Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYPFTSYGISWVRQAPGQGLEWMGWISTYNGNTNYAQKFQGRVTMTTDTSTTTGYMELRRLRSDDTAVYYCARDYTRGAWFGESLIGGFDNWGQGTLVTVSSASTKGPSVFPLAPSSKSTTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKEIVLTQSPGTLSLSPGERATLSCRASQTVSSTSLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQHDTSLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.3104 | Soluble |
| 2 | V | A | -0.7626 | Soluble |
| 3 | Q | A | -1.1474 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.7308 | Aggregation-prone |
| 6 | Q | A | -0.0763 | Soluble |
| 7 | S | A | -0.4996 | Soluble |
| 8 | G | A | -0.4882 | Soluble |
| 9 | A | A | 0.0593 | Aggregation-prone |
| 11 | E | A | -0.2533 | Soluble |
| 12 | V | A | 0.7747 | Aggregation-prone |
| 13 | K | A | -0.8540 | Soluble |
| 14 | K | A | -2.4413 | Soluble |
| 15 | P | A | -2.7184 | Soluble |
| 16 | G | A | -2.5630 | Soluble |
| 17 | A | A | -2.1233 | Soluble |
| 18 | S | A | -2.2139 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -2.0841 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.4627 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -0.7586 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.6281 | Soluble |
| 27 | G | A | -0.8536 | Soluble |
| 28 | Y | A | -0.3807 | Soluble |
| 29 | P | A | -0.2347 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | 0.1839 | Aggregation-prone |
| 36 | S | A | 0.2545 | Aggregation-prone |
| 37 | Y | A | 0.4639 | Aggregation-prone |
| 38 | G | A | 0.0000 | Buried |
| 39 | I | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.6800 | Soluble |
| 45 | A | A | -1.0291 | Soluble |
| 46 | P | A | -0.7904 | Soluble |
| 47 | G | A | -1.2256 | Soluble |
| 48 | Q | A | -1.8180 | Soluble |
| 49 | G | A | -1.2717 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.2502 | Soluble |
| 52 | W | A | -0.6791 | Soluble |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | W | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | 0.0000 | Buried |
| 58 | T | A | 0.0000 | Buried |
| 59 | Y | A | 0.4511 | Aggregation-prone |
| 62 | N | A | -0.9003 | Soluble |
| 63 | G | A | -1.3345 | Soluble |
| 64 | N | A | -1.5211 | Soluble |
| 65 | T | A | -1.0873 | Soluble |
| 66 | N | A | -0.9786 | Soluble |
| 67 | Y | A | -0.9289 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | Q | A | -2.5330 | Soluble |
| 70 | K | A | -2.6954 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | Q | A | -2.4303 | Soluble |
| 74 | G | A | -1.8023 | Soluble |
| 75 | R | A | -1.9971 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.7784 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.3546 | Soluble |
| 80 | T | A | -0.5400 | Soluble |
| 81 | D | A | -0.8941 | Soluble |
| 82 | T | A | -0.4163 | Soluble |
| 83 | S | A | -0.4930 | Soluble |
| 84 | T | A | -0.5975 | Soluble |
| 85 | T | A | -0.6818 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | G | A | 0.0000 | Buried |
| 88 | Y | A | -0.4034 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.4692 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | R | A | -3.5452 | Soluble |
| 93 | R | A | -3.6862 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -3.6654 | Soluble |
| 96 | S | A | -2.5736 | Soluble |
| 97 | D | A | -2.4702 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.9164 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.3347 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.2671 | Soluble |
| 107 | D | A | 0.0000 | Buried |
| 108 | Y | A | 0.7802 | Aggregation-prone |
| 109 | T | A | 0.0000 | Buried |
| 110 | R | A | -0.4616 | Soluble |
| 111 | G | A | 0.0000 | Buried |
| 111A | A | A | 0.0000 | Buried |
| 111B | W | A | 1.4288 | Aggregation-prone |
