Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTLYLQMNSLRAEDTAVYYCSRWGGDGFYAMDVWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLESGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | B | -2.0672 | Soluble |
| 2 | V | B | -1.3293 | Soluble |
| 3 | Q | B | -1.3337 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | 0.8430 | Aggregation-prone |
| 6 | E | B | 0.0000 | Buried |
| 7 | S | B | -0.3837 | Soluble |
| 8 | G | B | -0.8269 | Soluble |
| 9 | G | B | -0.3943 | Soluble |
| 11 | G | B | -0.1527 | Soluble |
| 12 | L | B | 0.0786 | Aggregation-prone |
| 13 | V | B | -0.6239 | Soluble |
| 14 | Q | B | -1.6829 | Soluble |
| 15 | P | B | -1.9241 | Soluble |
| 16 | G | B | -1.6075 | Soluble |
| 17 | G | B | -1.2037 | Soluble |
| 18 | S | B | -1.0516 | Soluble |
| 19 | L | B | -0.8693 | Soluble |
| 20 | R | B | -1.6383 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.2467 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | A | B | -0.0971 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.9910 | Soluble |
| 27 | G | B | -1.3386 | Soluble |
| 28 | F | B | -1.3898 | Soluble |
| 29 | N | B | -2.0605 | Soluble |
| 30 | I | B | 0.0000 | Buried |
| 35 | K | B | -2.3748 | Soluble |
| 36 | D | B | -2.6667 | Soluble |
| 37 | T | B | 0.0000 | Buried |
| 38 | Y | B | -0.1467 | Soluble |
| 39 | I | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -0.9101 | Soluble |
| 45 | A | B | -1.2473 | Soluble |
| 46 | P | B | -0.9654 | Soluble |
| 47 | G | B | -1.4816 | Soluble |
| 48 | K | B | -2.4623 | Soluble |
| 49 | G | B | -1.7853 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -1.4180 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | V | B | 0.0000 | Buried |
| 54 | A | B | 0.0000 | Buried |
| 55 | R | B | -0.5780 | Soluble |
| 56 | I | B | 0.0000 | Buried |
| 57 | Y | B | -0.3378 | Soluble |
| 58 | P | B | 0.0000 | Buried |
| 59 | T | B | -1.1224 | Soluble |
| 62 | N | B | -0.9941 | Soluble |
| 63 | G | B | -0.3427 | Soluble |
| 64 | Y | B | 0.4850 | Aggregation-prone |
| 65 | T | B | -0.4536 | Soluble |
| 66 | R | B | -2.0129 | Soluble |
| 67 | Y | B | -1.9184 | Soluble |
| 68 | A | B | -1.9120 | Soluble |
| 69 | D | B | -2.6379 | Soluble |
| 70 | S | B | -1.7607 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | K | B | -2.8730 | Soluble |
| 74 | G | B | -1.7921 | Soluble |
| 75 | R | B | -1.3731 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | T | B | -1.0295 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | S | B | -0.0622 | Soluble |
| 80 | A | B | -0.7065 | Soluble |
| 81 | D | B | -1.3713 | Soluble |
| 82 | T | B | -1.5198 | Soluble |
| 83 | S | B | -1.5742 | Soluble |
| 84 | K | B | -2.1300 | Soluble |
| 85 | N | B | -1.7607 | Soluble |
| 86 | T | B | -0.8731 | Soluble |
| 87 | L | B | 0.0000 | Buried |
| 88 | Y | B | -0.3363 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | Q | B | -0.9379 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | N | B | -1.3797 | Soluble |
| 93 | S | B | -1.4238 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -2.8918 | Soluble |
| 96 | A | B | -1.9945 | Soluble |
| 97 | E | B | -2.4623 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.7942 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.2577 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | S | B | 0.0000 | Buried |
| 106 | R | B | -0.3828 | Soluble |
| 107 | W | B | 0.0000 | Buried |
| 108 | G | B | -0.7616 | Soluble |
| 109 | G | B | -1.3688 | Soluble |
| 110 | D | B | -2.1670 | Soluble |
| 111 | G | B | -1.1045 | Soluble |
| 112 | F | B | -0.0168 | Soluble |
| 113 | Y | B | 0.2923 | Aggregation-prone |
