Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYPFTSYGISWVRQAPGQGLEWMGWISTYNGNTNYAQKFQGRVTMTTDTSTTTGYMELRRLRSDDTAVYYCARDYTRGAWFGESLIGGFDNWGQGTLVTVSSASTKGPSVFPLAPSSKSTSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSEIVLTQSPGTLSLSPGERATLSCRASQTVSSTSLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQHDTSLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.4332 | Soluble |
| 2 | V | A | -1.0380 | Soluble |
| 3 | Q | A | -1.5123 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.2835 | Aggregation-prone |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.4375 | Soluble |
| 8 | G | A | -0.3896 | Soluble |
| 9 | A | A | 0.0210 | Aggregation-prone |
| 11 | E | A | -0.1407 | Soluble |
| 12 | V | A | 0.4660 | Aggregation-prone |
| 13 | K | A | -1.0895 | Soluble |
| 14 | K | A | -2.3412 | Soluble |
| 15 | P | A | -2.3978 | Soluble |
| 16 | G | A | -2.1405 | Soluble |
| 17 | A | A | -1.6257 | Soluble |
| 18 | S | A | -1.8416 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -1.6683 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.3239 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -0.5549 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.7372 | Soluble |
| 27 | G | A | -0.8366 | Soluble |
| 28 | Y | A | -0.4289 | Soluble |
| 29 | P | A | -0.2266 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | 0.2481 | Aggregation-prone |
| 36 | S | A | 0.4252 | Aggregation-prone |
| 37 | Y | A | 0.4785 | Aggregation-prone |
| 38 | G | A | 0.0000 | Buried |
| 39 | I | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.5863 | Soluble |
| 45 | A | A | -0.9214 | Soluble |
| 46 | P | A | -0.8610 | Soluble |
| 47 | G | A | -1.2192 | Soluble |
| 48 | Q | A | -1.7378 | Soluble |
| 49 | G | A | -1.0758 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.6393 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | W | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | 0.0000 | Buried |
| 58 | T | A | 0.0000 | Buried |
| 59 | Y | A | 0.5977 | Aggregation-prone |
| 62 | N | A | -0.8762 | Soluble |
| 63 | G | A | -1.4291 | Soluble |
| 64 | N | A | -1.5532 | Soluble |
| 65 | T | A | -1.1882 | Soluble |
| 66 | N | A | -1.2338 | Soluble |
| 67 | Y | A | -1.0887 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | Q | A | -2.7627 | Soluble |
| 70 | K | A | -2.7069 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | Q | A | -2.4756 | Soluble |
| 74 | G | A | -1.6615 | Soluble |
| 75 | R | A | -1.8612 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.6062 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.3840 | Soluble |
| 80 | T | A | -0.5344 | Soluble |
| 81 | D | A | -0.9954 | Soluble |
| 82 | T | A | -0.4537 | Soluble |
| 83 | S | A | -0.5285 | Soluble |
| 84 | T | A | -0.5539 | Soluble |
| 85 | T | A | -0.6033 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | G | A | 0.0000 | Buried |
| 88 | Y | A | -0.2651 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.0504 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | R | A | -2.1999 | Soluble |
| 93 | R | A | -2.9200 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -3.4918 | Soluble |
| 96 | S | A | -2.3285 | Soluble |
| 97 | D | A | -2.5192 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.7733 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2870 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.3995 | Soluble |
| 107 | D | A | 0.0000 | Buried |
| 108 | Y | A | 0.9053 | Aggregation-prone |
| 109 | T | A | 0.0000 | Buried |
| 110 | R | A | -0.2517 | Soluble |
| 111 | G | A | 0.0000 | Buried |
| 111A | A | A | 0.0000 | Buried |
| 111B | W | A | 1.5516 | Aggregation-prone |
