Calculation Parameters
| Chain Sequence(s) |
QVQLQESGPGLVKPSETLSVTCSVSGDSMNNYYWTWIRQSPGKGLEWIGYISDRESATYNPSLNSRVVISRDTSKNQLSLKLNSVTPADTAVYYCATARRGQRIYGVVSFGEFFYYYSMDVWGKGTTVTVSSASTKGPSVFPLAPSSKTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCLSVALGETARISCGRQALGSRAVQWYQHRPGQAPILLIYNNQDRPSGIPERFSGTPDINFGTRATLTISGVEAGDEADYYCHMWDSRSGFSWSFGGATRLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTEC
input.pdb
|
| Selected Chain(s) | D (Heavy), E (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | D | -1.7129 | Soluble |
| 2 | V | D | -1.4598 | Soluble |
| 3 | Q | D | -1.9849 | Soluble |
| 4 | L | D | 0.0000 | Buried |
| 5 | Q | D | -1.4959 | Soluble |
| 6 | E | D | 0.0000 | Buried |
| 7 | S | D | -0.7852 | Soluble |
| 8 | G | D | -0.4400 | Soluble |
| 9 | P | D | -0.5103 | Soluble |
| 11 | G | D | -0.5213 | Soluble |
| 12 | L | D | -0.3921 | Soluble |
| 13 | V | D | 0.0000 | Buried |
| 14 | K | D | -1.9291 | Soluble |
| 15 | P | D | -1.3840 | Soluble |
| 16 | S | D | -1.4175 | Soluble |
| 17 | E | D | -1.9524 | Soluble |
| 18 | T | D | -1.4386 | Soluble |
| 19 | L | D | 0.0000 | Buried |
| 20 | S | D | -0.6779 | Soluble |
| 21 | V | D | 0.0000 | Buried |
| 22 | T | D | -0.4964 | Soluble |
| 23 | C | D | 0.0000 | Buried |
| 24 | S | D | -0.9656 | Soluble |
| 25 | V | D | -1.2935 | Soluble |
| 26 | S | D | -1.7640 | Soluble |
| 27 | G | D | -1.9029 | Soluble |
| 28 | D | D | -2.8613 | Soluble |
| 29 | S | D | -1.8253 | Soluble |
| 30 | M | D | 0.0000 | Buried |
| 35 | N | D | -2.1228 | Soluble |
| 36 | N | D | -1.9852 | Soluble |
| 37 | Y | D | -1.1841 | Soluble |
| 38 | Y | D | -1.0975 | Soluble |
| 39 | W | D | 0.0000 | Buried |
| 40 | T | D | 0.0000 | Buried |
| 41 | W | D | 0.0000 | Buried |
| 42 | I | D | 0.0000 | Buried |
| 43 | R | D | 0.0000 | Buried |
| 44 | Q | D | -0.9591 | Soluble |
| 45 | S | D | -0.9389 | Soluble |
| 46 | P | D | -1.0628 | Soluble |
| 47 | G | D | -1.4985 | Soluble |
| 48 | K | D | -2.3159 | Soluble |
| 49 | G | D | -1.5900 | Soluble |
| 50 | L | D | 0.0000 | Buried |
| 51 | E | D | -1.1318 | Soluble |
| 52 | W | D | 0.0000 | Buried |
| 53 | I | D | 0.0000 | Buried |
| 54 | G | D | 0.0000 | Buried |
| 55 | Y | D | 0.0000 | Buried |
| 56 | I | D | 0.0000 | Buried |
| 57 | S | D | 0.0000 | Buried |
| 58 | D | D | -2.2704 | Soluble |
| 59 | R | D | -2.9983 | Soluble |
| 63 | E | D | -2.9030 | Soluble |
| 64 | S | D | -1.6269 | Soluble |
| 65 | A | D | -0.4527 | Soluble |
| 66 | T | D | 0.2062 | Aggregation-prone |
| 67 | Y | D | 0.6048 | Aggregation-prone |
| 68 | N | D | 0.0000 | Buried |
| 69 | P | D | -0.4097 | Soluble |
| 70 | S | D | -0.4989 | Soluble |
| 71 | L | D | -0.5528 | Soluble |
| 72 | N | D | -1.4692 | Soluble |
| 74 | S | D | -0.8346 | Soluble |
| 75 | R | D | -0.9662 | Soluble |
