Calculation Parameters
| Chain Sequence(s) |
VQLVESGGGVVQPGRSLRLSCAASGFTFSVYGMNWVRQAPGKGLEWVAIIWYDGDNQYYADSVKGRFTISRDNSKNTLYLQMNGLRAEDTAVYYCARDLRTGPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTEIVLTQSPDFQSVTPKEKVTITCRASQSIGSSLHWYQQKPDQSPKLLIKYASQSFSGVPSRFSGSGSGTDFTLTINSLEAEDAAAYYCHQSSSLPFTFGPGTKVDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 2 | V | B | 0.6582 | Aggregation-prone |
| 3 | Q | B | -0.5373 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | V | B | 0.1703 | Aggregation-prone |
| 6 | E | B | 0.0000 | Buried |
| 7 | S | B | -0.3730 | Soluble |
| 8 | G | B | -0.6293 | Soluble |
| 9 | G | B | -0.0488 | Soluble |
| 11 | G | B | 0.4741 | Aggregation-prone |
| 12 | V | B | 0.8523 | Aggregation-prone |
| 13 | V | B | 0.0000 | Buried |
| 14 | Q | B | -1.2557 | Soluble |
| 15 | P | B | -1.8851 | Soluble |
| 16 | G | B | -2.2066 | Soluble |
| 17 | R | B | -2.7632 | Soluble |
| 18 | S | B | -2.0314 | Soluble |
| 19 | L | B | -1.4473 | Soluble |
| 20 | R | B | -2.0097 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.3534 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | A | B | -0.3778 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.5883 | Soluble |
| 27 | G | B | -0.2092 | Soluble |
| 28 | F | B | 0.2380 | Aggregation-prone |
| 29 | T | B | 0.3196 | Aggregation-prone |
| 30 | F | B | 0.0000 | Buried |
| 35 | S | B | -0.0834 | Soluble |
| 36 | V | B | 0.7921 | Aggregation-prone |
| 37 | Y | B | 0.4385 | Aggregation-prone |
| 38 | G | B | 0.0000 | Buried |
| 39 | M | B | 0.0000 | Buried |
| 40 | N | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -0.7204 | Soluble |
| 45 | A | B | -1.1049 | Soluble |
| 46 | P | B | -0.8775 | Soluble |
| 47 | G | B | -1.5028 | Soluble |
| 48 | K | B | -2.2391 | Soluble |
| 49 | G | B | -1.3613 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -0.9710 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | V | B | 0.0000 | Buried |
| 54 | A | B | 0.0000 | Buried |
| 55 | I | B | 0.0000 | Buried |
| 56 | I | B | 0.0000 | Buried |
| 57 | W | B | -0.8495 | Soluble |
| 58 | Y | B | -0.4141 | Soluble |
| 59 | D | B | -2.0067 | Soluble |
| 62 | G | B | -2.0525 | Soluble |
| 63 | D | B | -2.7204 | Soluble |
| 64 | N | B | -1.9177 | Soluble |
| 65 | Q | B | -0.8248 | Soluble |
| 66 | Y | B | -0.0821 | Soluble |
| 67 | Y | B | -0.7346 | Soluble |
| 68 | A | B | -1.5418 | Soluble |
| 69 | D | B | -2.6539 | Soluble |
| 70 | S | B | -1.8076 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | K | B | -2.4952 | Soluble |
| 74 | G | B | -1.7986 | Soluble |
| 75 | R | B | -1.4061 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | T | B | -0.7881 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | S | B | -0.7755 | Soluble |
| 80 | R | B | -1.1899 | Soluble |
| 81 | D | B | -1.7133 | Soluble |
| 82 | N | B | -1.7695 | Soluble |
| 83 | S | B | -1.6438 | Soluble |
| 84 | K | B | -2.4531 | Soluble |
| 85 | N | B | -1.9163 | Soluble |
| 86 | T | B | -1.0471 | Soluble |
| 87 | L | B | 0.0000 | Buried |
| 88 | Y | B | -0.2189 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | Q | B | -1.1016 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | N | B | -2.1916 | Soluble |
| 93 | G | B | -1.9508 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -2.6322 | Soluble |
| 96 | A | B | -1.6993 | Soluble |
| 97 | E | B | -2.3040 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.5437 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.5784 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | A | B | 0.0000 | Buried |
| 106 | R | B | 0.0000 | Buried |
| 107 | D | B | 0.0000 | Buried |
| 108 | L | B | -0.4483 | Soluble |
| 109 | R | B | -1.4152 | Soluble |
