A | A | -0.3243 | Soluble |
| 174 | L | A | 0.6243 | Aggregation-prone |
| 175 | Q | A | -0.3623 | Soluble |
| 176 | S | A | -0.6879 | Soluble |
| 177 | G | A | -1.3672 | Soluble |
| 178 | N | A | -1.7669 | Soluble |
| 179 | S | A | -1.6347 | Soluble |
| 180 | Q | A | -1.6779 | Soluble |
| 181 | E | A | -1.9748 | Soluble |
| 182 | S | A | -0.9955 | Soluble |
| 183 | V | A | -0.8292 | Soluble |
| 184 | T | A | -1.0560 | Soluble |
| 185 | E | A | -2.2114 | Soluble |
| 186 | Q | A | 0.0000 | Buried |
| 187 | D | A | -2.1110 | Soluble |
| 188 | S | A | -2.2770 | Soluble |
| 189 | K | A | -2.5724 | Soluble |
| 190 | D | A | -1.7815 | Soluble |
| 191 | S | A | 0.0000 | Buried |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.8391 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.7106 | Soluble |
| 201 | L | A | -0.8309 | Soluble |
| 202 | S | A | -1.0051 | Soluble |
| 203 | K | A | -2.0264 | Soluble |
| 204 | A | A | -1.7925 | Soluble |
| 205 | D | A | -2.3866 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.2405 | Soluble |
| 208 | K | A | -3.4572 | Soluble |
| 209 | H | A | -2.8181 | Soluble |
| 210 | K | A | -2.3768 | Soluble |
| 211 | V | A | -0.8874 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | -0.7013 | Soluble |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.9004 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.2025 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.6900 | Soluble |
| 220 | G | A | -0.4401 | Soluble |
| 221 | L | A | -0.2325 | Soluble |
| 222 | S | A | -0.4473 | Soluble |
| 223 | S | A | -0.4252 | Soluble |
| 224 | P | A | -0.5332 | Soluble |
| 225 | V | A | 0.0051 | Aggregation-prone |
| 226 | T | A | -0.5050 | Soluble |
| 227 | K | A | -1.0033 | Soluble |
| 228 | S | A | -0.7531 | Soluble |
| 229 | F | A | -0.7563 | Soluble |
| 230 | N | A | -1.1549 | Soluble |
| 231 | R | A | -1.7424 | Soluble |
| 232 | G | A | -1.1201 | Soluble |
| 233 | A | A | -0.5655 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.712 | 2.8005 | CSV PDB |
| 4.5 | -0.7494 | 2.7513 | CSV PDB |
| 5.0 | -0.7938 | 2.6814 | CSV PDB |
| 5.5 | -0.8358 | 2.6004 | CSV PDB |
| 6.0 | -0.8644 | 2.515 | CSV PDB |
| 6.5 | -0.8708 | 2.4282 | CSV PDB |
| 7.0 | -0.8549 | 2.3409 | CSV PDB |
| 7.5 | -0.8243 | 2.2539 | CSV PDB |
| 8.0 | -0.7858 | 2.1917 | CSV PDB |
| 8.5 | -0.742 | 2.1897 | CSV PDB |
| 9.0 | -0.6931 | 2.1835 | CSV PDB |