Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGYDFDNYGMNWVRQAPGKGLEWVGWINTYTGEPTYAADFKRRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCAKYPHYYGSSHWYFDVWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHDIQMTQSPSSLSASVGDRVTITCSASQDISNYLNWYQQKPGKAPKVLIYFTDDLHSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYSTVPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.1001 | Soluble |
| 2 | V | A | -1.3991 | Soluble |
| 3 | Q | A | -1.2616 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 1.0815 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.3779 | Soluble |
| 8 | G | A | -0.8874 | Soluble |
| 9 | G | A | -0.4196 | Soluble |
| 11 | G | A | -0.2256 | Soluble |
| 12 | L | A | 0.0545 | Aggregation-prone |
| 13 | V | A | -0.6084 | Soluble |
| 14 | Q | A | -1.4736 | Soluble |
| 15 | P | A | -1.4337 | Soluble |
| 16 | G | A | -1.4125 | Soluble |
| 17 | G | A | -1.1025 | Soluble |
| 18 | S | A | -1.2006 | Soluble |
| 19 | L | A | -1.2506 | Soluble |
| 20 | R | A | -2.2125 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.3631 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.0183 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.2081 | Soluble |
| 27 | G | A | -1.5677 | Soluble |
| 28 | Y | A | -1.5746 | Soluble |
| 29 | D | A | -2.4320 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | D | A | -1.7001 | Soluble |
| 36 | N | A | -2.0148 | Soluble |
| 37 | Y | A | -1.0195 | Soluble |
| 38 | G | A | -0.4570 | Soluble |
| 39 | M | A | 0.0000 | Buried |
| 40 | N | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.7597 | Soluble |
| 45 | A | A | 0.0000 | Buried |
| 46 | P | A | -0.9539 | Soluble |
| 47 | G | A | -1.4631 | Soluble |
| 48 | K | A | -2.3217 | Soluble |
| 49 | G | A | -1.5112 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.9190 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | W | A | -0.1226 | Soluble |
| 56 | I | A | 0.0000 | Buried |
| 57 | N | A | -0.9533 | Soluble |
| 58 | T | A | 0.0000 | Buried |
| 59 | Y | A | 0.1868 | Aggregation-prone |
| 62 | T | A | -0.2992 | Soluble |
| 63 | G | A | -1.0305 | Soluble |
| 64 | E | A | -1.8776 | Soluble |
| 65 | P | A | -1.0822 | Soluble |
| 66 | T | A | -0.4495 | Soluble |
| 67 | Y | A | -0.5896 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | A | A | -1.5643 | Soluble |
| 70 | D | A | -2.5563 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | K | A | -2.9271 | Soluble |
| 74 | R | A | -3.1611 | Soluble |
| 75 | R | A | -2.2990 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -1.2193 | Soluble |
| 78 | F | A | 0.0000 | Buried |
| 79 | S | A | -0.5209 | Soluble |
| 80 | L | A | -0.5198 | Soluble |
| 81 | D | A | -1.0764 | Soluble |
| 82 | T | A | -1.1894 | Soluble |
| 83 | S | A | -1.3249 | Soluble |
| 84 | K | A | -2.0032 | Soluble |
| 85 | S | A | -1.5303 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | -0.5391 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.5328 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -1.7792 | Soluble |
| 93 | S | A | -1.4848 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.3597 | Soluble |
| 96 | A | A | -1.6715 | Soluble |
| 97 | E | A | -2.2199 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.6724 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2374 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | K | A | 0.0000 | Buried |
| 107 | Y | A | 0.0000 | Buried |
| 108 | P | A | 0.0000 | Buried |
| 109 | H | A | -0.3066 | Soluble |
| 110 | Y | A | 1.2931 | Aggregation-prone |
| 111 | Y | A | 1.4099 | Aggregation-prone |
| 111A | G | A | 0.2779 | Aggregation-prone |
| 112B | S | A | 0.2711 | Aggregation-prone |