| 110 | T | B | -0.6424 | Soluble |
| 113 | G | B | 0.0000 | Buried |
| 114 | P | B | 0.0000 | Buried |
| 115 | F | B | 0.0000 | Buried |
| 116 | D | B | 0.0000 | Buried |
| 117 | Y | B | 0.3734 | Aggregation-prone |
| 118 | W | B | -0.1596 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.5582 | Soluble |
| 121 | G | B | -0.4956 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | L | B | 1.2252 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | 0.0589 | Aggregation-prone |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -0.5587 | Soluble |
| 128 | S | B | -0.3808 | Soluble |
| 129 | A | B | -0.2965 | Soluble |
| 130 | S | B | -0.4350 | Soluble |
| 131 | T | B | -0.5440 | Soluble |
| 132 | K | B | -1.1230 | Soluble |
| 133 | G | B | -1.3609 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.3326 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.1609 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -1.1689 | Soluble |
| 141 | P | B | 0.0000 | Buried |
| 142 | S | B | -1.0445 | Soluble |
| 143 | S | B | -1.1510 | Soluble |
| 144 | K | B | -1.1094 | Soluble |
| 145 | S | B | 0.0000 | Buried |
| 146 | T | B | -0.6792 | Soluble |
| 147 | S | B | -0.7843 | Soluble |
| 148 | G | B | -0.8824 | Soluble |
| 149 | G | B | -0.9153 | Soluble |
| 150 | T | B | -0.6435 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | -0.3365 | Soluble |
| 159 | D | B | -0.4199 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | -0.4716 | Soluble |
| 163 | E | B | -0.6433 | Soluble |
| 164 | P | B | -0.8954 | Soluble |
| 165 | V | B | -0.7415 | Soluble |
| 166 | T | B | -0.5663 | Soluble |
| 167 | V | B | -0.1583 | Soluble |
| 168 | S | B | -0.3122 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.7560 | Soluble |
| 171 | S | B | -0.5932 | Soluble |
| 172 | G | B | -0.4265 | Soluble |
| 173 | A | B | -0.1944 | Soluble |
| 174 | L | B | 0.0479 | Aggregation-prone |
| 175 | T | B | -0.1432 | Soluble |
| 176 | S | B | -0.1688 | Soluble |
| 177 | G | B | -0.1831 | Soluble |
| 178 | V | B | 0.1562 | Aggregation-prone |
| 179 | H | B | -0.2498 | Soluble |
| 180 | T | B | 0.0492 | Aggregation-prone |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.3240 | Soluble |
| 183 | A | B | 0.1977 | Aggregation-prone |
| 184 | V | B | 0.5579 | Aggregation-prone |
| 185 | L | B | 1.4142 | Aggregation-prone |
| 186 | Q | B | 0.3872 | Aggregation-prone |
| 187 | S | B | 0.0090 | Aggregation-prone |
| 188 | S | B | -0.1422 | Soluble |
| 189 | G | B | 0.0964 | Aggregation-prone |
| 190 | L | B | 0.1476 | Aggregation-prone |
| 191 | Y | B | 0.4323 | Aggregation-prone |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1139 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.5578 | Soluble |
| 201 | S | B | -0.5757 | Soluble |
| 202 | S | B | -0.5940 | Soluble |
| 203 | S | B | -0.6162 | Soluble |
| 204 | L | B | -0.7546 | Soluble |
| 205 | G | B | -0.9537 | Soluble |
| 206 | T | B | -0.7754 | Soluble |
| 207 | Q | B | -1.3320 | Soluble |
| 208 | T | B | -1.2740 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -1.3452 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.4412 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -1.8578 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.7541 | Soluble |
| 217 | P | B | -1.6526 | Soluble |
| 218 | S | B | -1.8382 | Soluble |
| 219 | N | B | -2.5873 | Soluble |
| 220 | T | B | -2.0700 | Soluble |
| 221 | K | B | -2.6712 | Soluble |
| 222 | V | B | -1.6252 | Soluble |
| 223 | D | B | -2.5810 | Soluble |
| 224 | K | B | -2.3304 | Soluble |
| 225 | R | B | -2.7637 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.7540 | Soluble |
| 228 | P | B | -1.7944 | Soluble |