| 111C | F | A | 1.5274 | Aggregation-prone |
| 112D | G | A | -0.4815 | Soluble |
| 112C | E | A | -1.4560 | Soluble |
| 112B | S | A | -0.7516 | Soluble |
| 112A | L | A | 0.4351 | Aggregation-prone |
| 112 | I | A | 1.7123 | Aggregation-prone |
| 113 | G | A | 0.0000 | Buried |
| 114 | G | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.7804 | Soluble |
| 117 | N | A | -0.8428 | Soluble |
| 118 | W | A | -0.6528 | Soluble |
| 119 | G | A | -0.8297 | Soluble |
| 120 | Q | A | -1.1327 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | L | A | 0.4883 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.3029 | Soluble |
| 128 | S | A | -1.1767 | Soluble |
| 129 | A | A | -0.7333 | Soluble |
| 130 | S | A | -0.5482 | Soluble |
| 131 | T | A | -0.5562 | Soluble |
| 132 | K | A | -1.2374 | Soluble |
| 133 | G | A | -1.1877 | Soluble |
| 134 | P | A | -0.5162 | Soluble |
| 135 | S | A | -0.2269 | Soluble |
| 136 | V | A | -0.4269 | Soluble |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.2194 | Soluble |
| 139 | L | A | -0.5498 | Soluble |
| 140 | A | A | -0.9302 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -1.0359 | Soluble |
| 143 | S | A | -1.5062 | Soluble |
| 144 | K | A | -1.9868 | Soluble |
| 145 | S | A | -1.3361 | Soluble |
| 146 | T | A | -0.8738 | Soluble |
| 147 | T | A | -0.3186 | Soluble |
| 148 | A | A | 0.0000 | Buried |
| 149 | A | A | 0.0000 | Buried |
| 150 | L | A | 0.0000 | Buried |
| 151 | G | A | 0.0000 | Buried |
| 152 | C | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | V | A | 0.0000 | Buried |
| 155 | K | A | 0.0000 | Buried |
| 156 | D | A | -0.5691 | Soluble |
| 157 | Y | A | 0.0000 | Buried |
| 158 | F | A | 0.0000 | Buried |
| 159 | P | A | -0.3894 | Soluble |
| 160 | E | A | -0.2441 | Soluble |
| 161 | P | A | -0.5809 | Soluble |
| 162 | V | A | -0.6862 | Soluble |
| 163 | T | A | -0.5903 | Soluble |
| 164 | V | A | -0.2812 | Soluble |
| 165 | S | A | -0.4211 | Soluble |
| 166 | W | A | 0.0000 | Buried |
| 167 | N | A | -0.9609 | Soluble |
| 168 | S | A | -0.8128 | Soluble |
| 169 | G | A | -0.6573 | Soluble |
| 170 | A | A | -0.2846 | Soluble |
| 171 | L | A | 0.0291 | Aggregation-prone |
| 172 | T | A | -0.1491 | Soluble |
| 173 | S | A | -0.1747 | Soluble |
| 174 | G | A | -0.0830 | Soluble |
| 175 | V | A | 0.2705 | Aggregation-prone |
| 176 | H | A | -0.4070 | Soluble |
| 177 | T | A | -0.0013 | Soluble |
| 178 | F | A | 0.0000 | Buried |
| 179 | P | A | -0.1298 | Soluble |
| 180 | A | A | 0.4431 | Aggregation-prone |
| 181 | V | A | 0.4464 | Aggregation-prone |
| 182 | L | A | 0.7813 | Aggregation-prone |
| 183 | Q | A | -0.0661 | Soluble |
| 184 | S | A | -0.2956 | Soluble |
| 185 | S | A | -0.3567 | Soluble |
| 186 | G | A | -0.1501 | Soluble |
| 187 | L | A | -0.0462 | Soluble |
| 188 | Y | A | 0.2593 | Aggregation-prone |
| 189 | S | A | 0.2683 | Aggregation-prone |
| 190 | L | A | 0.3361 | Aggregation-prone |
| 191 | S | A | 0.0000 | Buried |
| 192 | S | A | 0.0000 | Buried |
| 193 | V | A | 0.0000 | Buried |
| 194 | V | A | 0.0000 | Buried |
| 195 | T | A | -0.1011 | Soluble |
| 196 | V | A | 0.0000 | Buried |
| 197 | P | A | -0.4341 | Soluble |
| 198 | S | A | -0.6620 | Soluble |
| 199 | S | A | -0.4868 | Soluble |
| 200 | S | A | -0.6930 | Soluble |
| 201 | L | A | 0.0000 | Buried |
| 202 | G | A | -1.4152 | Soluble |
| 203 | T | A | -0.9361 | Soluble |
| 204 | Q | A | -1.5684 | Soluble |
| 205 | T | A | -1.2578 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | I | A | -1.2883 | Soluble |
| 208 | C | A | 0.0000 | Buried |
| 209 | N | A | -1.4594 | Soluble |
| 210 | V | A | 0.0000 | Buried |
| 211 | N | A | -1.8965 | Soluble |