| 112A | S | A | 0.3141 | Aggregation-prone |
| 112 | H | A | 0.5776 | Aggregation-prone |
| 113 | W | A | 0.6608 | Aggregation-prone |
| 114 | Y | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.4963 | Soluble |
| 117 | V | A | -0.2982 | Soluble |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.2672 | Soluble |
| 121 | G | A | -0.5291 | Soluble |
| 122 | T | A | 0.0101 | Aggregation-prone |
| 123 | L | A | 0.1350 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.3137 | Soluble |
| 126 | V | A | -0.8392 | Soluble |
| 127 | S | A | -0.6421 | Soluble |
| 128 | S | A | -0.5854 | Soluble |
| 129 | A | A | -0.3753 | Soluble |
| 130 | S | A | -0.4175 | Soluble |
| 131 | T | A | -0.6303 | Soluble |
| 132 | K | A | -1.2660 | Soluble |
| 133 | G | A | -1.4736 | Soluble |
| 134 | P | A | -0.6641 | Soluble |
| 135 | S | A | -0.3946 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.2142 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.1597 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.5582 | Soluble |
| 143 | G | A | -0.6407 | Soluble |
| 144 | T | A | -0.4939 | Soluble |
| 145 | A | A | -0.2505 | Soluble |
| 146 | A | A | 0.0000 | Buried |
| 147 | L | A | 0.0000 | Buried |
| 148 | G | A | 0.0000 | Buried |
| 149 | C | A | 0.0000 | Buried |
| 150 | L | A | 0.0000 | Buried |
| 151 | V | A | 0.0000 | Buried |
| 152 | K | A | 0.0000 | Buried |
| 153 | D | A | -0.3696 | Soluble |
| 154 | Y | A | 0.0000 | Buried |
| 155 | F | A | -0.2303 | Soluble |
| 156 | P | A | 0.0000 | Buried |
| 157 | E | A | -0.5344 | Soluble |
| 158 | P | A | -0.7198 | Soluble |
| 159 | V | A | -0.8218 | Soluble |
| 160 | T | A | -0.7912 | Soluble |
| 161 | V | A | -0.4892 | Soluble |
| 162 | S | A | -0.4421 | Soluble |
| 163 | W | A | 0.0000 | Buried |
| 164 | N | A | -0.6939 | Soluble |
| 165 | S | A | -0.6236 | Soluble |
| 166 | G | A | -0.5333 | Soluble |
| 167 | A | A | -0.2164 | Soluble |
| 168 | L | A | 0.0198 | Aggregation-prone |
| 169 | T | A | -0.1468 | Soluble |
| 170 | S | A | -0.1845 | Soluble |
| 171 | G | A | -0.1483 | Soluble |
| 172 | V | A | 0.2337 | Aggregation-prone |
| 173 | H | A | -0.2622 | Soluble |
| 174 | T | A | -0.1356 | Soluble |
| 175 | F | A | 0.0000 | Buried |
| 176 | P | A | -0.3182 | Soluble |
| 177 | A | A | 0.1992 | Aggregation-prone |
| 178 | V | A | 0.4617 | Aggregation-prone |
| 179 | L | A | 1.0726 | Aggregation-prone |
| 180 | Q | A | 0.1981 | Aggregation-prone |
| 181 | S | A | -0.1236 | Soluble |
| 182 | S | A | -0.2574 | Soluble |
| 183 | G | A | -0.0019 | Soluble |
| 184 | L | A | 0.1365 | Aggregation-prone |
| 185 | Y | A | 0.4438 | Aggregation-prone |
| 186 | S | A | 0.0000 | Buried |
| 187 | L | A | 0.0000 | Buried |
| 188 | S | A | 0.0000 | Buried |
| 189 | S | A | 0.0000 | Buried |
| 190 | V | A | 0.0000 | Buried |
| 191 | V | A | 0.0000 | Buried |
| 192 | T | A | -0.1083 | Soluble |
| 193 | V | A | 0.0000 | Buried |
| 194 | P | A | -0.5770 | Soluble |
| 195 | S | A | -0.5605 | Soluble |
| 196 | S | A | -0.6077 | Soluble |
| 197 | S | A | -0.5966 | Soluble |
| 198 | L | A | -0.8295 | Soluble |
| 199 | G | A | -0.9855 | Soluble |
| 200 | T | A | -0.6927 | Soluble |
| 201 | Q | A | -1.1802 | Soluble |
| 202 | T | A | -1.0592 | Soluble |
| 203 | Y | A | 0.0000 | Buried |
| 204 | I | A | -1.1943 | Soluble |
| 205 | C | A | 0.0000 | Buried |
| 206 | N | A | -1.5529 | Soluble |
| 207 | V | A | 0.0000 | Buried |
| 208 | N | A | -2.5561 | Soluble |
| 209 | H | A | 0.0000 | Buried |
| 210 | K | A | -2.9113 | Soluble |
| 211 | P | A | -1.6172 | Soluble |
| 212 | S | A | -1.9393 | Soluble |
| 213 | N | A | -2.6697 | Soluble |
| 214 | T | A | -2.2706 | Soluble |
| 215 | K | A | -2.9262 | Soluble |
