Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPDIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | E (Heavy), D (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | E | -2.0200 | Soluble |
| 2 | V | E | -1.2002 | Soluble |
| 3 | Q | E | -1.2059 | Soluble |
| 4 | L | E | 0.0000 | Buried |
| 5 | V | E | 0.6830 | Aggregation-prone |
| 6 | E | E | 0.0000 | Buried |
| 7 | S | E | -0.4056 | Soluble |
| 8 | G | E | -0.6353 | Soluble |
| 9 | G | E | -0.2382 | Soluble |
| 11 | G | E | 0.1263 | Aggregation-prone |
| 12 | L | E | -0.1014 | Soluble |
| 13 | V | E | -0.1690 | Soluble |
| 14 | Q | E | -1.4727 | Soluble |
| 15 | P | E | -1.7489 | Soluble |
| 16 | G | E | -1.4792 | Soluble |
| 17 | G | E | 0.0000 | Buried |
| 18 | S | E | -0.8441 | Soluble |
| 19 | L | E | -0.8387 | Soluble |
| 20 | R | E | -1.9904 | Soluble |
| 21 | L | E | 0.0000 | Buried |
| 22 | S | E | -0.3370 | Soluble |
| 23 | C | E | 0.0000 | Buried |
| 24 | A | E | -0.1954 | Soluble |
| 25 | A | E | -0.6651 | Soluble |
| 26 | S | E | -0.8714 | Soluble |
| 27 | G | E | -1.0509 | Soluble |
| 28 | F | E | -1.0385 | Soluble |
| 29 | N | E | -1.7942 | Soluble |
| 30 | I | E | 0.0000 | Buried |
| 35 | K | E | -2.8530 | Soluble |
| 36 | D | E | -2.9303 | Soluble |
| 37 | T | E | 0.0000 | Buried |
| 38 | Y | E | -0.4402 | Soluble |
| 39 | I | E | 0.0000 | Buried |
| 40 | H | E | 0.0000 | Buried |
| 41 | W | E | 0.0000 | Buried |
| 42 | V | E | 0.0000 | Buried |
| 43 | R | E | -0.4346 | Soluble |
| 44 | Q | E | 0.0000 | Buried |
| 45 | A | E | -1.1859 | Soluble |
| 46 | P | E | -0.9502 | Soluble |
| 47 | G | E | -1.4881 | Soluble |
| 48 | K | E | -2.3878 | Soluble |
| 49 | G | E | -1.8045 | Soluble |
| 50 | L | E | 0.0000 | Buried |
| 51 | E | E | -1.4444 | Soluble |
| 52 | W | E | 0.0000 | Buried |
| 53 | V | E | 0.0000 | Buried |
| 54 | A | E | 0.0000 | Buried |
| 55 | R | E | -0.5461 | Soluble |
| 56 | I | E | 0.0000 | Buried |
| 57 | Y | E | -0.4871 | Soluble |
| 58 | P | E | -0.9275 | Soluble |
| 59 | T | E | -1.2423 | Soluble |
| 62 | N | E | -1.1210 | Soluble |
| 63 | G | E | -0.3243 | Soluble |
| 64 | Y | E | 0.4376 | Aggregation-prone |
| 65 | T | E | -0.5102 | Soluble |
| 66 | R | E | -2.1039 | Soluble |
| 67 | Y | E | -1.9716 | Soluble |
| 68 | A | E | -2.0065 | Soluble |
| 69 | D | E | -2.8494 | Soluble |
| 70 | S | E | -1.6527 | Soluble |
| 71 | V | E | 0.0000 | Buried |
| 72 | K | E | -3.0299 | Soluble |
| 74 | G | E | -1.9635 | Soluble |
| 75 | R | E | -1.3930 | Soluble |
| 76 | F | E | 0.0000 | Buried |
| 77 | T | E | -0.9933 | Soluble |
| 78 | I | E | 0.0000 | Buried |
| 79 | S | E | -0.3548 | Soluble |
| 80 | A | E | -0.5392 | Soluble |
| 81 | D | E | -1.1286 | Soluble |