| 114 | A | B | 0.0000 | Buried |
| 115 | M | B | 0.0000 | Buried |
| 116 | D | B | -0.5128 | Soluble |
| 117 | V | B | 0.0000 | Buried |
| 118 | W | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.2964 | Soluble |
| 121 | G | B | -0.5277 | Soluble |
| 122 | T | B | -0.0016 | Soluble |
| 123 | L | B | 0.1995 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | -0.4635 | Soluble |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -1.0161 | Soluble |
| 128 | S | B | -0.6921 | Soluble |
| 129 | A | B | -0.5218 | Soluble |
| 130 | S | B | -0.6974 | Soluble |
| 131 | T | B | -1.0043 | Soluble |
| 132 | K | B | -1.7925 | Soluble |
| 133 | G | B | -1.6404 | Soluble |
| 134 | P | B | -0.8413 | Soluble |
| 135 | S | B | -0.5454 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -0.7899 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | 0.0000 | Buried |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -0.9861 | Soluble |
| 143 | S | B | -1.2483 | Soluble |
| 144 | K | B | -1.7091 | Soluble |
| 145 | S | B | -1.1429 | Soluble |
| 146 | T | B | -0.8581 | Soluble |
| 147 | S | B | -0.6865 | Soluble |
| 148 | G | B | -0.9324 | Soluble |
| 149 | G | B | -0.8824 | Soluble |
| 150 | T | B | -0.5705 | Soluble |
| 151 | A | B | -0.3477 | Soluble |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.8733 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.6243 | Soluble |
| 164 | P | B | -0.6219 | Soluble |
| 165 | V | B | -0.5955 | Soluble |
| 166 | T | B | -0.5168 | Soluble |
| 167 | V | B | -0.4004 | Soluble |
| 168 | S | B | -0.4479 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.9072 | Soluble |
| 171 | S | B | -0.7558 | Soluble |
| 172 | G | B | -0.6225 | Soluble |
| 173 | A | B | -0.2807 | Soluble |
| 174 | L | B | -0.0217 | Soluble |
| 175 | T | B | -0.1786 | Soluble |
| 176 | S | B | -0.1624 | Soluble |
| 177 | G | B | -0.2891 | Soluble |
| 178 | V | B | 0.1803 | Aggregation-prone |
| 179 | H | B | -0.2798 | Soluble |
| 180 | T | B | -0.1387 | Soluble |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.2596 | Soluble |
| 183 | A | B | 0.2481 | Aggregation-prone |
| 184 | V | B | 0.3836 | Aggregation-prone |
| 185 | L | B | 0.9476 | Aggregation-prone |
| 186 | Q | B | 0.1373 | Aggregation-prone |
| 187 | S | B | -0.2304 | Soluble |
| 188 | S | B | -0.2865 | Soluble |
| 189 | G | B | -0.0261 | Soluble |
| 190 | L | B | -0.1577 | Soluble |
| 191 | Y | B | 0.2128 | Aggregation-prone |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1219 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.6185 | Soluble |
| 201 | S | B | -0.6221 | Soluble |
| 202 | S | B | -0.6392 | Soluble |
| 203 | S | B | 0.0000 | Buried |
| 204 | L | B | -0.6573 | Soluble |
| 205 | G | B | -0.9460 | Soluble |
| 206 | T | B | -0.6770 | Soluble |
| 207 | Q | B | -1.1021 | Soluble |
| 208 | T | B | -1.0658 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -1.3688 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.5979 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -1.7889 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.2282 | Soluble |
| 217 | P | B | -1.4655 | Soluble |
| 218 | S | B | -1.7899 | Soluble |
| 219 | N | B | -2.3868 | Soluble |
| 220 | T | B | -2.1639 | Soluble |
| 221 | K | B | -2.5918 | Soluble |
| 222 | V | B | -1.7984 | Soluble |
| 223 | D | B | -2.6265 | Soluble |
| 224 | K | B | -2.0457 | Soluble |
| 225 | K | B | -2.4000 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -1.7069 | Soluble |
| 228 | P | B | -0.9248 | Soluble |
| 229 | K | B | -1.2460 | Soluble |
| 230 | S | B | -1.0535 | Soluble |