| 216 | V | A | -1.7761 | Soluble |
| 217 | D | A | -2.4009 | Soluble |
| 218 | K | A | -1.9963 | Soluble |
| 219 | K | A | -2.2384 | Soluble |
| 220 | V | A | 0.0000 | Buried |
| 221 | E | A | -2.7580 | Soluble |
| 222 | P | A | -1.7833 | Soluble |
| 223 | K | A | -2.3635 | Soluble |
| 224 | S | A | -1.6383 | Soluble |
| 225 | C | A | -1.6649 | Soluble |
| 226 | D | A | -2.7569 | Soluble |
| 227 | K | A | -2.9241 | Soluble |
| 228 | T | A | -1.7211 | Soluble |
| 229 | H | A | -1.4000 | Soluble |
| 1 | D | B | -1.9561 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | Q | B | -2.0029 | Soluble |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -0.9194 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.6165 | Soluble |
| 8 | P | B | -0.5115 | Soluble |
| 9 | S | B | -0.8318 | Soluble |
| 10 | S | B | -0.7751 | Soluble |
| 11 | L | B | -0.5046 | Soluble |
| 12 | S | B | -0.8789 | Soluble |
| 13 | A | B | -1.0105 | Soluble |
| 14 | S | B | -0.9690 | Soluble |
| 15 | V | B | -0.2108 | Soluble |
| 16 | G | B | -1.0067 | Soluble |
| 17 | D | B | -2.0993 | Soluble |
| 18 | R | B | -2.4295 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.6530 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.6414 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | S | B | -1.4794 | Soluble |
| 25 | A | B | -1.7141 | Soluble |
| 26 | S | B | -1.9796 | Soluble |
| 27 | Q | B | -2.6661 | Soluble |
| 28 | D | B | -2.7441 | Soluble |
| 29 | I | B | 0.0000 | Buried |
| 36 | S | B | -1.0882 | Soluble |
| 37 | N | B | -0.7474 | Soluble |
| 38 | Y | B | 0.4187 | Aggregation-prone |
| 39 | L | B | 0.0000 | Buried |
| 40 | N | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | -1.2512 | Soluble |
| 45 | K | B | -1.7341 | Soluble |
| 46 | P | B | -1.4557 | Soluble |
| 47 | G | B | -1.6254 | Soluble |
| 48 | K | B | -2.5298 | Soluble |
| 49 | A | B | -1.5638 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.4082 | Soluble |
| 52 | V | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | -0.0726 | Soluble |
| 56 | F | B | 0.2529 | Aggregation-prone |
| 57 | T | B | 0.0000 | Buried |
| 65 | D | B | -2.1228 | Soluble |
| 66 | D | B | -1.6016 | Soluble |
| 67 | L | B | -0.7029 | Soluble |
| 68 | H | B | -0.8708 | Soluble |
| 69 | S | B | -0.5938 | Soluble |
| 70 | G | B | -0.5963 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | P | B | -0.4154 | Soluble |
| 74 | S | B | -0.4600 | Soluble |
| 75 | R | B | -0.7355 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.9227 | Soluble |
| 78 | G | B | 0.0000 | Buried |
| 79 | S | B | -1.3109 | Soluble |
| 80 | G | B | -1.4692 | Soluble |
| 83 | S | B | -1.2565 | Soluble |
| 84 | G | B | -1.8023 | Soluble |
| 85 | T | B | -2.1250 | Soluble |
| 86 | D | B | -2.5060 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.8805 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.5912 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.3981 | Soluble |
| 93 | S | B | -1.2632 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -0.9620 | Soluble |
| 96 | P | B | -1.4823 | Soluble |
| 97 | E | B | -1.6010 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | -0.8193 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | Y | B | 0.0000 | Buried |
| 108 | S | B | -0.0466 | Soluble |
| 109 | T | B | 0.3750 | Aggregation-prone |
| 114 | V | B | 1.0641 | Aggregation-prone |
| 115 | P | B | 0.2301 | Aggregation-prone |
| 116 | W | B | 0.0000 | Buried |
| 117 | T | B | -0.5355 | Soluble |
| 118 | F | B | -0.4224 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.6035 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.4548 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -1.0877 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.1789 | Soluble |