| 82 | T | E | -1.5325 | Soluble |
| 83 | S | E | -1.5081 | Soluble |
| 84 | K | E | -2.1131 | Soluble |
| 85 | N | E | -1.5964 | Soluble |
| 86 | T | E | -0.7876 | Soluble |
| 87 | A | E | 0.0000 | Buried |
| 88 | Y | E | -0.5360 | Soluble |
| 89 | L | E | 0.0000 | Buried |
| 90 | Q | E | -1.2216 | Soluble |
| 91 | M | E | 0.0000 | Buried |
| 92 | N | E | -1.2013 | Soluble |
| 93 | S | E | -1.2455 | Soluble |
| 94 | L | E | 0.0000 | Buried |
| 95 | R | E | -2.7701 | Soluble |
| 96 | A | E | -1.8663 | Soluble |
| 97 | E | E | -2.3718 | Soluble |
| 98 | D | E | 0.0000 | Buried |
| 99 | T | E | -0.7800 | Soluble |
| 100 | A | E | 0.0000 | Buried |
| 101 | V | E | 0.0310 | Aggregation-prone |
| 102 | Y | E | 0.0000 | Buried |
| 103 | Y | E | 0.0000 | Buried |
| 104 | C | E | 0.0000 | Buried |
| 105 | S | E | 0.0000 | Buried |
| 106 | R | E | 0.0000 | Buried |
| 107 | W | E | 0.0000 | Buried |
| 108 | G | E | -0.9633 | Soluble |
| 109 | G | E | -1.3442 | Soluble |
| 110 | D | E | -2.1841 | Soluble |
| 111 | G | E | -1.1655 | Soluble |
| 112 | F | E | -0.3285 | Soluble |
| 113 | Y | E | 0.1597 | Aggregation-prone |
| 114 | A | E | 0.0000 | Buried |
| 115 | M | E | 0.0000 | Buried |
| 116 | D | E | 0.0000 | Buried |
| 117 | Y | E | -0.2574 | Soluble |
| 118 | W | E | 0.0000 | Buried |
| 119 | G | E | -0.4728 | Soluble |
| 120 | Q | E | -1.1198 | Soluble |
| 121 | G | E | -0.4651 | Soluble |
| 122 | T | E | 0.0943 | Aggregation-prone |
| 123 | L | E | 0.5310 | Aggregation-prone |
| 124 | V | E | 0.0000 | Buried |
| 125 | T | E | -0.1677 | Soluble |
| 126 | V | E | 0.0000 | Buried |
| 127 | S | E | -0.9661 | Soluble |
| 128 | S | E | -0.5086 | Soluble |
| 129 | A | E | -0.4596 | Soluble |
| 130 | S | E | -0.5715 | Soluble |
| 131 | T | E | -1.3534 | Soluble |
| 132 | K | E | -2.2028 | Soluble |
| 133 | G | E | 0.0000 | Buried |
| 134 | P | E | 0.0000 | Buried |
| 135 | S | E | -0.9803 | Soluble |
| 136 | V | E | 0.0000 | Buried |
| 137 | F | E | 0.0000 | Buried |
| 138 | P | E | -0.9398 | Soluble |
| 139 | L | E | 0.0000 | Buried |
| 140 | A | E | -0.5342 | Soluble |
| 141 | P | E | -0.7820 | Soluble |
| 142 | S | E | -1.0948 | Soluble |
| 143 | S | E | -1.2426 | Soluble |
| 144 | K | E | -1.9986 | Soluble |
| 145 | S | E | -1.3840 | Soluble |
| 146 | T | E | -1.0128 | Soluble |
| 147 | S | E | -0.7472 | Soluble |
| 148 | G | E | -0.7943 | Soluble |
| 149 | G | E | -0.8628 | Soluble |
| 150 | T | E | -0.5439 | Soluble |
| 151 | A | E | -0.5234 | Soluble |
| 152 | A | E | 0.0000 | Buried |
| 153 | L | E | 0.0000 | Buried |
| 154 | G | E | 0.0000 | Buried |
| 155 | C | E | 0.0000 | Buried |
| 156 | L | E | 0.0000 | Buried |