| 111C | F | A | 1.6063 | Aggregation-prone |
| 112D | G | A | -0.3039 | Soluble |
| 112C | E | A | -1.3301 | Soluble |
| 112B | S | A | -0.6310 | Soluble |
| 112A | L | A | 0.5621 | Aggregation-prone |
| 112 | I | A | 2.1815 | Aggregation-prone |
| 113 | G | A | 0.0000 | Buried |
| 114 | G | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.8144 | Soluble |
| 117 | N | A | -1.4564 | Soluble |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.2758 | Soluble |
| 121 | G | A | -0.4970 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | L | A | 0.4370 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.1954 | Soluble |
| 128 | S | A | -1.0081 | Soluble |
| 129 | A | A | -0.5502 | Soluble |
| 130 | S | A | -0.5993 | Soluble |
| 131 | T | A | -0.4788 | Soluble |
| 132 | K | A | -1.1464 | Soluble |
| 133 | G | A | -1.3987 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.2769 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | -0.4494 | Soluble |
| 138 | P | A | -1.0151 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.2718 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -1.1206 | Soluble |
| 143 | S | A | -1.7551 | Soluble |
| 144 | K | A | -1.8935 | Soluble |
| 145 | S | A | -1.1572 | Soluble |
| 146 | T | A | -0.7185 | Soluble |
| 147 | S | A | -0.3857 | Soluble |
| 148 | T | A | -0.3120 | Soluble |
| 149 | A | A | 0.0000 | Buried |
| 150 | A | A | 0.0000 | Buried |
| 151 | L | A | 0.0000 | Buried |
| 152 | G | A | 0.0000 | Buried |
| 153 | C | A | 0.0000 | Buried |
| 154 | L | A | 0.0000 | Buried |
| 155 | V | A | 0.0000 | Buried |
| 156 | K | A | 0.0000 | Buried |
| 157 | D | A | -0.4408 | Soluble |
| 158 | Y | A | 0.0000 | Buried |
| 159 | F | A | 0.0000 | Buried |
| 160 | P | A | 0.0000 | Buried |
| 161 | E | A | -0.3458 | Soluble |
| 162 | P | A | -0.8209 | Soluble |
| 163 | V | A | -0.7182 | Soluble |
| 164 | T | A | -0.6593 | Soluble |
| 165 | V | A | -0.1716 | Soluble |
| 166 | S | A | -0.3507 | Soluble |
| 167 | W | A | 0.0000 | Buried |
| 168 | N | A | -0.6754 | Soluble |
| 169 | S | A | -0.5866 | Soluble |
| 170 | G | A | -0.3795 | Soluble |
| 171 | A | A | -0.1448 | Soluble |
| 172 | L | A | 0.0631 | Aggregation-prone |
| 173 | T | A | -0.1450 | Soluble |
| 174 | S | A | -0.2360 | Soluble |
| 175 | G | A | -0.3296 | Soluble |
| 176 | V | A | 0.1255 | Aggregation-prone |
| 177 | H | A | -0.3281 | Soluble |
| 178 | T | A | -0.1956 | Soluble |
| 179 | F | A | 0.0000 | Buried |
| 180 | P | A | -0.3355 | Soluble |
| 181 | A | A | 0.3862 | Aggregation-prone |
| 182 | V | A | 0.5760 | Aggregation-prone |
| 183 | L | A | 1.2246 | Aggregation-prone |
| 184 | Q | A | 0.3421 | Aggregation-prone |
| 185 | S | A | -0.0184 | Soluble |
| 186 | S | A | -0.1771 | Soluble |
| 187 | G | A | 0.0450 | Aggregation-prone |
| 188 | L | A | 0.0916 | Aggregation-prone |
| 189 | Y | A | 0.3864 | Aggregation-prone |
| 190 | S | A | 0.0000 | Buried |
| 191 | L | A | 0.0000 | Buried |
| 192 | S | A | 0.0000 | Buried |
| 193 | S | A | 0.0000 | Buried |
| 194 | V | A | 0.0000 | Buried |
| 195 | V | A | 0.0000 | Buried |
| 196 | T | A | -0.1459 | Soluble |
| 197 | V | A | 0.0000 | Buried |
| 198 | P | A | -0.4995 | Soluble |
| 199 | S | A | -0.4092 | Soluble |
| 200 | S | A | -0.6049 | Soluble |
| 201 | S | A | -0.6813 | Soluble |
| 202 | L | A | -0.8223 | Soluble |
| 203 | G | A | -1.0098 | Soluble |
| 204 | T | A | -0.8603 | Soluble |
| 205 | Q | A | -1.3142 | Soluble |
| 206 | T | A | -1.1125 | Soluble |
| 207 | Y | A | 0.0000 | Buried |
| 208 | I | A | -1.1154 | Soluble |
| 209 | C | A | 0.0000 | Buried |
| 210 | N | A | -1.4939 | Soluble |