| 76 | V | D | 0.0000 | Buried |
| 77 | V | D | 0.8307 | Aggregation-prone |
| 78 | I | D | 0.3493 | Aggregation-prone |
| 79 | S | D | -0.4947 | Soluble |
| 80 | R | D | -1.2405 | Soluble |
| 81 | D | D | -1.4774 | Soluble |
| 82 | T | D | -1.5840 | Soluble |
| 83 | S | D | -1.6095 | Soluble |
| 84 | K | D | -2.4508 | Soluble |
| 85 | N | D | -2.1157 | Soluble |
| 86 | Q | D | -1.5259 | Soluble |
| 87 | L | D | 0.0000 | Buried |
| 88 | S | D | -0.3936 | Soluble |
| 89 | L | D | 0.0000 | Buried |
| 90 | K | D | -0.8593 | Soluble |
| 91 | L | D | 0.0000 | Buried |
| 92 | N | D | -1.4933 | Soluble |
| 93 | S | D | -1.2337 | Soluble |
| 94 | V | D | 0.0000 | Buried |
| 95 | T | D | -0.7712 | Soluble |
| 96 | P | D | -0.4890 | Soluble |
| 97 | A | D | -0.1008 | Soluble |
| 98 | D | D | 0.0000 | Buried |
| 99 | T | D | -0.1323 | Soluble |
| 100 | A | D | 0.0000 | Buried |
| 101 | V | D | -0.0405 | Soluble |
| 102 | Y | D | 0.0000 | Buried |
| 103 | Y | D | 0.0000 | Buried |
| 104 | C | D | 0.0000 | Buried |
| 105 | A | D | 0.0000 | Buried |
| 106 | T | D | 0.0000 | Buried |
| 107 | A | D | 0.0000 | Buried |
| 108 | R | D | -1.8533 | Soluble |
| 109 | R | D | -2.0569 | Soluble |
| 110 | G | D | -1.0947 | Soluble |
| 111 | Q | D | -0.2835 | Soluble |
| 111A | R | D | 0.2784 | Aggregation-prone |
| 111B | I | D | 1.8687 | Aggregation-prone |
| 111C | Y | D | 1.6082 | Aggregation-prone |
| 111D | G | D | 1.6433 | Aggregation-prone |
| 111E | V | D | 2.6720 | Aggregation-prone |
| 111F | V | D | 2.6935 | Aggregation-prone |
| 112G | S | D | 1.5042 | Aggregation-prone |
| 112F | F | D | 2.3198 | Aggregation-prone |
| 112E | G | D | 1.2106 | Aggregation-prone |
| 112D | E | D | 1.1684 | Aggregation-prone |
| 112C | F | D | 1.5234 | Aggregation-prone |
| 112B | F | D | 0.9887 | Aggregation-prone |
| 112A | Y | D | 0.7896 | Aggregation-prone |
| 112 | Y | D | 0.0000 | Buried |
| 113 | Y | D | -0.6989 | Soluble |
| 114 | S | D | 0.0000 | Buried |
| 115 | M | D | 0.0000 | Buried |
| 116 | D | D | -0.4805 | Soluble |
| 117 | V | D | -0.2239 | Soluble |
| 118 | W | D | -0.4852 | Soluble |
| 119 | G | D | -1.3432 | Soluble |
| 120 | K | D | -2.2388 | Soluble |
| 121 | G | D | -1.1757 | Soluble |
| 122 | T | D | 0.0000 | Buried |
| 123 | T | D | -0.1378 | Soluble |
| 124 | V | D | 0.0000 | Buried |
| 125 | T | D | -0.3256 | Soluble |
| 126 | V | D | 0.0000 | Buried |
| 127 | S | D | -0.7502 | Soluble |
| 128 | S | D | -0.7864 | Soluble |
| 129 | A | D | -0.5943 | Soluble |
| 130 | S | D | -0.8000 | Soluble |
| 131 | T | D | -1.0629 | Soluble |
| 132 | K | D | -1.7824 | Soluble |
| 133 | G | D | -1.5713 | Soluble |
| 134 | P | D | -0.8280 | Soluble |
| 135 | S | D | -0.4101 | Soluble |
| 136 | V | D | 0.0000 | Buried |
| 137 | F | D | -0.6432 | Soluble |