| 128 | R | B | -0.6819 | Soluble |
| 129 | T | B | 0.2467 | Aggregation-prone |
| 130 | V | B | 1.2065 | Aggregation-prone |
| 131 | A | B | 0.4350 | Aggregation-prone |
| 132 | A | B | 0.0019 | Aggregation-prone |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1749 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.1044 | Aggregation-prone |
| 137 | I | B | 0.0578 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.4332 | Soluble |
| 140 | P | B | -0.7522 | Soluble |
| 141 | S | B | -1.6662 | Soluble |
| 142 | D | B | -2.8817 | Soluble |
| 143 | E | B | -2.5521 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -1.8910 | Soluble |
| 146 | K | B | -2.6223 | Soluble |
| 147 | S | B | -1.6157 | Soluble |
| 148 | G | B | -1.1410 | Soluble |
| 149 | T | B | -0.7616 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.9360 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.3257 | Soluble |
| 162 | R | B | -2.6581 | Soluble |
| 163 | E | B | -2.9493 | Soluble |
| 164 | A | B | -2.2337 | Soluble |
| 165 | K | B | -2.4568 | Soluble |
| 166 | V | B | -1.2135 | Soluble |
| 167 | Q | B | -0.7712 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.6086 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.8411 | Soluble |
| 172 | N | B | -1.5527 | Soluble |
| 173 | A | B | -0.3088 | Soluble |
| 174 | L | B | 0.5168 | Aggregation-prone |
| 175 | Q | B | -0.1627 | Soluble |
| 176 | S | B | -0.4446 | Soluble |
| 177 | G | B | -0.8717 | Soluble |
| 178 | N | B | -0.7802 | Soluble |
| 179 | S | B | -1.1163 | Soluble |
| 180 | Q | B | -1.3532 | Soluble |
| 181 | E | B | -1.8823 | Soluble |
| 182 | S | B | -0.9141 | Soluble |
| 183 | V | B | -0.7112 | Soluble |
| 184 | T | B | 0.0000 | Buried |
| 185 | E | B | -2.1226 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.0190 | Soluble |
| 188 | S | B | -2.1680 | Soluble |
| 189 | K | B | -2.5856 | Soluble |
| 190 | D | B | -2.0283 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.6307 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.3945 | Soluble |
| 201 | L | B | -0.6213 | Soluble |
| 202 | S | B | -0.9304 | Soluble |
| 203 | K | B | -1.8663 | Soluble |
| 204 | A | B | -1.7591 | Soluble |
| 205 | D | B | -2.4164 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.6767 | Soluble |
| 208 | K | B | -3.6469 | Soluble |
| 209 | H | B | -3.0770 | Soluble |
| 210 | K | B | -2.8878 | Soluble |
| 211 | V | B | -1.1821 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.8661 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.2798 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.5794 | Soluble |
| 220 | G | B | -0.2752 | Soluble |
| 221 | L | B | -0.1516 | Soluble |
| 222 | S | B | -0.4682 | Soluble |
| 223 | S | B | -0.4166 | Soluble |
| 224 | P | B | -0.5322 | Soluble |
| 225 | V | B | 0.0342 | Aggregation-prone |
| 226 | T | B | -0.5149 | Soluble |
| 227 | K | B | -0.7688 | Soluble |
| 228 | S | B | -0.5228 | Soluble |
| 229 | F | B | -0.5496 | Soluble |
| 230 | N | B | -1.1735 | Soluble |
| 231 | R | B | -2.0827 | Soluble |
| 232 | G | B | -1.9461 | Soluble |
| 233 | E | B | -1.9222 | Soluble |
| 234 | C | B | -0.9574 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7052 | 2.0925 | CSV PDB |
| 4.5 | -0.758 | 1.9447 | CSV PDB |
| 5.0 | -0.819 | 1.7593 | CSV PDB |
| 5.5 | -0.8772 | 1.5587 | CSV PDB |
| 6.0 | -0.9205 | 1.3894 | CSV PDB |
| 6.5 | -0.9405 | 1.3913 | CSV PDB |
| 7.0 | -0.9385 | 1.3886 | CSV PDB |
| 7.5 | -0.9227 | 1.3809 | CSV PDB |
| 8.0 | -0.8989 | 1.3707 | CSV PDB |
| 8.5 | -0.8676 | 1.4483 | CSV PDB |
| 9.0 | -0.8271 | 1.6041 | CSV PDB |