| 231 | C | B | -1.1884 | Soluble |
| 1 | D | A | -2.2678 | Soluble |
| 2 | I | A | 0.0000 | Buried |
| 3 | Q | A | -2.2968 | Soluble |
| 4 | M | A | 0.0000 | Buried |
| 5 | T | A | -1.3894 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.7894 | Soluble |
| 8 | P | A | -0.5531 | Soluble |
| 9 | S | A | -0.8939 | Soluble |
| 10 | S | A | -0.7849 | Soluble |
| 11 | L | A | -0.6048 | Soluble |
| 12 | S | A | -0.7534 | Soluble |
| 13 | A | A | 0.0000 | Buried |
| 14 | S | A | -0.9395 | Soluble |
| 15 | V | A | -0.1851 | Soluble |
| 16 | G | A | -0.6739 | Soluble |
| 17 | D | A | -1.6491 | Soluble |
| 18 | R | A | -2.3494 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | T | A | -0.6459 | Soluble |
| 21 | I | A | 0.0000 | Buried |
| 22 | T | A | -0.8400 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.8551 | Soluble |
| 25 | A | A | -2.3763 | Soluble |
| 26 | S | A | -2.2638 | Soluble |
| 27 | Q | A | -3.0652 | Soluble |
| 28 | D | A | -3.0009 | Soluble |
| 29 | V | A | 0.0000 | Buried |
| 36 | N | A | -2.1032 | Soluble |
| 37 | T | A | -1.0476 | Soluble |
| 38 | A | A | -0.0064 | Soluble |
| 39 | V | A | 0.0000 | Buried |
| 40 | A | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | -1.2406 | Soluble |
| 45 | K | A | -1.6675 | Soluble |
| 46 | P | A | -1.4523 | Soluble |
| 47 | G | A | -1.5376 | Soluble |
| 48 | K | A | -2.2244 | Soluble |
| 49 | A | A | -1.5144 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | K | A | -1.3360 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | 0.8745 | Aggregation-prone |
| 56 | S | A | 0.4556 | Aggregation-prone |
| 57 | A | A | 0.0000 | Buried |
| 65 | S | A | 0.5163 | Aggregation-prone |
| 66 | F | A | 1.9624 | Aggregation-prone |
| 67 | L | A | 1.0266 | Aggregation-prone |
| 68 | E | A | 0.1525 | Aggregation-prone |
| 69 | S | A | -0.1693 | Soluble |
| 70 | G | A | -0.5246 | Soluble |
| 71 | V | A | -0.3244 | Soluble |
| 72 | P | A | -0.3675 | Soluble |
| 74 | S | A | -0.4160 | Soluble |
| 75 | R | A | -0.7577 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | 0.0216 | Aggregation-prone |
| 78 | G | A | -0.0811 | Soluble |
| 79 | S | A | -0.8013 | Soluble |
| 80 | R | A | -2.0598 | Soluble |
| 83 | S | A | -1.5407 | Soluble |
| 84 | G | A | -1.9578 | Soluble |
| 85 | T | A | -2.3587 | Soluble |
| 86 | D | A | -2.0874 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.8479 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.6393 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -1.4249 | Soluble |
| 93 | S | A | -1.2002 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | Q | A | -1.2635 | Soluble |
| 96 | P | A | -1.3382 | Soluble |
| 97 | E | A | -1.6898 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | F | A | -0.9681 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | T | A | -0.9555 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | Q | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | H | A | 0.5494 | Aggregation-prone |
| 108 | Y | A | 0.8326 | Aggregation-prone |
| 109 | T | A | 0.2519 | Aggregation-prone |
| 114 | T | A | -0.4275 | Soluble |
| 115 | P | A | -0.8882 | Soluble |
| 116 | P | A | 0.0000 | Buried |
| 117 | T | A | -0.7110 | Soluble |
| 118 | F | A | -0.5800 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.8852 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -1.6160 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | E | A | 0.0000 | Buried |
| 126 | I | A | 0.0000 | Buried |
| 127 | K | A | -1.6179 | Soluble |
| 128 | R | A | -1.0065 | Soluble |
| 129 | T | A | 0.0491 | Aggregation-prone |
| 130 | V | A | 0.7920 | Aggregation-prone |