| 138 | P | D | 0.0000 | Buried |
| 139 | L | D | 0.0000 | Buried |
| 140 | A | D | 0.0000 | Buried |
| 141 | P | D | -0.7558 | Soluble |
| 142 | S | D | -0.7600 | Soluble |
| 143 | S | D | -1.1862 | Soluble |
| 144 | K | D | -1.8544 | Soluble |
| 145 | T | D | -0.7973 | Soluble |
| 146 | A | D | 0.0000 | Buried |
| 147 | A | D | -0.4171 | Soluble |
| 148 | L | D | 0.0000 | Buried |
| 149 | G | D | 0.0000 | Buried |
| 150 | C | D | 0.0000 | Buried |
| 151 | L | D | 0.0000 | Buried |
| 152 | V | D | 0.0000 | Buried |
| 153 | K | D | 0.0000 | Buried |
| 154 | D | D | -0.8735 | Soluble |
| 155 | Y | D | 0.0000 | Buried |
| 156 | F | D | -0.5799 | Soluble |
| 157 | P | D | 0.0000 | Buried |
| 158 | E | D | -0.4462 | Soluble |
| 159 | P | D | -0.4929 | Soluble |
| 160 | V | D | -0.5509 | Soluble |
| 161 | T | D | -0.7199 | Soluble |
| 162 | V | D | 0.0000 | Buried |
| 163 | S | D | -0.3409 | Soluble |
| 164 | W | D | 0.0000 | Buried |
| 165 | N | D | -0.8573 | Soluble |
| 166 | S | D | -0.6605 | Soluble |
| 167 | G | D | -0.3506 | Soluble |
| 168 | A | D | -0.1625 | Soluble |
| 169 | L | D | -0.0070 | Soluble |
| 170 | T | D | -0.0958 | Soluble |
| 171 | S | D | -0.2113 | Soluble |
| 172 | G | D | -0.2163 | Soluble |
| 173 | V | D | 0.1844 | Aggregation-prone |
| 174 | H | D | -0.1354 | Soluble |
| 175 | T | D | 0.0382 | Aggregation-prone |
| 176 | F | D | -0.1385 | Soluble |
| 177 | P | D | 0.0890 | Aggregation-prone |
| 178 | A | D | 0.1772 | Aggregation-prone |
| 179 | V | D | 0.0000 | Buried |
| 180 | L | D | 0.8158 | Aggregation-prone |
| 181 | Q | D | 0.0443 | Aggregation-prone |
| 182 | S | D | -0.2529 | Soluble |
| 183 | S | D | -0.4062 | Soluble |
| 184 | G | D | -0.3339 | Soluble |
| 185 | L | D | -0.1913 | Soluble |
| 186 | Y | D | 0.2012 | Aggregation-prone |
| 187 | S | D | 0.0000 | Buried |
| 188 | L | D | 0.0000 | Buried |
| 189 | S | D | 0.0000 | Buried |
| 190 | S | D | 0.0000 | Buried |
| 191 | V | D | 0.2186 | Aggregation-prone |
| 192 | V | D | 0.0000 | Buried |
| 193 | T | D | -0.3544 | Soluble |
| 194 | V | D | 0.0000 | Buried |
| 195 | P | D | -0.7817 | Soluble |
| 196 | S | D | -0.9107 | Soluble |
| 197 | S | D | -0.4851 | Soluble |
| 198 | S | D | -0.7131 | Soluble |
| 199 | L | D | 0.0000 | Buried |
| 200 | G | D | -1.0764 | Soluble |
| 201 | T | D | -0.9648 | Soluble |
| 202 | Q | D | -1.3857 | Soluble |
| 203 | T | D | -1.1607 | Soluble |
| 204 | Y | D | 0.0000 | Buried |
| 205 | I | D | -1.5821 | Soluble |
| 206 | C | D | 0.0000 | Buried |
| 207 | N | D | -1.7100 | Soluble |
| 208 | V | D | 0.0000 | Buried |
| 209 | N | D | -2.6353 | Soluble |
| 210 | H | D | 0.0000 | Buried |
| 211 | K | D | -2.8309 | Soluble |
| 212 | P | D | -1.7945 | Soluble |
| 213 | S | D | -2.0275 | Soluble |