| 212 | H | A | 0.0000 | Buried |
| 213 | K | A | -2.7992 | Soluble |
| 214 | P | A | -1.6703 | Soluble |
| 215 | S | A | -1.8702 | Soluble |
| 216 | N | A | -2.5078 | Soluble |
| 217 | T | A | -2.0889 | Soluble |
| 218 | K | A | -2.5610 | Soluble |
| 219 | V | A | -1.3875 | Soluble |
| 220 | D | A | -2.3746 | Soluble |
| 221 | K | A | -1.8652 | Soluble |
| 222 | K | A | -2.0582 | Soluble |
| 223 | V | A | 0.0000 | Buried |
| 224 | E | A | -2.7899 | Soluble |
| 225 | P | A | -2.1211 | Soluble |
| 226 | K | A | -2.5139 | Soluble |
| 1 | E | B | -1.7370 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.7759 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.3885 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.6448 | Soluble |
| 8 | P | B | -0.6194 | Soluble |
| 9 | G | B | -0.9858 | Soluble |
| 10 | T | B | -0.8994 | Soluble |
| 11 | L | B | -0.6323 | Soluble |
| 12 | S | B | -0.8453 | Soluble |
| 13 | L | B | -1.1721 | Soluble |
| 14 | S | B | -1.8078 | Soluble |
| 15 | P | B | -1.8610 | Soluble |
| 16 | G | B | -2.2890 | Soluble |
| 17 | E | B | -2.8489 | Soluble |
| 18 | R | B | -2.9823 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.6491 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.6518 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -1.7026 | Soluble |
| 25 | A | B | -0.8800 | Soluble |
| 26 | S | B | -0.9410 | Soluble |
| 27 | Q | B | -1.5429 | Soluble |
| 28 | T | B | -1.1947 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | S | B | -0.6755 | Soluble |
| 36 | S | B | -0.3564 | Soluble |
| 37 | T | B | 0.1683 | Aggregation-prone |
| 38 | S | B | 0.0826 | Aggregation-prone |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | -1.0476 | Soluble |
| 45 | K | B | -1.3385 | Soluble |
| 46 | P | B | -1.1924 | Soluble |
| 47 | G | B | -1.2719 | Soluble |
| 48 | Q | B | -1.9857 | Soluble |
| 49 | A | B | -1.3549 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.4503 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.3538 | Aggregation-prone |
| 56 | G | B | 0.2567 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.5625 | Soluble |
| 66 | S | B | -0.3824 | Soluble |
| 67 | R | B | -1.1493 | Soluble |
| 68 | A | B | -0.6549 | Soluble |
| 69 | T | B | -0.4987 | Soluble |
| 70 | G | B | -0.7392 | Soluble |
| 71 | I | B | -0.8299 | Soluble |
| 72 | P | B | -1.1776 | Soluble |
| 74 | D | B | -2.2701 | Soluble |
| 75 | R | B | -1.8863 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.8089 | Soluble |
| 78 | G | B | -0.4719 | Soluble |
| 79 | S | B | -0.6775 | Soluble |
| 80 | G | B | -1.0299 | Soluble |
| 83 | S | B | -0.9553 | Soluble |
| 84 | G | B | -1.0031 | Soluble |
| 85 | T | B | -1.3492 | Soluble |
| 86 | D | B | -1.4851 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.6506 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.7247 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.3125 | Soluble |
| 93 | R | B | -3.1367 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -2.5765 | Soluble |
| 96 | P | B | -1.9091 | Soluble |
| 97 | E | B | -2.3067 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -1.0614 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.7365 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | D | B | -1.2602 | Soluble |
| 114 | T | B | -1.1284 | Soluble |
| 115 | S | B | -0.9143 | Soluble |
| 116 | L | B | 0.0000 | Buried |
| 117 | T | B | -0.2449 | Soluble |
| 118 | F | B | 0.0330 | Aggregation-prone |
| 119 | G | B | -0.2619 | Soluble |
| 120 | G | B | -0.8877 | Soluble |
| 121 | G | B | -0.9757 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.8365 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -1.0567 | Soluble |