| 157 | V | E | 0.0000 | Buried |
| 158 | K | E | 0.0000 | Buried |
| 159 | D | E | -0.6072 | Soluble |
| 160 | Y | E | 0.0000 | Buried |
| 161 | F | E | -0.5699 | Soluble |
| 162 | P | E | 0.0000 | Buried |
| 163 | E | E | -0.9271 | Soluble |
| 164 | P | E | -0.8225 | Soluble |
| 165 | V | E | 0.0528 | Aggregation-prone |
| 166 | T | E | -0.4706 | Soluble |
| 167 | V | E | 0.2013 | Aggregation-prone |
| 168 | S | E | -0.0580 | Soluble |
| 169 | W | E | 0.0000 | Buried |
| 170 | N | E | -1.2381 | Soluble |
| 171 | S | E | -0.8347 | Soluble |
| 172 | G | E | -0.7338 | Soluble |
| 173 | A | E | -0.3990 | Soluble |
| 174 | L | E | 0.0986 | Aggregation-prone |
| 175 | T | E | 0.0773 | Aggregation-prone |
| 176 | S | E | -0.0315 | Soluble |
| 177 | G | E | -0.1020 | Soluble |
| 178 | V | E | 1.1204 | Aggregation-prone |
| 179 | H | E | 0.0788 | Aggregation-prone |
| 180 | T | E | 0.0276 | Aggregation-prone |
| 181 | F | E | 0.0000 | Buried |
| 182 | P | E | -0.1625 | Soluble |
| 183 | A | E | 0.1445 | Aggregation-prone |
| 184 | V | E | 0.5409 | Aggregation-prone |
| 185 | L | E | 1.3970 | Aggregation-prone |
| 186 | Q | E | 0.3017 | Aggregation-prone |
| 187 | S | E | -0.1289 | Soluble |
| 188 | S | E | -0.3703 | Soluble |
| 189 | G | E | 0.2090 | Aggregation-prone |
| 190 | L | E | 0.0000 | Buried |
| 191 | Y | E | 0.4885 | Aggregation-prone |
| 192 | S | E | 0.2924 | Aggregation-prone |
| 193 | L | E | -0.0943 | Soluble |
| 194 | S | E | 0.0000 | Buried |
| 195 | S | E | 0.0000 | Buried |
| 196 | V | E | 0.0000 | Buried |
| 197 | V | E | 0.0000 | Buried |
| 198 | T | E | 0.0254 | Aggregation-prone |
| 199 | V | E | 0.0000 | Buried |
| 200 | P | E | -0.4206 | Soluble |
| 201 | S | E | -0.5159 | Soluble |
| 202 | S | E | -0.3785 | Soluble |
| 203 | S | E | -0.2687 | Soluble |
| 204 | L | E | -0.1993 | Soluble |
| 205 | G | E | -0.5468 | Soluble |
| 206 | T | E | -0.3410 | Soluble |
| 207 | Q | E | -0.4356 | Soluble |
| 208 | T | E | -0.3667 | Soluble |
| 209 | Y | E | 0.0000 | Buried |
| 210 | I | E | -0.3975 | Soluble |
| 211 | C | E | 0.0000 | Buried |
| 212 | N | E | -1.5028 | Soluble |
| 213 | V | E | 0.0000 | Buried |
| 214 | N | E | -1.8644 | Soluble |
| 215 | H | E | 0.0000 | Buried |
| 216 | K | E | -2.5641 | Soluble |
| 217 | P | E | -1.7822 | Soluble |
| 218 | S | E | -2.0589 | Soluble |
| 219 | N | E | -2.6845 | Soluble |
| 220 | T | E | -2.2230 | Soluble |
| 221 | K | E | -2.4118 | Soluble |
| 222 | V | E | -1.8225 | Soluble |
| 223 | D | E | -2.5960 | Soluble |
| 224 | K | E | -2.2605 | Soluble |
| 225 | K | E | -1.1421 | Soluble |
| 226 | V | E | 0.0000 | Buried |
| 227 | E | E | -0.7129 | Soluble |
| 228 | P | E | -0.5321 | Soluble |