| 214 | N | D | -2.7127 | Soluble |
| 215 | T | D | -2.3286 | Soluble |
| 216 | K | D | -3.0184 | Soluble |
| 217 | V | D | -1.9821 | Soluble |
| 218 | D | D | -2.9544 | Soluble |
| 219 | K | D | -2.3743 | Soluble |
| 220 | R | D | -2.6942 | Soluble |
| 221 | V | D | 0.0000 | Buried |
| 222 | E | D | -1.7986 | Soluble |
| 223 | P | D | -1.2427 | Soluble |
| 224 | K | D | -0.9667 | Soluble |
| 225 | S | D | -0.7879 | Soluble |
| 226 | C | D | -0.8569 | Soluble |
| 11 | L | E | 0.1856 | Aggregation-prone |
| 12 | S | E | 0.2794 | Aggregation-prone |
| 13 | V | E | 0.0256 | Aggregation-prone |
| 14 | A | E | 0.0009 | Aggregation-prone |
| 15 | L | E | -0.4088 | Soluble |
| 16 | G | E | -1.3923 | Soluble |
| 17 | E | E | -1.8906 | Soluble |
| 18 | T | E | -1.4659 | Soluble |
| 19 | A | E | 0.0000 | Buried |
| 20 | R | E | -1.9347 | Soluble |
| 21 | I | E | 0.0000 | Buried |
| 22 | S | E | -1.0777 | Soluble |
| 23 | C | E | -1.1812 | Soluble |
| 24 | G | E | -1.4632 | Soluble |
| 25 | R | E | -1.6922 | Soluble |
| 26 | Q | E | -1.7538 | Soluble |
| 27 | A | E | -1.3120 | Soluble |
| 28 | L | E | -0.4175 | Soluble |
| 29 | G | E | -0.3364 | Soluble |
| 36 | S | E | 0.2019 | Aggregation-prone |
| 37 | R | E | -0.1043 | Soluble |
| 38 | A | E | 0.0000 | Buried |
| 39 | V | E | 0.0000 | Buried |
| 40 | Q | E | 0.0000 | Buried |
| 41 | W | E | 0.0000 | Buried |
| 42 | Y | E | 0.0000 | Buried |
| 43 | Q | E | 0.0000 | Buried |
| 44 | H | E | 0.0000 | Buried |
| 45 | R | E | -1.2633 | Soluble |
| 46 | P | E | -1.3251 | Soluble |
| 47 | G | E | -1.5187 | Soluble |
| 48 | Q | E | -1.8392 | Soluble |
| 49 | A | E | -0.9556 | Soluble |
| 50 | P | E | 0.0000 | Buried |
| 51 | I | E | 0.3759 | Aggregation-prone |
| 52 | L | E | 0.0000 | Buried |
| 53 | L | E | 0.0000 | Buried |
| 54 | I | E | 0.0000 | Buried |
| 55 | Y | E | -0.8645 | Soluble |
| 56 | N | E | -1.0728 | Soluble |
| 57 | N | E | -1.2350 | Soluble |
| 65 | Q | E | -1.9138 | Soluble |
| 66 | D | E | -1.7321 | Soluble |
| 67 | R | E | -2.0040 | Soluble |
| 68 | P | E | -1.2643 | Soluble |
| 69 | S | E | -0.9160 | Soluble |
| 70 | G | E | -0.7702 | Soluble |
| 71 | I | E | -0.7903 | Soluble |
| 72 | P | E | -1.3551 | Soluble |
| 74 | E | E | -2.3745 | Soluble |
| 75 | R | E | -1.7426 | Soluble |
| 76 | F | E | 0.0000 | Buried |
| 77 | S | E | -1.1690 | Soluble |
| 78 | G | E | -0.9565 | Soluble |
| 79 | T | E | -1.2841 | Soluble |
| 80 | P | E | -1.5946 | Soluble |
| 81 | D | E | -2.0762 | Soluble |
| 81A | I | E | -0.9424 | Soluble |
| 82 | N | E | -0.8456 | Soluble |
| 83 | F | E | 0.9297 | Aggregation-prone |
| 84 | G | E | -0.1984 | Soluble |
| 85 | T | E | -1.0280 | Soluble |
| 86 | R | E | -2.1102 | Soluble |
| 87 | A | E | 0.0000 | Buried |
| 88 | T | E | -1.0496 | Soluble |