| 126 | I | B | -0.8419 | Soluble |
| 127 | K | B | -1.7428 | Soluble |
| 128 | R | B | -1.1728 | Soluble |
| 129 | T | B | 0.0833 | Aggregation-prone |
| 130 | V | B | 1.1701 | Aggregation-prone |
| 131 | A | B | 0.4326 | Aggregation-prone |
| 132 | A | B | -0.0060 | Soluble |
| 133 | P | B | -0.2569 | Soluble |
| 134 | S | B | -0.3058 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.1597 | Aggregation-prone |
| 137 | I | B | 0.1533 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.7031 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.8697 | Soluble |
| 142 | D | B | -3.2736 | Soluble |
| 143 | E | B | -3.1753 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.1728 | Soluble |
| 146 | K | B | -2.8398 | Soluble |
| 147 | S | B | -1.8135 | Soluble |
| 148 | G | B | -1.1727 | Soluble |
| 149 | T | B | -0.9168 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | -0.5711 | Soluble |
| 158 | N | B | -1.2829 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.5159 | Soluble |
| 162 | R | B | -2.8004 | Soluble |
| 163 | E | B | -3.0275 | Soluble |
| 164 | A | B | -2.0092 | Soluble |
| 165 | K | B | -1.6441 | Soluble |
| 166 | V | B | -0.7011 | Soluble |
| 167 | Q | B | -0.3069 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.4638 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.4948 | Soluble |
| 172 | N | B | -1.3937 | Soluble |
| 173 | A | B | -0.3693 | Soluble |
| 174 | L | B | 0.6749 | Aggregation-prone |
| 175 | Q | B | -0.3171 | Soluble |
| 176 | S | B | -0.5843 | Soluble |
| 177 | G | B | -1.0068 | Soluble |
| 178 | N | B | -1.0049 | Soluble |
| 179 | S | B | -1.4283 | Soluble |
| 180 | Q | B | -1.8031 | Soluble |
| 181 | E | B | -2.0916 | Soluble |
| 182 | S | B | -0.8813 | Soluble |
| 183 | V | B | -0.8503 | Soluble |
| 184 | T | B | -1.1473 | Soluble |
| 185 | E | B | -2.3922 | Soluble |
| 186 | Q | B | -2.2257 | Soluble |
| 187 | D | B | -2.4441 | Soluble |
| 188 | S | B | -1.9537 | Soluble |
| 189 | K | B | -2.3705 | Soluble |
| 190 | D | B | -1.9136 | Soluble |
| 191 | S | B | -2.0507 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.8801 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.3681 | Soluble |
| 201 | L | B | -0.3781 | Soluble |
| 202 | S | B | -1.1121 | Soluble |
| 203 | K | B | -1.8861 | Soluble |
| 204 | A | B | -1.7777 | Soluble |
| 205 | D | B | -2.4548 | Soluble |
| 206 | Y | B | -2.2234 | Soluble |
| 207 | E | B | -3.4512 | Soluble |
| 208 | K | B | -3.3954 | Soluble |
| 209 | H | B | -2.5265 | Soluble |
| 210 | K | B | -2.2976 | Soluble |
| 211 | V | B | -0.8349 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | 0.0000 | Buried |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -0.8451 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.5612 | Soluble |
| 220 | G | B | -0.2841 | Soluble |
| 221 | L | B | -0.0353 | Soluble |
| 222 | S | B | -0.4154 | Soluble |
| 223 | S | B | -0.3825 | Soluble |
| 224 | P | B | -0.3307 | Soluble |
| 225 | V | B | 0.1022 | Aggregation-prone |
| 226 | T | B | -0.3848 | Soluble |
| 227 | K | B | -0.6919 | Soluble |
| 228 | S | B | -0.5850 | Soluble |
| 229 | F | B | -0.7524 | Soluble |
| 230 | N | B | -1.6667 | Soluble |
| 231 | R | B | -2.0749 | Soluble |
| 232 | G | B | -1.3748 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6981 | 5.1984 | CSV PDB |
| 4.5 | -0.74 | 5.1058 | CSV PDB |
| 5.0 | -0.7896 | 4.9826 | CSV PDB |
| 5.5 | -0.8365 | 4.8493 | CSV PDB |
| 6.0 | -0.8693 | 4.7754 | CSV PDB |
| 6.5 | -0.8793 | 4.7291 | CSV PDB |
| 7.0 | -0.8663 | 4.7033 | CSV PDB |
| 7.5 | -0.8374 | 4.6925 | CSV PDB |
| 8.0 | -0.7994 | 4.6886 | CSV PDB |
| 8.5 | -0.755 | 4.6872 | CSV PDB |
| 9.0 | -0.7048 | 4.6863 | CSV PDB |