| 1 | D | D | -2.1338 | Soluble |
| 2 | I | D | -1.6074 | Soluble |
| 3 | Q | D | -2.0657 | Soluble |
| 4 | M | D | 0.0000 | Buried |
| 5 | T | D | -1.2967 | Soluble |
| 6 | Q | D | 0.0000 | Buried |
| 7 | S | D | -0.8084 | Soluble |
| 8 | P | D | -0.6047 | Soluble |
| 9 | S | D | -0.6740 | Soluble |
| 10 | S | D | -0.3141 | Soluble |
| 11 | L | D | -0.1176 | Soluble |
| 12 | S | D | -0.6638 | Soluble |
| 13 | A | D | -1.0056 | Soluble |
| 14 | S | D | -0.9081 | Soluble |
| 15 | V | D | -0.2932 | Soluble |
| 16 | G | D | -1.0553 | Soluble |
| 17 | D | D | -2.0767 | Soluble |
| 18 | R | D | -2.5174 | Soluble |
| 19 | V | D | 0.0000 | Buried |
| 20 | T | D | -0.6590 | Soluble |
| 21 | I | D | 0.0000 | Buried |
| 22 | T | D | -0.7231 | Soluble |
| 23 | C | D | 0.0000 | Buried |
| 24 | R | D | -2.1112 | Soluble |
| 25 | A | D | 0.0000 | Buried |
| 26 | S | D | -2.0386 | Soluble |
| 27 | Q | D | -2.8490 | Soluble |
| 28 | D | D | -2.6285 | Soluble |
| 29 | V | D | 0.0000 | Buried |
| 36 | N | D | -1.8396 | Soluble |
| 37 | T | D | -0.9742 | Soluble |
| 38 | A | D | 0.0605 | Aggregation-prone |
| 39 | V | D | 0.0000 | Buried |
| 40 | A | D | 0.0000 | Buried |
| 41 | W | D | 0.0000 | Buried |
| 42 | Y | D | 0.0000 | Buried |
| 43 | Q | D | -0.8864 | Soluble |
| 44 | Q | D | -1.2650 | Soluble |
| 45 | K | D | -1.5377 | Soluble |
| 46 | P | D | -1.5406 | Soluble |
| 47 | G | D | -1.6437 | Soluble |
| 48 | K | D | -2.4483 | Soluble |
| 49 | A | D | -1.5027 | Soluble |
| 50 | P | D | 0.0000 | Buried |
| 51 | K | D | -1.1825 | Soluble |
| 52 | L | D | 0.0000 | Buried |
| 53 | L | D | 0.0000 | Buried |
| 54 | I | D | 0.0000 | Buried |
| 55 | Y | D | 1.2256 | Aggregation-prone |
| 56 | S | D | 0.6582 | Aggregation-prone |
| 57 | A | D | 0.0000 | Buried |
| 65 | S | D | 0.5350 | Aggregation-prone |
| 66 | F | D | 2.1186 | Aggregation-prone |
| 67 | L | D | 1.3254 | Aggregation-prone |
| 68 | Y | D | 0.8399 | Aggregation-prone |
| 69 | S | D | 0.2066 | Aggregation-prone |
| 70 | G | D | -0.2532 | Soluble |
| 71 | V | D | 0.2232 | Aggregation-prone |
| 72 | P | D | -0.2436 | Soluble |
| 74 | S | D | -0.4170 | Soluble |
| 75 | R | D | -0.8444 | Soluble |
| 76 | F | D | -0.1429 | Soluble |
| 77 | S | D | -0.2196 | Soluble |
| 78 | G | D | -0.1170 | Soluble |
| 79 | S | D | -0.8655 | Soluble |
| 80 | R | D | -1.8663 | Soluble |
| 83 | S | D | -1.4569 | Soluble |
| 84 | G | D | -1.4251 | Soluble |
| 85 | T | D | -1.9071 | Soluble |
| 86 | D | D | -1.6095 | Soluble |
| 87 | F | D | 0.0000 | Buried |
| 88 | T | D | -0.8313 | Soluble |
| 89 | L | D | 0.0000 | Buried |
| 90 | T | D | -0.7915 | Soluble |
| 91 | I | D | 0.0000 | Buried |
| 92 | S | D | -1.5733 | Soluble |