| 89 | L | E | 0.0000 | Buried |
| 90 | T | E | -0.8835 | Soluble |
| 91 | I | E | 0.0000 | Buried |
| 92 | S | E | -1.5997 | Soluble |
| 93 | G | E | -1.4324 | Soluble |
| 94 | V | E | 0.0000 | Buried |
| 95 | E | E | -1.9925 | Soluble |
| 96 | A | E | -1.0913 | Soluble |
| 97 | G | E | -1.0553 | Soluble |
| 98 | D | E | 0.0000 | Buried |
| 99 | E | E | -1.0564 | Soluble |
| 100 | A | E | 0.0000 | Buried |
| 101 | D | E | -1.1175 | Soluble |
| 102 | Y | E | 0.0000 | Buried |
| 103 | Y | E | 0.0000 | Buried |
| 104 | C | E | 0.0000 | Buried |
| 105 | H | E | 0.0000 | Buried |
| 106 | M | E | 0.0000 | Buried |
| 107 | W | E | 0.0000 | Buried |
| 108 | D | E | 0.0000 | Buried |
| 109 | S | E | -0.6877 | Soluble |
| 110 | R | E | -1.8071 | Soluble |
| 112 | S | E | -0.7944 | Soluble |
| 113 | G | E | -0.0169 | Soluble |
| 114 | F | E | 1.5253 | Aggregation-prone |
| 115 | S | E | 0.7547 | Aggregation-prone |
| 116 | W | E | 0.2127 | Aggregation-prone |
| 117 | S | E | -0.2121 | Soluble |
| 118 | F | E | -0.4834 | Soluble |
| 119 | G | E | -0.9402 | Soluble |
| 120 | G | E | -1.2190 | Soluble |
| 121 | A | E | -0.8086 | Soluble |
| 122 | T | E | -0.8114 | Soluble |
| 123 | R | E | -1.6981 | Soluble |
| 124 | L | E | 0.0000 | Buried |
| 125 | T | E | 0.0219 | Aggregation-prone |
| 126 | V | E | 0.0000 | Buried |
| 127 | L | E | 1.0103 | Aggregation-prone |
| 128 | G | E | 0.0240 | Aggregation-prone |
| 129 | Q | E | -0.6654 | Soluble |
| 130 | P | E | -1.3264 | Soluble |
| 131 | K | E | -2.0866 | Soluble |
| 132 | A | E | -1.3740 | Soluble |
| 133 | A | E | -0.7444 | Soluble |
| 134 | P | E | -0.5174 | Soluble |
| 135 | S | E | -0.2984 | Soluble |
| 136 | V | E | 0.0000 | Buried |
| 137 | T | E | -0.2066 | Soluble |
| 138 | L | E | -0.0433 | Soluble |
| 139 | F | E | 0.0000 | Buried |
| 140 | P | E | 0.0000 | Buried |
| 141 | P | E | 0.0000 | Buried |
| 142 | S | E | 0.0000 | Buried |
| 143 | S | E | -1.1278 | Soluble |
| 144 | E | E | -1.7773 | Soluble |
| 145 | E | E | 0.0000 | Buried |
| 146 | L | E | -1.2011 | Soluble |
| 147 | Q | E | -1.8262 | Soluble |
| 148 | A | E | -1.4178 | Soluble |
| 149 | N | E | -2.2194 | Soluble |
| 150 | K | E | -1.7910 | Soluble |
| 151 | A | E | 0.0000 | Buried |
| 152 | T | E | 0.0000 | Buried |
| 153 | L | E | 0.0000 | Buried |
| 154 | V | E | 0.0000 | Buried |
| 155 | C | E | 0.0000 | Buried |
| 156 | L | E | 0.0000 | Buried |
| 157 | I | E | 0.0000 | Buried |
| 158 | S | E | -0.6200 | Soluble |
| 159 | D | E | -1.4380 | Soluble |
| 160 | F | E | 0.0000 | Buried |
| 161 | Y | E | -1.1611 | Soluble |
| 162 | P | E | -0.8753 | Soluble |
| 163 | G | E | 0.0000 | Buried |
| 164 | A | E | -0.1851 | Soluble |
| 165 | V | E | -0.1412 | Soluble |
| 166 | T | E | -0.1224 | Soluble |
| 167 | V | E | 0.3324 | Aggregation-prone |