| 211 | V | A | 0.0000 | Buried |
| 212 | N | A | -2.1387 | Soluble |
| 213 | H | A | 0.0000 | Buried |
| 214 | K | A | -2.7837 | Soluble |
| 215 | P | A | -1.6181 | Soluble |
| 216 | S | A | -1.8486 | Soluble |
| 217 | N | A | -2.5883 | Soluble |
| 218 | T | A | -2.1446 | Soluble |
| 219 | K | A | -2.8400 | Soluble |
| 220 | V | A | -1.8164 | Soluble |
| 221 | D | A | -2.5207 | Soluble |
| 222 | K | A | -1.9792 | Soluble |
| 223 | K | A | -2.0553 | Soluble |
| 224 | V | A | 0.0000 | Buried |
| 225 | E | A | -2.6827 | Soluble |
| 226 | P | A | -2.1300 | Soluble |
| 227 | K | A | -2.6387 | Soluble |
| 228 | S | A | -1.5559 | Soluble |
| 1 | E | B | -1.7952 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.8193 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.5313 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.8280 | Soluble |
| 8 | P | B | -0.6167 | Soluble |
| 9 | G | B | -0.8993 | Soluble |
| 10 | T | B | -0.6201 | Soluble |
| 11 | L | B | -0.3979 | Soluble |
| 12 | S | B | -0.7035 | Soluble |
| 13 | L | B | -1.0924 | Soluble |
| 14 | S | B | -1.7538 | Soluble |
| 15 | P | B | -2.1129 | Soluble |
| 16 | G | B | -2.4326 | Soluble |
| 17 | E | B | -2.9336 | Soluble |
| 18 | R | B | -3.2782 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.6458 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.9439 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.0735 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.8703 | Soluble |
| 27 | Q | B | -1.4908 | Soluble |
| 28 | T | B | -1.2657 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | S | B | -0.6680 | Soluble |
| 36 | S | B | -0.4238 | Soluble |
| 37 | T | B | 0.3519 | Aggregation-prone |
| 38 | S | B | 0.0000 | Buried |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.5649 | Soluble |
| 46 | P | B | -1.2930 | Soluble |
| 47 | G | B | -1.3448 | Soluble |
| 48 | Q | B | -1.9703 | Soluble |
| 49 | A | B | -1.5811 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -2.2155 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.4763 | Aggregation-prone |
| 56 | G | B | 0.5065 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.5647 | Soluble |
| 66 | S | B | -0.3200 | Soluble |
| 67 | R | B | -1.2484 | Soluble |
| 68 | A | B | -0.7595 | Soluble |
| 69 | T | B | -0.4994 | Soluble |
| 70 | G | B | -0.7669 | Soluble |
| 71 | I | B | -0.9467 | Soluble |
| 72 | P | B | -1.2135 | Soluble |
| 74 | D | B | -2.1480 | Soluble |
| 75 | R | B | -1.9842 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.8894 | Soluble |
| 78 | G | B | -0.4697 | Soluble |
| 79 | S | B | -0.7711 | Soluble |
| 80 | G | B | -1.2216 | Soluble |
| 83 | S | B | -1.1531 | Soluble |
| 84 | G | B | -1.1946 | Soluble |
| 85 | T | B | -1.8350 | Soluble |
| 86 | D | B | -2.6783 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.8686 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.8224 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.4955 | Soluble |
| 93 | R | B | -3.4660 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -2.6549 | Soluble |
| 96 | P | B | -1.7473 | Soluble |
| 97 | E | B | -1.9953 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.5430 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | D | B | -1.3934 | Soluble |
| 114 | T | B | -1.0433 | Soluble |
| 115 | S | B | -0.9717 | Soluble |
| 116 | L | B | 0.0000 | Buried |
| 117 | T | B | -0.0892 | Soluble |
| 118 | F | B | 0.2846 | Aggregation-prone |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.6145 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.1265 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | 0.0000 | Buried |