| 93 | S | D | -1.3409 | Soluble |
| 94 | L | D | 0.0000 | Buried |
| 95 | Q | D | -1.0811 | Soluble |
| 96 | P | D | -1.2545 | Soluble |
| 97 | E | D | -1.9960 | Soluble |
| 98 | D | D | -1.1605 | Soluble |
| 99 | F | D | -0.7492 | Soluble |
| 100 | A | D | 0.0000 | Buried |
| 101 | T | D | -0.3985 | Soluble |
| 102 | Y | D | 0.0000 | Buried |
| 103 | Y | D | 0.0000 | Buried |
| 104 | C | D | 0.0000 | Buried |
| 105 | Q | D | 0.0000 | Buried |
| 106 | Q | D | 0.0000 | Buried |
| 107 | H | D | 0.3665 | Aggregation-prone |
| 108 | Y | D | 0.5186 | Aggregation-prone |
| 109 | T | D | 0.1812 | Aggregation-prone |
| 114 | T | D | -0.4203 | Soluble |
| 115 | P | D | -0.8256 | Soluble |
| 116 | P | D | 0.0000 | Buried |
| 117 | T | D | -0.6218 | Soluble |
| 118 | F | D | -0.5690 | Soluble |
| 119 | G | D | 0.0000 | Buried |
| 120 | Q | D | -1.8175 | Soluble |
| 121 | G | D | -1.2125 | Soluble |
| 122 | T | D | 0.0000 | Buried |
| 123 | K | D | -0.4298 | Soluble |
| 124 | V | D | 0.0000 | Buried |
| 125 | E | D | 0.0000 | Buried |
| 126 | I | D | 0.0000 | Buried |
| 127 | K | D | -1.6243 | Soluble |
| 128 | R | D | -1.9880 | Soluble |
| 129 | T | D | -0.5781 | Soluble |
| 130 | V | D | 0.1644 | Aggregation-prone |
| 131 | A | D | -0.0471 | Soluble |
| 132 | A | D | -0.0595 | Soluble |
| 133 | P | D | 0.0000 | Buried |
| 134 | S | D | -0.1850 | Soluble |
| 135 | V | D | -0.1286 | Soluble |
| 136 | F | D | 0.0000 | Buried |
| 137 | I | D | 0.0000 | Buried |
| 138 | F | D | 0.0000 | Buried |
| 139 | P | D | 0.0000 | Buried |
| 140 | P | D | 0.0000 | Buried |
| 141 | S | D | -1.5182 | Soluble |
| 142 | D | D | -3.0775 | Soluble |
| 143 | E | D | -3.0842 | Soluble |
| 144 | Q | D | 0.0000 | Buried |
| 145 | L | D | 0.0000 | Buried |
| 146 | K | D | -2.6705 | Soluble |
| 147 | S | D | -1.2880 | Soluble |
| 148 | G | D | -0.5318 | Soluble |
| 149 | T | D | -0.3448 | Soluble |
| 150 | A | D | 0.0000 | Buried |
| 151 | S | D | -0.0398 | Soluble |
| 152 | V | D | 0.0000 | Buried |
| 153 | V | D | 0.0000 | Buried |
| 154 | C | D | 0.0000 | Buried |
| 155 | L | D | 0.0000 | Buried |
| 156 | L | D | 0.0000 | Buried |
| 157 | N | D | -0.4494 | Soluble |
| 158 | N | D | -1.0207 | Soluble |
| 159 | F | D | 0.0000 | Buried |
| 160 | Y | D | 0.0000 | Buried |
| 161 | P | D | -1.1415 | Soluble |
| 162 | R | D | -1.4432 | Soluble |
| 163 | E | D | -2.3060 | Soluble |
| 164 | A | D | -1.7624 | Soluble |
| 165 | K | D | -1.7316 | Soluble |
| 166 | V | D | 0.1365 | Aggregation-prone |
| 167 | Q | D | -1.0616 | Soluble |
| 168 | W | D | -1.0613 | Soluble |
| 169 | K | D | -2.4460 | Soluble |
| 170 | V | D | 0.0000 | Buried |
| 171 | D | D | -2.5157 | Soluble |