| 168 | A | E | -0.4013 | Soluble |
| 169 | W | E | 0.0000 | Buried |
| 170 | K | E | -1.0554 | Soluble |
| 171 | A | E | 0.0000 | Buried |
| 172 | D | E | -1.3979 | Soluble |
| 173 | S | E | -0.7366 | Soluble |
| 174 | S | E | -0.6250 | Soluble |
| 175 | P | E | -0.7975 | Soluble |
| 176 | V | E | -0.5502 | Soluble |
| 177 | K | E | -1.5184 | Soluble |
| 178 | A | E | -0.6934 | Soluble |
| 179 | G | E | -0.5095 | Soluble |
| 180 | V | E | -0.2949 | Soluble |
| 181 | E | E | -0.2149 | Soluble |
| 182 | T | E | 0.1213 | Aggregation-prone |
| 183 | T | E | 0.0626 | Aggregation-prone |
| 184 | T | E | -0.1642 | Soluble |
| 185 | P | E | -0.4565 | Soluble |
| 186 | S | E | -0.8777 | Soluble |
| 187 | K | E | -1.9107 | Soluble |
| 188 | Q | E | -1.5575 | Soluble |
| 189 | S | E | -1.2191 | Soluble |
| 190 | N | E | -1.4575 | Soluble |
| 191 | N | E | -1.4244 | Soluble |
| 192 | K | E | -1.7496 | Soluble |
| 193 | Y | E | -1.0953 | Soluble |
| 194 | A | E | 0.0000 | Buried |
| 195 | A | E | -0.2196 | Soluble |
| 196 | S | E | 0.0000 | Buried |
| 197 | S | E | 0.0000 | Buried |
| 198 | Y | E | 0.0000 | Buried |
| 199 | L | E | 0.0000 | Buried |
| 200 | S | E | -0.3505 | Soluble |
| 201 | L | E | 0.0000 | Buried |
| 202 | T | E | -1.6526 | Soluble |
| 203 | P | E | -2.1472 | Soluble |
| 204 | E | E | -2.9720 | Soluble |
| 205 | Q | E | -2.1512 | Soluble |
| 206 | W | E | 0.0000 | Buried |
| 207 | K | E | -3.1223 | Soluble |
| 208 | S | E | -2.2750 | Soluble |
| 209 | H | E | -2.4626 | Soluble |
| 210 | R | E | -2.6934 | Soluble |
| 211 | S | E | -1.8663 | Soluble |
| 212 | Y | E | 0.0000 | Buried |
| 213 | S | E | 0.0000 | Buried |
| 214 | C | E | 0.0000 | Buried |
| 215 | Q | E | -0.8161 | Soluble |
| 216 | V | E | 0.0000 | Buried |
| 217 | T | E | -0.8098 | Soluble |
| 218 | H | E | -1.1595 | Soluble |
| 219 | E | E | -2.2038 | Soluble |
| 220 | G | E | -1.5151 | Soluble |
| 221 | S | E | -1.1647 | Soluble |
| 222 | T | E | -0.9327 | Soluble |
| 223 | V | E | -0.7880 | Soluble |
| 224 | E | E | -2.0379 | Soluble |
| 225 | K | E | -1.4902 | Soluble |
| 226 | T | E | -1.1668 | Soluble |
| 227 | V | E | 0.0000 | Buried |
| 228 | A | E | -1.4633 | Soluble |
| 229 | P | E | -1.3080 | Soluble |
| 230 | T | E | -1.2135 | Soluble |
| 231 | E | E | -1.8410 | Soluble |
| 232 | C | E | -0.8467 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.5773 | 4.4914 | CSV PDB |
| 4.5 | -0.6117 | 4.4581 | CSV PDB |
| 5.0 | -0.6536 | 4.4131 | CSV PDB |
| 5.5 | -0.6937 | 4.364 | CSV PDB |
| 6.0 | -0.7217 | 4.3182 | CSV PDB |
| 6.5 | -0.7301 | 4.2835 | CSV PDB |
| 7.0 | -0.7181 | 4.2638 | CSV PDB |
| 7.5 | -0.6922 | 4.2554 | CSV PDB |
| 8.0 | -0.6587 | 4.2524 | CSV PDB |
| 8.5 | -0.6205 | 4.2515 | CSV PDB |
| 9.0 | -0.5784 | 4.2512 | CSV PDB |