| 126 | I | B | -0.8904 | Soluble |
| 127 | K | B | -1.5794 | Soluble |
| 128 | R | B | -0.9895 | Soluble |
| 129 | T | B | 0.1184 | Aggregation-prone |
| 130 | V | B | 0.9163 | Aggregation-prone |
| 131 | A | B | 0.2156 | Aggregation-prone |
| 132 | A | B | 0.0070 | Aggregation-prone |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1550 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | -0.0210 | Soluble |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.9565 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.4894 | Soluble |
| 142 | D | B | -2.7145 | Soluble |
| 143 | E | B | -2.0689 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -1.9693 | Soluble |
| 146 | K | B | -2.5751 | Soluble |
| 147 | S | B | -1.6115 | Soluble |
| 148 | G | B | -1.2439 | Soluble |
| 149 | T | B | -0.9958 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.8930 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.6556 | Soluble |
| 162 | R | B | -2.9079 | Soluble |
| 163 | E | B | -3.1985 | Soluble |
| 164 | A | B | -2.2316 | Soluble |
| 165 | K | B | -1.9677 | Soluble |
| 166 | V | B | -1.2561 | Soluble |
| 167 | Q | B | -0.6911 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.5457 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.6623 | Soluble |
| 172 | N | B | -1.2218 | Soluble |
| 173 | A | B | -0.1974 | Soluble |
| 174 | L | B | 0.7531 | Aggregation-prone |
| 175 | Q | B | -0.1489 | Soluble |
| 176 | S | B | -0.4554 | Soluble |
| 177 | G | B | -0.8745 | Soluble |
| 178 | N | B | -0.7635 | Soluble |
| 179 | S | B | -1.0843 | Soluble |
| 180 | Q | B | -1.3403 | Soluble |
| 181 | E | B | -1.7559 | Soluble |
| 182 | S | B | -0.9538 | Soluble |
| 183 | V | B | -0.8928 | Soluble |
| 184 | T | B | -1.2122 | Soluble |
| 185 | E | B | -2.2604 | Soluble |
| 186 | Q | B | -1.8165 | Soluble |
| 187 | D | B | -1.8403 | Soluble |
| 188 | S | B | -1.6875 | Soluble |
| 189 | K | B | -2.1676 | Soluble |
| 190 | D | B | -1.5713 | Soluble |
| 191 | S | B | -1.6523 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.6421 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.4362 | Soluble |
| 201 | L | B | -0.6718 | Soluble |
| 202 | S | B | -1.2327 | Soluble |
| 203 | K | B | -2.0489 | Soluble |
| 204 | A | B | -1.7868 | Soluble |
| 205 | D | B | -2.4746 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.2168 | Soluble |
| 208 | K | B | -3.4873 | Soluble |
| 209 | H | B | -3.0466 | Soluble |
| 210 | K | B | -3.0450 | Soluble |
| 211 | V | B | -1.3112 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.9721 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.1719 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.6173 | Soluble |
| 220 | G | B | -0.2235 | Soluble |
| 221 | L | B | -0.2034 | Soluble |
| 222 | S | B | -0.4501 | Soluble |
| 223 | S | B | -0.4332 | Soluble |
| 224 | P | B | -0.5181 | Soluble |
| 225 | V | B | -0.1010 | Soluble |
| 226 | T | B | -0.6009 | Soluble |
| 227 | K | B | -0.8389 | Soluble |
| 228 | S | B | -0.6810 | Soluble |
| 229 | F | B | -1.2771 | Soluble |
| 230 | N | B | -2.0370 | Soluble |
| 231 | R | B | -2.6146 | Soluble |
| 232 | G | B | -2.3807 | Soluble |
| 233 | E | B | -2.6314 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7229 | 5.2682 | CSV PDB |
| 4.5 | -0.7626 | 5.1911 | CSV PDB |
| 5.0 | -0.8095 | 5.0798 | CSV PDB |
| 5.5 | -0.8543 | 5.0124 | CSV PDB |
| 6.0 | -0.8861 | 4.9457 | CSV PDB |
| 6.5 | -0.8962 | 4.8905 | CSV PDB |
| 7.0 | -0.8841 | 4.8552 | CSV PDB |
| 7.5 | -0.8565 | 4.8387 | CSV PDB |
| 8.0 | -0.8199 | 4.8324 | CSV PDB |
| 8.5 | -0.7765 | 4.8302 | CSV PDB |
| 9.0 | -0.7267 | 4.829 | CSV PDB |