| 172 | N | D | -2.1282 | Soluble |
| 173 | A | D | -0.6703 | Soluble |
| 174 | L | D | 0.6666 | Aggregation-prone |
| 175 | Q | D | -0.3868 | Soluble |
| 176 | S | D | -0.2812 | Soluble |
| 177 | G | D | -0.5662 | Soluble |
| 178 | N | D | -0.6084 | Soluble |
| 179 | S | D | -0.8055 | Soluble |
| 180 | Q | D | -1.0310 | Soluble |
| 181 | E | D | -1.8495 | Soluble |
| 182 | S | D | 0.0000 | Buried |
| 183 | V | D | -0.6878 | Soluble |
| 184 | T | D | 0.0000 | Buried |
| 185 | E | D | -2.0714 | Soluble |
| 186 | Q | D | 0.0000 | Buried |
| 187 | D | D | -2.7612 | Soluble |
| 188 | S | D | -2.5098 | Soluble |
| 189 | K | D | -2.5895 | Soluble |
| 190 | D | D | -2.0210 | Soluble |
| 191 | S | D | 0.0000 | Buried |
| 192 | T | D | 0.0000 | Buried |
| 193 | Y | D | 0.0000 | Buried |
| 194 | S | D | 0.0000 | Buried |
| 195 | L | D | -0.3491 | Soluble |
| 196 | S | D | 0.0000 | Buried |
| 197 | S | D | 0.0000 | Buried |
| 198 | T | D | 0.0000 | Buried |
| 199 | L | D | 0.1185 | Aggregation-prone |
| 200 | T | D | 0.6012 | Aggregation-prone |
| 201 | L | D | 1.2859 | Aggregation-prone |
| 202 | S | D | -0.0392 | Soluble |
| 203 | K | D | 0.0000 | Buried |
| 204 | A | D | -1.8789 | Soluble |
| 205 | D | D | 0.0000 | Buried |
| 206 | Y | D | -2.3132 | Soluble |
| 207 | E | D | -3.1025 | Soluble |
| 208 | K | D | -2.9822 | Soluble |
| 209 | H | D | -2.3855 | Soluble |
| 210 | K | D | -2.1203 | Soluble |
| 211 | V | D | -1.0619 | Soluble |
| 212 | Y | D | -0.6287 | Soluble |
| 213 | A | D | -0.9664 | Soluble |
| 214 | C | D | 0.0000 | Buried |
| 215 | E | D | -0.9697 | Soluble |
| 216 | V | D | 0.0000 | Buried |
| 217 | T | D | -0.6882 | Soluble |
| 218 | H | D | 0.0000 | Buried |
| 219 | Q | D | -1.2481 | Soluble |
| 220 | G | D | -0.5310 | Soluble |
| 221 | L | D | -0.0555 | Soluble |
| 222 | S | D | -0.2102 | Soluble |
| 223 | S | D | -0.2245 | Soluble |
| 224 | P | D | -0.2468 | Soluble |
| 225 | V | D | -0.0416 | Soluble |
| 226 | T | D | -0.1791 | Soluble |
| 227 | K | D | -0.1363 | Soluble |
| 228 | S | D | -0.3655 | Soluble |
| 229 | F | D | -1.0138 | Soluble |
| 230 | N | D | -2.4659 | Soluble |
| 231 | R | D | -3.5105 | Soluble |
| 232 | G | D | -2.5297 | Soluble |
| 233 | E | D | -2.5189 | Soluble |
| 234 | C | D | -1.1136 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6664 | 3.8097 | CSV PDB |
| 4.5 | -0.7102 | 3.8097 | CSV PDB |
| 5.0 | -0.7614 | 3.8097 | CSV PDB |
| 5.5 | -0.81 | 3.8097 | CSV PDB |
| 6.0 | -0.8446 | 3.8097 | CSV PDB |
| 6.5 | -0.8567 | 3.8097 | CSV PDB |
| 7.0 | -0.8474 | 3.8097 | CSV PDB |
| 7.5 | -0.8247 | 3.8097 | CSV PDB |
| 8.0 | -0.7948 | 3.8096 | CSV PDB |
| 8.5 | -0.7592 | 3.8095 | CSV PDB |
| 9.0 | -0.7171 | 3.809 | CSV PDB |