| 229 | K | B | -1.9384 | Soluble |
| 230 | S | B | -1.6781 | Soluble |
| 231 | C | B | -1.9406 | Soluble |
| 232 | D | B | -3.0392 | Soluble |
| 233 | K | B | -2.7173 | Soluble |
| 234 | T | B | -1.4953 | Soluble |
| 1 | E | A | -1.6500 | Soluble |
| 2 | I | A | -0.1643 | Soluble |
| 3 | V | A | 0.8117 | Aggregation-prone |
| 4 | L | A | 0.0000 | Buried |
| 5 | T | A | -0.6961 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -1.1847 | Soluble |
| 8 | P | A | -1.1561 | Soluble |
| 9 | D | A | -2.0496 | Soluble |
| 10 | F | A | -1.1937 | Soluble |
| 11 | Q | A | -0.8918 | Soluble |
| 12 | S | A | -1.0334 | Soluble |
| 13 | V | A | 0.0000 | Buried |
| 14 | T | A | -2.1878 | Soluble |
| 15 | P | A | -2.8220 | Soluble |
| 16 | K | A | -3.5468 | Soluble |
| 17 | E | A | -3.9287 | Soluble |
| 18 | K | A | -3.1399 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | T | A | -0.5309 | Soluble |
| 21 | I | A | 0.0000 | Buried |
| 22 | T | A | -1.0099 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.3065 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.9228 | Soluble |
| 27 | Q | A | -1.6860 | Soluble |
| 28 | S | A | -1.4080 | Soluble |
| 29 | I | A | 0.0000 | Buried |
| 36 | G | A | -0.7932 | Soluble |
| 37 | S | A | -0.4917 | Soluble |
| 38 | S | A | -0.1466 | Soluble |
| 39 | L | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | 0.0000 | Buried |
| 45 | K | A | -1.7584 | Soluble |
| 46 | P | A | -1.9153 | Soluble |
| 47 | D | A | -2.6609 | Soluble |
| 48 | Q | A | -2.6485 | Soluble |
| 49 | S | A | -1.7021 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | K | A | -1.5873 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | K | A | -0.3664 | Soluble |
| 56 | Y | A | 0.0282 | Aggregation-prone |
| 57 | A | A | 0.0000 | Buried |
| 65 | S | A | -0.8521 | Soluble |
| 66 | Q | A | -1.2343 | Soluble |
| 67 | S | A | -0.6887 | Soluble |
| 68 | F | A | -0.4012 | Soluble |
| 69 | S | A | -0.3955 | Soluble |
| 70 | G | A | -0.4468 | Soluble |
| 71 | V | A | -0.3352 | Soluble |
| 72 | P | A | -0.3961 | Soluble |
| 74 | S | A | -0.5971 | Soluble |
| 75 | R | A | -1.1351 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -0.6676 | Soluble |
| 78 | G | A | 0.0000 | Buried |
| 79 | S | A | -0.7391 | Soluble |
| 80 | G | A | -0.8433 | Soluble |
| 83 | S | A | -1.0480 | Soluble |
| 84 | G | A | -1.2630 | Soluble |
| 85 | T | A | -1.8170 | Soluble |
| 86 | D | A | -2.2112 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.7466 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.6250 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | N | A | -2.3562 | Soluble |
| 93 | S | A | -2.8499 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | E | A | -3.1774 | Soluble |
| 96 | A | A | -1.9920 | Soluble |
| 97 | E | A | -2.3613 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | A | A | -1.1992 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | A | A | -0.6693 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | H | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | S | A | -0.1253 | Soluble |
| 108 | S | A | -0.2927 | Soluble |
| 109 | S | A | -0.3437 | Soluble |
| 114 | L | A | 0.0679 | Aggregation-prone |
| 115 | P | A | -0.4124 | Soluble |
| 116 | F | A | 0.0000 | Buried |
| 117 | T | A | 0.0425 | Aggregation-prone |
| 118 | F | A | 0.2399 | Aggregation-prone |
| 119 | G | A | 0.0000 | Buried |
| 120 | P | A | -0.7707 | Soluble |
| 121 | G | A | -0.9963 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -1.2304 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | D | A | 0.0000 | Buried |
| 126 | I | A | -1.2809 | Soluble |
| 127 | K | A | -1.6158 | Soluble |