| 131 | A | A | 0.2231 | Aggregation-prone |
| 132 | A | A | -0.0470 | Soluble |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.2093 | Soluble |
| 135 | V | A | 0.0000 | Buried |
| 136 | F | A | -0.0341 | Soluble |
| 137 | I | A | 0.0000 | Buried |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | 0.0000 | Buried |
| 140 | P | A | 0.0000 | Buried |
| 141 | S | A | -1.3044 | Soluble |
| 142 | D | A | -2.2425 | Soluble |
| 143 | E | A | -2.0416 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.0485 | Soluble |
| 146 | K | A | -2.5218 | Soluble |
| 147 | S | A | -1.6075 | Soluble |
| 148 | G | A | -1.5690 | Soluble |
| 149 | T | A | -1.2228 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -0.8244 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.4942 | Soluble |
| 162 | R | A | -2.3244 | Soluble |
| 163 | E | A | -3.0121 | Soluble |
| 164 | A | A | -2.2634 | Soluble |
| 165 | K | A | -2.2430 | Soluble |
| 166 | V | A | -1.3194 | Soluble |
| 167 | Q | A | -0.6679 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.8043 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -1.6964 | Soluble |
| 172 | N | A | -1.4893 | Soluble |
| 173 | A | A | -0.4862 | Soluble |
| 174 | L | A | 0.2307 | Aggregation-prone |
| 175 | Q | A | -0.5763 | Soluble |
| 176 | S | A | -0.7918 | Soluble |
| 177 | G | A | -1.4060 | Soluble |
| 178 | N | A | -1.8019 | Soluble |
| 179 | S | A | -1.6518 | Soluble |
| 180 | Q | A | -1.7771 | Soluble |
| 181 | E | A | -1.9398 | Soluble |
| 182 | S | A | -0.9186 | Soluble |
| 183 | V | A | -0.5087 | Soluble |
| 184 | T | A | -0.9749 | Soluble |
| 185 | E | A | -2.0926 | Soluble |
| 186 | Q | A | 0.0000 | Buried |
| 187 | D | A | -2.0061 | Soluble |
| 188 | S | A | -2.0871 | Soluble |
| 189 | K | A | -2.3229 | Soluble |
| 190 | D | A | -1.8608 | Soluble |
| 191 | S | A | -1.8191 | Soluble |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.8938 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.7245 | Soluble |
| 201 | L | A | -0.8384 | Soluble |
| 202 | S | A | -1.0790 | Soluble |
| 203 | K | A | -2.1730 | Soluble |
| 204 | A | A | -1.7550 | Soluble |
| 205 | D | A | -2.3724 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -2.9295 | Soluble |
| 208 | K | A | -3.1696 | Soluble |
| 209 | H | A | -2.5330 | Soluble |
| 210 | K | A | -2.2912 | Soluble |
| 211 | V | A | -1.0612 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | -0.8174 | Soluble |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.6934 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.1730 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.6339 | Soluble |
| 220 | G | A | -0.3167 | Soluble |
| 221 | L | A | -0.2952 | Soluble |
| 222 | S | A | -0.5072 | Soluble |
| 223 | S | A | -0.4276 | Soluble |
| 224 | P | A | -0.5669 | Soluble |
| 225 | V | A | 0.0699 | Aggregation-prone |
| 226 | T | A | -0.4303 | Soluble |
| 227 | K | A | -0.7359 | Soluble |
| 228 | S | A | -0.7031 | Soluble |
| 229 | F | A | 0.0000 | Buried |
| 230 | N | A | -1.3198 | Soluble |
| 231 | R | A | -1.9018 | Soluble |
| 232 | G | A | -1.5966 | Soluble |
| 233 | E | A | -1.8977 | Soluble |
| 234 | C | A | -0.5738 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7623 | 3.6562 | CSV PDB |
| 4.5 | -0.8043 | 3.6467 | CSV PDB |
| 5.0 | -0.8532 | 3.6339 | CSV PDB |
| 5.5 | -0.8996 | 3.6201 | CSV PDB |
| 6.0 | -0.9325 | 3.6072 | CSV PDB |
| 6.5 | -0.9428 | 3.5975 | CSV PDB |
| 7.0 | -0.9301 | 3.592 | CSV PDB |
| 7.5 | -0.902 | 3.5897 | CSV PDB |
| 8.0 | -0.8654 | 3.5888 | CSV PDB |
| 8.5 | -0.8225 | 3.5885 | CSV PDB |
| 9.0 | -0.7728 | 3.5884 | CSV PDB |