| 128 | R | A | -1.0165 | Soluble |
| 129 | T | A | 0.0320 | Aggregation-prone |
| 130 | V | A | 0.6479 | Aggregation-prone |
| 131 | A | A | 0.0661 | Aggregation-prone |
| 132 | A | A | -0.0575 | Soluble |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.2113 | Soluble |
| 135 | V | A | 0.0000 | Buried |
| 136 | F | A | 0.0000 | Buried |
| 137 | I | A | 0.0000 | Buried |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.8184 | Soluble |
| 140 | P | A | -0.8449 | Soluble |
| 141 | S | A | -1.6883 | Soluble |
| 142 | D | A | -2.9518 | Soluble |
| 143 | E | A | -2.8717 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.1969 | Soluble |
| 146 | K | A | -2.8354 | Soluble |
| 147 | S | A | -1.7742 | Soluble |
| 148 | G | A | -1.2368 | Soluble |
| 149 | T | A | -1.2326 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -0.8704 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | 0.0000 | Buried |
| 161 | P | A | -1.4113 | Soluble |
| 162 | R | A | -2.3373 | Soluble |
| 163 | E | A | -2.8611 | Soluble |
| 164 | A | A | -1.9241 | Soluble |
| 165 | K | A | -2.0903 | Soluble |
| 166 | V | A | -1.1002 | Soluble |
| 167 | Q | A | -0.8265 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.4338 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -1.5566 | Soluble |
| 172 | N | A | -1.3429 | Soluble |
| 173 | A | A | -0.1035 | Soluble |
| 174 | L | A | 0.7072 | Aggregation-prone |
| 175 | Q | A | -0.1564 | Soluble |
| 176 | S | A | -0.5333 | Soluble |
| 177 | G | A | -0.9224 | Soluble |
| 178 | N | A | -0.8481 | Soluble |
| 179 | S | A | -1.2370 | Soluble |
| 180 | Q | A | -1.5093 | Soluble |
| 181 | E | A | -1.9281 | Soluble |
| 182 | S | A | -0.6808 | Soluble |
| 183 | V | A | -0.3514 | Soluble |
| 184 | T | A | -0.9208 | Soluble |
| 185 | E | A | -2.0993 | Soluble |
| 186 | Q | A | -1.8378 | Soluble |
| 187 | D | A | -1.9803 | Soluble |
| 188 | S | A | -1.9548 | Soluble |
| 189 | K | A | -2.4038 | Soluble |
| 190 | D | A | -2.0621 | Soluble |
| 191 | S | A | -1.9892 | Soluble |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.7575 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.4562 | Soluble |
| 201 | L | A | -0.7204 | Soluble |
| 202 | S | A | -1.1131 | Soluble |
| 203 | K | A | -2.0876 | Soluble |
| 204 | A | A | -1.9731 | Soluble |
| 205 | D | A | -2.7755 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.6789 | Soluble |
| 208 | K | A | -3.6336 | Soluble |
| 209 | H | A | -3.0566 | Soluble |
| 210 | K | A | -2.9525 | Soluble |
| 211 | V | A | -1.4340 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.8007 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.1395 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.5514 | Soluble |
| 220 | G | A | -0.3354 | Soluble |
| 221 | L | A | -0.2468 | Soluble |
| 222 | S | A | -0.5047 | Soluble |
| 223 | S | A | -0.4392 | Soluble |
| 224 | P | A | -0.5374 | Soluble |
| 225 | V | A | -0.0179 | Soluble |
| 226 | T | A | -0.5067 | Soluble |
| 227 | K | A | -0.8271 | Soluble |
| 228 | S | A | -0.7703 | Soluble |
| 229 | F | A | 0.0000 | Buried |
| 230 | N | A | -1.8667 | Soluble |
| 231 | R | A | -2.4800 | Soluble |
| 232 | G | A | -2.1747 | Soluble |
| 233 | E | A | -2.3847 | Soluble |
| 234 | C | A | 0.0000 | Buried |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7708 | 1.7891 | CSV PDB |
| 4.5 | -0.8241 | 1.7891 | CSV PDB |
| 5.0 | -0.8877 | 1.7891 | CSV PDB |
| 5.5 | -0.9506 | 1.7891 | CSV PDB |
| 6.0 | -1.0004 | 1.7891 | CSV PDB |
| 6.5 | -1.0262 | 1.7891 | CSV PDB |
| 7.0 | -1.0259 | 1.7891 | CSV PDB |
| 7.5 | -1.0071 | 1.7891 | CSV PDB |
| 8.0 | -0.9773 | 1.7891 | CSV PDB |
| 8.5 | -0.939 | 1.7891 | CSV PDB |
| 9.0 | -0.8918 | 1.7891 | CSV PDB |